{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Immune+Dysfunction&page=49", "query": { "condition": "Immune Dysfunction", "page": 49 }, "page_size": 10 }, "pagination": { "page": 49, "page_size": 10, "total_count": 20607, "total_pages": 2061, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Immune+Dysfunction&page=50&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Immune+Dysfunction&page=48&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T03:10:36.919Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00022126", "title": "Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Leukemia" ], "interventions": [ { "name": "asparaginase", "type": "DRUG" }, { "name": "cyclophosphamide", "type": "DRUG" }, { "name": "cyclosporine", "type": "DRUG" }, { "name": "cytarabine", "type": "DRUG" }, { "name": "daunorubicin hydrochloride", "type": "DRUG" }, { "name": "dexamethasone", "type": "DRUG" }, { "name": "doxorubicin hydrochloride", "type": "DRUG" }, { "name": "mercaptopurine", "type": "DRUG" }, { "name": "methotrexate", "type": "DRUG" }, { "name": "methylprednisolone", "type": "DRUG" }, { "name": "pegaspargase", "type": "DRUG" }, { "name": "thioguanine", "type": "DRUG" }, { "name": "vincristine sulfate", "type": "DRUG" }, { "name": "allogeneic bone marrow transplantation", "type": "PROCEDURE" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "PROCEDURE", "RADIATION" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "1 Year", "sex": "ALL", "summary": "Up to 1 Year" }, "enrollment_count": 6, "start_date": "2002-11", "completion_date": "2006-04", "has_results": false, "last_update_posted_date": "2014-02-20", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 47, "location_summary": "Phoenix, Arizona • Loma Linda, California • Los Angeles, California + 38 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Loma Linda", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Madera", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00022126" }, { "nct_id": "NCT01253850", "title": "Improving Antiretroviral Medication Adherence Among HIV-infected Youth: Phase I", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "HIV Infection" ], "interventions": [], "intervention_types": [], "sponsor": "Fenway Community Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "24 Years", "sex": "ALL", "summary": "13 Years to 24 Years" }, "enrollment_count": 31, "start_date": "2010-08", "completion_date": "2013-03-06", "has_results": false, "last_update_posted_date": "2017-04-17", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 3, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01253850" }, { "nct_id": "NCT00705250", "title": "Bendamustine HCL in Relapsed and Primary Refractory Hodgkin Lymphoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hodgkin's Disease", "Lymphoma" ], "interventions": [ { "name": "bendamustine hcl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 36, "start_date": "2008-06", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2017-03-03", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00705250" }, { "nct_id": "NCT00024518", "title": "Interferon-Alpha for Diabetes Mellitus Type 1", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Insulin-Dependent Diabetes Mellitus" ], "interventions": [ { "name": "30,000 units hrINF-alpha", "type": "DRUG" }, { "name": "5,000 hrINF-alpha", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "The University of Texas Health Science Center, Houston", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "3 Years to 25 Years" }, "enrollment_count": 57, "start_date": "2001-09", "completion_date": "2008-09", "has_results": false, "last_update_posted_date": "2013-11-19", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 5, "location_summary": "Bethesda, Maryland • Saint Paul, Minnesota • Kansas City, Missouri + 2 more", "locations": [ { "city": "Bethesda", "state": "Maryland" }, { "city": "Saint Paul", "state": "Minnesota" }, { "city": "Kansas City", "state": "Missouri" }, { "city": "Dallas", "state": "Texas" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00024518" }, { "nct_id": "NCT02152826", "title": "Effectiveness of Two Water-Based Potassium Oxalate Desensitizers on Dental Hypersensitivity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dentin Sensitivity" ], "interventions": [ { "name": "Potassium oxalate", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Procter and Gamble", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2014-03", "completion_date": "2014-09", "has_results": true, "last_update_posted_date": "2020-09-18", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02152826" }, { "nct_id": "NCT02495415", "title": "Trial of Intravenous Fenretinide Emulsion for Patients With Relapsed/Refractory Peripheral T-cell Lymphomas", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Peripheral T-cell Lymphoma" ], "interventions": [ { "name": "Fenretinide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "CerRx, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 140, "start_date": "2016-12", "completion_date": "2021-12", "has_results": false, "last_update_posted_date": "2019-07-23", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 11, "location_summary": "Gilbert, Arizona • Los Angeles, California • Atlanta, Georgia + 5 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Westwood", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02495415" }, { "nct_id": "NCT00528489", "title": "Safety and Effectiveness of PENNVAX-B Vaccine Alone, With Il-12, or IL-15 in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "PennVax B", "type": "BIOLOGICAL" }, { "name": "IL-12", "type": "BIOLOGICAL" }, { "name": "IL-15", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 120, "start_date": "2007-10", "completion_date": "2010-01", "has_results": false, "last_update_posted_date": "2021-10-14", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 8, "location_summary": "Birmingham, Alabama • San Francisco, California • Boston, Massachusetts + 4 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "San Francisco", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00528489" }, { "nct_id": "NCT00092274", "title": "Study of HuMax-CD20, a New Drug to Treat Early Stage Non-Hodgkin´s Follicular Lymphoma", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Lymphoma, Follicular" ], "interventions": [ { "name": "HuMax-CD20", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2004-09", "completion_date": "2005-01", "has_results": false, "last_update_posted_date": "2015-04-21", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT00092274" }, { "nct_id": "NCT00582933", "title": "Phase II Trial of a Chemotherapy Alone Regimen of IV Busulfan (Busulfex), Melphalan and Fludarabine as Myeloablative Regimen Followed by an Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplant From an HLA-Identical, or HLA-Non Identical Related or Unrelated Donor", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Leukemia", "Myelodysplastic Syndrome", "Non-Hodgkin's Lymphoma", "Allogeneic Marrow Transplant" ], "interventions": [ { "name": "BUSULFAN, MELPHALAN, FLUDARABINE, G-CSF", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "54 Years", "sex": "ALL", "summary": "Up to 54 Years" }, "enrollment_count": 96, "start_date": "2001-05", "completion_date": "2009-04", "has_results": true, "last_update_posted_date": "2016-02-01", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00582933" }, { "nct_id": "NCT01790152", "title": "Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hodgkin Lymphoma in Remission", "Leukemia in Remission", "Lymphoblastic Lymphoma", "Osteosarcoma", "Recurrent Leukemia", "Recurrent Lymphoma", "Recurrent Malignant Neoplasm" ], "interventions": [ { "name": "Assessment of Therapy Complications", "type": "OTHER" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 420, "start_date": "2014-03-05", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-05-18", "last_synced_at": "2026-10-22T03:10:36.919Z", "location_count": 69, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 57 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01790152" } ] }