{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Immunosenescence",
    "query": {
      "condition": "Immunosenescence"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 14,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Immunosenescence&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T19:21:38.305Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01935271",
      "title": "Nutritional Supplementation and Muscle Health: A Pilot Study on Immune Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Immunosenescence",
        "Sarcopenia"
      ],
      "interventions": [
        {
          "name": "Muscle Armor Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Central Arkansas Veterans Healthcare System",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "60 Years to 80 Years"
      },
      "enrollment_count": 12,
      "start_date": "2013-01",
      "completion_date": "2013-08",
      "has_results": false,
      "last_update_posted_date": "2013-11-13",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01935271"
    },
    {
      "nct_id": "NCT04449926",
      "title": "BCG and Plasma Amyloid in Non-Demented Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer Disease, Late Onset"
      ],
      "interventions": [
        {
          "name": "Bacillus of Calmette and Guerin (BCG)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Mindful Diagnostics and Therapeutics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 49,
      "start_date": "2020-11-09",
      "completion_date": "2021-12-05",
      "has_results": false,
      "last_update_posted_date": "2021-12-23",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "Eau Claire, Wisconsin",
      "locations": [
        {
          "city": "Eau Claire",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04449926"
    },
    {
      "nct_id": "NCT01102374",
      "title": "Vitamin D Supplementation and Acute Respiratory Infection in Older Long-Term Care Residents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Infection"
      ],
      "interventions": [
        {
          "name": "High Dose Vitamin D",
          "type": "DRUG"
        },
        {
          "name": "Standard Dose Vitamin D",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Usual Care",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 107,
      "start_date": "2010-05",
      "completion_date": "2016-07",
      "has_results": true,
      "last_update_posted_date": "2017-04-21",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01102374"
    },
    {
      "nct_id": "NCT04162223",
      "title": "Hepatitis B Vaccine in Seniors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Hepatitis B Vaccination"
      ],
      "interventions": [
        {
          "name": "Subcutaneous fat injection of Recombivax-HB",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Intramuscular injection of Recombivax-HB",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2000-03-29",
      "completion_date": "2003-05-20",
      "has_results": false,
      "last_update_posted_date": "2019-11-14",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04162223"
    },
    {
      "nct_id": "NCT01262300",
      "title": "Vitamin D Supplementation And Varicella Zoster Virus Vaccine Responsiveness In Older Long-Term Care Residents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Immunosenescence",
        "Shingles"
      ],
      "interventions": [
        {
          "name": "Varicella Zoster Virus Vaccine (Zostavax)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2010-11",
      "completion_date": "2014-01-23",
      "has_results": false,
      "last_update_posted_date": "2021-06-25",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01262300"
    },
    {
      "nct_id": "NCT01827462",
      "title": "Comparison of Immune Responses to Influenza Vaccine In Adults of Different Ages (SLVP015 2007-2017)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Influenza"
      ],
      "interventions": [
        {
          "name": "Trivalent, inactivated influenza vaccine (TIV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Quadrivalent, inactivated influenza vaccine (IIV4)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "High-Dose Trivalent, inactivated influenza vaccine (TIV High-Dose)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 136,
      "start_date": "2007-10",
      "completion_date": "2017-03",
      "has_results": true,
      "last_update_posted_date": "2017-07-11",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01827462"
    },
    {
      "nct_id": "NCT05234203",
      "title": "The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Immunity Disorders",
        "Aging",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "HTB Rejuvenate",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Big Bold Health, PBC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 50,
      "start_date": "2022-03-25",
      "completion_date": "2022-10-07",
      "has_results": false,
      "last_update_posted_date": "2022-12-06",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "Bainbridge Island, Washington",
      "locations": [
        {
          "city": "Bainbridge Island",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05234203"
    },
    {
      "nct_id": "NCT07462767",
      "title": "Precision Microbiota Interventions for Senoreduction Trial",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "HIV Infections",
        "Alcohol Drinking",
        "Aging",
        "Immunosenescence"
      ],
      "interventions": [
        {
          "name": "Limosilactobacillus reuteri",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Blueberry extract",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Louisiana State University Health Sciences Center in New Orleans",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2026-04-01",
      "completion_date": "2029-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07462767"
    },
    {
      "nct_id": "NCT04375657",
      "title": "Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Epigenetic Aging",
        "Immunosenescence"
      ],
      "interventions": [
        {
          "name": "TRIIM Treatment",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Active Control",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Intervene Immune, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 85,
      "start_date": "2020-11-23",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-07",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 1,
      "location_summary": "Torrance, California",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04375657"
    },
    {
      "nct_id": "NCT04983017",
      "title": "2021 PMT iAge® Intervention Trial by Edifice Health",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Inflammation",
        "Inflammaging"
      ],
      "interventions": [
        {
          "name": "Dietary supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Edifice Health",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 781,
      "start_date": "2021-08-10",
      "completion_date": "2022-09-09",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-06-26T19:21:38.305Z",
      "location_count": 2,
      "location_summary": "Greenbrae, California • Suwanee, Georgia",
      "locations": [
        {
          "city": "Greenbrae",
          "state": "California"
        },
        {
          "city": "Suwanee",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04983017"
    }
  ]
}