{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Intensive+Care+Unit+Acquired+Weakness&page=2",
    "query": {
      "condition": "Intensive Care Unit Acquired Weakness",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Intensive+Care+Unit+Acquired+Weakness&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:14:08.091Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02523690",
      "title": "Evaluating Muscle Weakness Improvement With Lorcaserin in ICU",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Muscle Weakness",
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Lorcaserin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2015-12",
      "completion_date": "2017-12",
      "has_results": true,
      "last_update_posted_date": "2020-01-13",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02523690"
    },
    {
      "nct_id": "NCT05537298",
      "title": "Muscle Recovery After Critical Illness",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ICU Acquired Weakness",
        "Post Intensive Care Unit Syndrome",
        "Muscle Weakness",
        "Critical Illness"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Kirby Mayer",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 209,
      "start_date": "2022-10-18",
      "completion_date": "2027-08-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 3,
      "location_summary": "Birmingham, Alabama • Lexington, Kentucky • Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05537298"
    },
    {
      "nct_id": "NCT00937001",
      "title": "Critical Illness Myopathy as a Cause of Debilitating ICU-Acquired Weakness",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopathy",
        "Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Biopsy/Ultrasound",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 50,
      "start_date": "2008-11",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-02",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00937001"
    },
    {
      "nct_id": "NCT07362862",
      "title": "MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis",
        "Critical Illness",
        "ICU-acquired Muscle Weakness",
        "ICU-acquired Weakness",
        "ICUAW",
        "Sarcopenia",
        "Secondary Sarcopenia"
      ],
      "interventions": [
        {
          "name": "Electrical Muscle Stimulation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Health Discovery Labs",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 50,
      "start_date": "2026-05-05",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 3,
      "location_summary": "Rochester, Minnesota • Austin, Texas",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07362862"
    },
    {
      "nct_id": "NCT00322010",
      "title": "Early Directed Physical Therapy in the Management of Mechanically Ventilated Patients in a Medical Intensive Care Unit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mechanically Ventilated Patients"
      ],
      "interventions": [
        {
          "name": "early PT OT",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2005-06",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2014-03-18",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00322010"
    },
    {
      "nct_id": "NCT04249141",
      "title": "Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Implementation Science",
        "Delirium",
        "Intensive Care Unit Acquired Weakness",
        "Pain",
        "Sedation Complication",
        "Mechanical Ventilation Complication"
      ],
      "interventions": [
        {
          "name": "Survey and concept mapping",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 0,
      "start_date": "2020-01-28",
      "completion_date": "2023-07-31",
      "has_results": false,
      "last_update_posted_date": "2023-08-16",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04249141"
    },
    {
      "nct_id": "NCT02247895",
      "title": "Treatment of Muscle Weakness in Critically Ill Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Respiratory Failure",
        "Myopathy",
        "Weakness"
      ],
      "interventions": [
        {
          "name": "Sham Treatment",
          "type": "DEVICE"
        },
        {
          "name": "Electrical stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Gerald Supinski",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2016-12",
      "completion_date": "2018-02",
      "has_results": false,
      "last_update_posted_date": "2020-06-22",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02247895"
    },
    {
      "nct_id": "NCT02509520",
      "title": "Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Weakness",
        "Critical Illness",
        "Sarcopenia"
      ],
      "interventions": [
        {
          "name": "MPR and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2015-05-01",
      "completion_date": "2026-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-03",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02509520"
    },
    {
      "nct_id": "NCT03471247",
      "title": "CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intensive Care Unit Acquired Weakness",
        "Critical Care",
        "Mechanical Ventilation",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "In-Bed Cycle Ergometer",
          "type": "DEVICE"
        },
        {
          "name": "Routine PT",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "McMaster University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 360,
      "start_date": "2018-10-15",
      "completion_date": "2024-08",
      "has_results": false,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Durham, North Carolina",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03471247"
    },
    {
      "nct_id": "NCT04160039",
      "title": "Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Liver Cirrhoses",
        "Liver Failure",
        "ICU Acquired Weakness"
      ],
      "interventions": [
        {
          "name": "Cycle ergometry",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 97,
      "start_date": "2019-11-10",
      "completion_date": "2022-09-01",
      "has_results": false,
      "last_update_posted_date": "2024-03-20",
      "last_synced_at": "2026-05-22T08:14:08.091Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04160039"
    }
  ]
}