{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Instability%2C+Joint&page=2",
    "query": {
      "condition": "Instability, Joint",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Instability%2C+Joint&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T01:35:26.613Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03418051",
      "title": "Mechanisms of Manual Therapies in CAI Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Inversion Sprain",
        "Chronic Instability of Joint"
      ],
      "interventions": [
        {
          "name": "Joint Mobilization",
          "type": "OTHER"
        },
        {
          "name": "Massage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 60,
      "start_date": "2018-09-01",
      "completion_date": "2020-10-09",
      "has_results": true,
      "last_update_posted_date": "2021-08-27",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03418051"
    },
    {
      "nct_id": "NCT04222244",
      "title": "Musculoskeletal Impairment in Headaches Attributed to Rhinosinusitis",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Headache"
      ],
      "interventions": [
        {
          "name": "No intervention will be administered. We are only performing tests and measures.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Des Moines University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 82,
      "start_date": "2020-03-01",
      "completion_date": "2022-12-01",
      "has_results": false,
      "last_update_posted_date": "2020-09-18",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 7,
      "location_summary": "Hartford, Connecticut • Des Moines, Iowa • Lafayette, New Jersey + 4 more",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Des Moines",
          "state": "Iowa"
        },
        {
          "city": "Lafayette",
          "state": "New Jersey"
        },
        {
          "city": "Totowa",
          "state": "New Jersey"
        },
        {
          "city": "Youngstown",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04222244"
    },
    {
      "nct_id": "NCT00115401",
      "title": "Gait Adaptations to Passive Dynamic Ankle-Foot Orthosis Use",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Joint Instability"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2005-06-16",
      "completion_date": "2007-10-17",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00115401"
    },
    {
      "nct_id": "NCT04554212",
      "title": "Blood Flow Restriction Training After Patellar INStability",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patellar Dislocation",
        "Knee Injuries",
        "Leg Injury",
        "Wounds and Injuries"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction Training",
          "type": "DEVICE"
        },
        {
          "name": "Sham Blood Flow Restriction Training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Caitlin Conley",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "14 Years to 40 Years"
      },
      "enrollment_count": 78,
      "start_date": "2020-09-09",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-03",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 4,
      "location_summary": "Lexington, Kentucky • Foxborough, Massachusetts",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Foxborough",
          "state": "Massachusetts"
        },
        {
          "city": "Foxborough",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04554212"
    },
    {
      "nct_id": "NCT04697004",
      "title": "SMR Stemless Reverse Vs SMR Reverse Shoulder System",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement"
      ],
      "interventions": [
        {
          "name": "Investigational Arm: SMR Stemless Reverse",
          "type": "DEVICE"
        },
        {
          "name": "Control Arm: SMR Reverse Shoulder System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Limacorporate S.p.a",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2021-04-01",
      "completion_date": "2026-03-30",
      "has_results": false,
      "last_update_posted_date": "2024-10-02",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 11,
      "location_summary": "Los Angeles, California • Denver, Colorado • Boca Raton, Florida + 7 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Boca Raton",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04697004"
    },
    {
      "nct_id": "NCT00005923",
      "title": "The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Center for Research Resources (NCRR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "23 Years",
        "sex": "ALL",
        "summary": "15 Years to 23 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005923"
    },
    {
      "nct_id": "NCT00601471",
      "title": "Effects of Proximal and Distal Tibiofibular Joint Manipulation on Lower Extremity Muscle Activation, Ankle Range of Motion, and Functional Outcome Scores in Individuals With Chronic Ankle Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprain",
        "Ankle Injuries",
        "Sprain"
      ],
      "interventions": [
        {
          "name": "proximal tibiofibular manipulation",
          "type": "OTHER"
        },
        {
          "name": "distal tibiofibular manipulation",
          "type": "OTHER"
        },
        {
          "name": "no intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 61,
      "start_date": "2007-04",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2010-06-24",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00601471"
    },
    {
      "nct_id": "NCT01438905",
      "title": "Effect of Joint Mobilization in the Treatment of Chronic Ankle Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprain"
      ],
      "interventions": [
        {
          "name": "Small amplitude (Grade IV) mobilization",
          "type": "OTHER"
        },
        {
          "name": "High velocity, low amplitude (Grade V) mobilization",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "19 Years to 45 Years · Male only"
      },
      "enrollment_count": 30,
      "start_date": "2011-09",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2018-02-23",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01438905"
    },
    {
      "nct_id": "NCT02469662",
      "title": "Clinical Outcomes Study of the Nexel Total Elbow",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elbow Joint Destruction",
        "Post-traumatic Lesions",
        "Ankylosed Joints",
        "Advanced Rheumatoid Arthritis",
        "Joint Instability or Loss of Motion",
        "Acute Comminuted Articular Fracture of Elbow Joint Surfaces",
        "Bone Loss Contributing to Elbow Instability",
        "Bilateral Ankylosis From Causes Other Than Active Sepsis",
        "Post-traumatic Arthritis",
        "Degenerative Arthritis"
      ],
      "interventions": [
        {
          "name": "Nexel Total Elbow",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 134,
      "start_date": "2015-06",
      "completion_date": "2036-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 4,
      "location_summary": "Golden, Colorado • Charlotte, North Carolina • Philadelphia, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Golden",
          "state": "Colorado"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Germantown",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02469662"
    },
    {
      "nct_id": "NCT04770987",
      "title": "Lateral Neck Flexor Endurance and Hyperlaxity",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Physical Endurance",
        "Hypermobility, Joint",
        "Muscular Weakness"
      ],
      "interventions": [
        {
          "name": "lateral neck flexor endurance test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Hartford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2021-02-26",
      "completion_date": "2021-07-16",
      "has_results": false,
      "last_update_posted_date": "2021-07-22",
      "last_synced_at": "2026-07-24T01:35:26.613Z",
      "location_count": 1,
      "location_summary": "West Hartford, Connecticut",
      "locations": [
        {
          "city": "West Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04770987"
    }
  ]
}