{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Insulin+Sensitivity%2FResistance&page=2",
    "query": {
      "condition": "Insulin Sensitivity/Resistance",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Insulin+Sensitivity%2FResistance&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:47:15.598Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02124759",
      "title": "Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Insulin Sensitivity"
      ],
      "interventions": [
        {
          "name": "Sevelamer",
          "type": "DRUG"
        },
        {
          "name": "Synbiotic",
          "type": "DRUG"
        },
        {
          "name": "Maltodextrin",
          "type": "DRUG"
        },
        {
          "name": "High Fat diet",
          "type": "OTHER"
        },
        {
          "name": "Low Fat diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2014-04-02",
      "completion_date": "2020-03-30",
      "has_results": true,
      "last_update_posted_date": "2021-10-15",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02124759"
    },
    {
      "nct_id": "NCT03486223",
      "title": "Soluble Epoxide Hydrolase Inhibition and Insulin Resistance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes Mellitus",
        "Endocrine System Diseases",
        "Glucose Metabolism Disorders",
        "PreDiabetes",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "GSK2256294",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 16,
      "start_date": "2018-05-17",
      "completion_date": "2021-11-18",
      "has_results": true,
      "last_update_posted_date": "2023-03-23",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03486223"
    },
    {
      "nct_id": "NCT00687128",
      "title": "Exercise Dose-Response on Features of the Metabolic Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insulin Resistance",
        "Metabolic Syndrome",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Low-intensity treadmill exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Moderate-intensity treadmill exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Non-aerobic stretching exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Charles Drew University of Medicine and Science",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 93,
      "start_date": "2004-10",
      "completion_date": "2010-04",
      "has_results": false,
      "last_update_posted_date": "2012-02-28",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00687128"
    },
    {
      "nct_id": "NCT00743756",
      "title": "Study of a Home Delivered Meal Program on Obese Elderly African American Subjects With Type 2 Diabetes Mellitus (DM)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "home-delivered meals",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "diabetes education for 12 months",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 38,
      "start_date": "2006-04",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2014-06-10",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00743756"
    },
    {
      "nct_id": "NCT06550115",
      "title": "Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Circadian Rhythm Sleep Disorder of Shift Work Type",
        "Metabolic Disease",
        "Insulin Sensitivity",
        "Blood Pressure"
      ],
      "interventions": [
        {
          "name": "Time-restricted eating",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control eating",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Colorado State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "2024-03-01",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2025-12-17",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "Fort Collins, Colorado",
      "locations": [
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06550115"
    },
    {
      "nct_id": "NCT02740439",
      "title": "Persea Americana for Total Health (PATH ) Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity, Abdominal",
        "Insulin Resistance",
        "Insulin Sensitivity"
      ],
      "interventions": [
        {
          "name": "Avocado",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "25 Years to 45 Years"
      },
      "enrollment_count": 200,
      "start_date": "2016-02",
      "completion_date": "2019-02",
      "has_results": false,
      "last_update_posted_date": "2016-10-17",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02740439"
    },
    {
      "nct_id": "NCT05065372",
      "title": "MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Type 1 Diabetes",
        "Diabetic Kidney Disease",
        "Cardiovascular Diseases",
        "Endothelial Dysfunction",
        "Insulin Sensitivity"
      ],
      "interventions": [
        {
          "name": "Metformin Hcl 1000Mg Tab",
          "type": "DRUG"
        },
        {
          "name": "Aminohippurate Sodium 20 % Injection",
          "type": "DRUG"
        },
        {
          "name": "Iohexol 300 Mg/mL Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kalie Tommerdahl",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "12 Years to 25 Years"
      },
      "enrollment_count": 60,
      "start_date": "2022-07-01",
      "completion_date": "2027-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-13",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • Seattle, Washington",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05065372"
    },
    {
      "nct_id": "NCT00687960",
      "title": "Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperglycemia"
      ],
      "interventions": [
        {
          "name": "Resistant starch type 4 - raw",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Resistant Starch Type 4 - Cooked",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Dextrose",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Puffed Wheat",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Kansas State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 13,
      "start_date": "2006-11",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2008-06-02",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "Manhattan, Kansas",
      "locations": [
        {
          "city": "Manhattan",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00687960"
    },
    {
      "nct_id": "NCT05195164",
      "title": "The Effects of Orchiectomy and Age on Vascular and Metabolic Health in Older Versus Younger Transgender Women",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Transgender",
        "Gender Identity",
        "Vascular Stiffness",
        "Vascular Inflammation",
        "Insulin Sensitivity",
        "Blood Pressure",
        "Lipid Disorder",
        "Appetitive Behavior"
      ],
      "interventions": [
        {
          "name": "No intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 17,
      "start_date": "2021-03-22",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05195164"
    },
    {
      "nct_id": "NCT04484987",
      "title": "The Effect of Time-Restricted Eating in Cardiometabolic Health",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Pre-diabetes"
      ],
      "interventions": [
        {
          "name": "9 hours daily eating window",
          "type": "OTHER"
        },
        {
          "name": "15 hours daily eating window",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 55,
      "start_date": "2020-11-20",
      "completion_date": "2024-05-20",
      "has_results": false,
      "last_update_posted_date": "2024-08-22",
      "last_synced_at": "2026-06-11T01:47:15.598Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04484987"
    }
  ]
}