{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Insulin+Sensitivity%2FResistance&page=4",
    "query": {
      "condition": "Insulin Sensitivity/Resistance",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 320,
    "total_pages": 32,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Insulin+Sensitivity%2FResistance&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Insulin+Sensitivity%2FResistance&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T02:06:36.792Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00865683",
      "title": "DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Overweight and Obesity",
        "Insulin Resistance",
        "Diabetes, Gestational",
        "Hypertension in Pregnancy",
        "Pre-Eclampsia"
      ],
      "interventions": [
        {
          "name": "DHA Supplements",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Supplements",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 90,
      "start_date": "2009-04",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2009-07-15",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00865683"
    },
    {
      "nct_id": "NCT01663207",
      "title": "Characterization of the Variability Of Insulin Secretory Parameters in the Meal Tolerance and the Maximal Stimulation Tests of Subjects With Prediabetes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Foundation for the National Institutes of Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-05",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2014-07-16",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01663207"
    },
    {
      "nct_id": "NCT07131384",
      "title": "Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Males",
        "Females",
        "Sedentary",
        "Metformin",
        "Prediabetes"
      ],
      "interventions": [
        {
          "name": "Dietary Supplement: Inorganic Nitrate (Beetroot juice)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Dietary supplement: Placebo (Nitrate-depleted beetroot juice)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 24,
      "start_date": "2026-01-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07131384"
    },
    {
      "nct_id": "NCT01787617",
      "title": "Aerobic Plus Resistance Training and Insulin Sensitivity in African American Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insulin Resistance",
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Aerobic Plus Resistance Training Group",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Pennington Biomedical Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "70 Years",
        "sex": "MALE",
        "summary": "35 Years to 70 Years · Male only"
      },
      "enrollment_count": 113,
      "start_date": "2012-12",
      "completion_date": "2018-03-31",
      "has_results": true,
      "last_update_posted_date": "2024-10-31",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01787617"
    },
    {
      "nct_id": "NCT04596592",
      "title": "Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Transgenderism",
        "Gender Dysphoria",
        "Insulin Sensitivity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "13 Years to 16 Years"
      },
      "enrollment_count": 90,
      "start_date": "2021-02-15",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-10",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04596592"
    },
    {
      "nct_id": "NCT05358171",
      "title": "Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insulin Sensitivity",
        "24-hour Glucose Control"
      ],
      "interventions": [
        {
          "name": "HIgh UPF controlled diet",
          "type": "OTHER"
        },
        {
          "name": "No UPF controlled diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2023-03-15",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-14",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Blacksburg, Virginia",
      "locations": [
        {
          "city": "Blacksburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05358171"
    },
    {
      "nct_id": "NCT03407833",
      "title": "Physiologic and Functional Adaptations of Insulin Sensitive Tissues",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetes",
        "Insulin Resistance",
        "Obesity",
        "Bariatric Surgery Candidate",
        "Roux-en-y Gastric Bypass",
        "Liver Diseases"
      ],
      "interventions": [
        {
          "name": "Endoscopy biopsy",
          "type": "OTHER"
        },
        {
          "name": "Surgical biopsy",
          "type": "OTHER"
        },
        {
          "name": "Mixed-meal tolerance test",
          "type": "OTHER"
        },
        {
          "name": "Excised Liver Tissue Sampling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2018-02-13",
      "completion_date": "2028-02",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03407833"
    },
    {
      "nct_id": "NCT06998238",
      "title": "Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight and Obesity",
        "Hyperandrogenemia",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "Mediterranean-based, carbohydrate restricted, calorie reduced diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 45 Years · Female only"
      },
      "enrollment_count": 8,
      "start_date": "2024-01-07",
      "completion_date": "2026-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06998238"
    },
    {
      "nct_id": "NCT01618630",
      "title": "Amino Acid Supplementation in Recovery From Severe Burns",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burn Injury"
      ],
      "interventions": [
        {
          "name": "EAA Supplementation + Exercise Training",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo + Exercise Training",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-05",
      "completion_date": "2017-12-05",
      "has_results": false,
      "last_update_posted_date": "2018-12-11",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01618630"
    },
    {
      "nct_id": "NCT07265323",
      "title": "Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer s Disease",
        "Alzheimer Blood Biomarkers",
        "Insulin Sensitivity"
      ],
      "interventions": [
        {
          "name": "Physiological Insulin Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Pennington Biomedical Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2025-12",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2025-12-04",
      "last_synced_at": "2026-10-06T02:06:36.792Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07265323"
    }
  ]
}