{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Injury%2C+Ankle&page=4",
    "query": {
      "condition": "Injury, Ankle",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 193,
    "total_pages": 20,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Injury%2C+Ankle&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Injury%2C+Ankle&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-05T10:19:52.201Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00765700",
      "title": "Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Sprain",
        "Strain",
        "Acute Soft Tissue Injury"
      ],
      "interventions": [
        {
          "name": "Topical Ketoprofen 10% Cream",
          "type": "DRUG"
        },
        {
          "name": "Topical Placebo Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Imprimis Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 364,
      "start_date": "2008-09",
      "completion_date": "2009-09",
      "has_results": false,
      "last_update_posted_date": "2013-09-27",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00765700"
    },
    {
      "nct_id": "NCT04961957",
      "title": "Waterproof Casting Versus Standard Casting for Short Leg Walking Casts",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures",
        "Foot Fracture",
        "Ankle Sprains",
        "Foot Sprain",
        "Toe-walking",
        "Tendonitis of Foot",
        "Apophysitis; Juvenile"
      ],
      "interventions": [
        {
          "name": "Waterproof padding",
          "type": "DEVICE"
        },
        {
          "name": "Non-waterproof padding",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "West Virginia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "5 Years to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-09",
      "completion_date": "2028-02",
      "has_results": false,
      "last_update_posted_date": "2025-09-08",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Morgantown, West Virginia",
      "locations": [
        {
          "city": "Morgantown",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04961957"
    },
    {
      "nct_id": "NCT01639144",
      "title": "Use of Platelet-Rich Plasma (PRP) and Platelet-Poor Plasma (PPP) to Prevent Infection and Delayed Wound Healing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elective Foot and Ankle Surgery."
      ],
      "interventions": [
        {
          "name": "PRP and PPP",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Gary M. Kiebzak, Ph.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 515,
      "start_date": "2012-07",
      "completion_date": "2015-03",
      "has_results": true,
      "last_update_posted_date": "2015-05-22",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Coral Gables, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01639144"
    },
    {
      "nct_id": "NCT02498717",
      "title": "Preliminary Review of Cold and Active Compression Therapy for Traumatic Calcaneus or Ankle Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures"
      ],
      "interventions": [
        {
          "name": "GameReady",
          "type": "DEVICE"
        },
        {
          "name": "RICE",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "AdventHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 55,
      "start_date": "2015-06-03",
      "completion_date": "2017-07-26",
      "has_results": false,
      "last_update_posted_date": "2018-02-15",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02498717"
    },
    {
      "nct_id": "NCT03809520",
      "title": "An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthopedic Disorder",
        "Trauma",
        "Ankle Fractures",
        "Post-traumatic Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "pedCAT",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "J L Marsh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 97,
      "start_date": "2017-02-01",
      "completion_date": "2022-03-31",
      "has_results": true,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03809520"
    },
    {
      "nct_id": "NCT05456295",
      "title": "Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy",
        "Lower Limb Injury",
        "Post-Traumatic Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Custom Dynamic Orthosis (CDO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 35,
      "start_date": "2023-05-17",
      "completion_date": "2025-09-29",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05456295"
    },
    {
      "nct_id": "NCT04972578",
      "title": "Comparison of Gait in Syndesmosis Injuries Treated With Screw Fixation vs Suture Button",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Disruption of Ankle Syndesmosis"
      ],
      "interventions": [
        {
          "name": "Suture Button vs Screw Fixation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2021-10-01",
      "completion_date": "2026-01-09",
      "has_results": false,
      "last_update_posted_date": "2026-01-13",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 3,
      "location_summary": "Bellevue, Nebraska • Omaha, Nebraska",
      "locations": [
        {
          "city": "Bellevue",
          "state": "Nebraska"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04972578"
    },
    {
      "nct_id": "NCT03507803",
      "title": "Effects of Gait Biofeedback and Impairment-based Rehabilitation in Individuals With Chronic Ankle Instability",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ankle Sprains",
        "Ankle Injuries"
      ],
      "interventions": [
        {
          "name": "Gait Biofeedback",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 60,
      "start_date": "2018-02-15",
      "completion_date": "2020-03",
      "has_results": false,
      "last_update_posted_date": "2018-05-16",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03507803"
    },
    {
      "nct_id": "NCT05062265",
      "title": "Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Syndesmotic Injuries",
        "Ligament Rupture",
        "Bimalleolar Fractures",
        "Trimalleolar Fractures"
      ],
      "interventions": [
        {
          "name": "Tight rope fixation",
          "type": "DEVICE"
        },
        {
          "name": "Tight rope fixation with an anterior inferior tibiofibular ligament (AITFL) repair augmentation with an internal brace",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vann Virginia Center for Orthopaedics dba Atlantic Orthopaedic Specialists",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 23,
      "start_date": "2022-01-31",
      "completion_date": "2023-12-31",
      "has_results": true,
      "last_update_posted_date": "2025-02-19",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Virginia Beach, Virginia",
      "locations": [
        {
          "city": "Virginia Beach",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05062265"
    },
    {
      "nct_id": "NCT07401095",
      "title": "BioBrace® in Arthroscopic Brostrom Lateral Ankle Ligament Repair",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ATFL",
        "Lateral Ankle Instability",
        "Anterior Talofibular Ligament",
        "Anterior Talofibular Ligament Injury",
        "Brostrom Procedure",
        "Brostrom",
        "Ankle"
      ],
      "interventions": [
        {
          "name": "Brostrom repair with augmentation",
          "type": "DEVICE"
        },
        {
          "name": "Brostrom repair without augmentation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Hancock Orthopedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2025-12-08",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-10-05T10:19:52.201Z",
      "location_count": 1,
      "location_summary": "Greenfield, Indiana",
      "locations": [
        {
          "city": "Greenfield",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07401095"
    }
  ]
}