{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Intestinal+Perforation&page=2",
    "query": {
      "condition": "Intestinal Perforation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Intestinal+Perforation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:54:53.161Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02784821",
      "title": "Antibiotic \"Dysbiosis\" in Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Enterocolitis, Necrotizing",
        "Bacteremia",
        "Bronchopulmonary Dysplasia",
        "Intraventricular Hemorrhage",
        "Periventricular Leukomalacia",
        "Chronic Lung Disease",
        "Ileal Perforation"
      ],
      "interventions": [
        {
          "name": "Antibiotic",
          "type": "DRUG"
        },
        {
          "name": "Gastric fluid",
          "type": "OTHER"
        },
        {
          "name": "Breast milk",
          "type": "OTHER"
        },
        {
          "name": "Stool samples",
          "type": "OTHER"
        },
        {
          "name": "Antibiotics",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "33 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 33 Weeks"
      },
      "enrollment_count": 98,
      "start_date": "2017-01-16",
      "completion_date": "2019-09-11",
      "has_results": true,
      "last_update_posted_date": "2024-06-05",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02784821"
    },
    {
      "nct_id": "NCT00879294",
      "title": "The Effect of Gum Chewing on Postoperative Ileus",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perforated Appendicitis"
      ],
      "interventions": [
        {
          "name": "Motion sickness wristband",
          "type": "DEVICE"
        },
        {
          "name": "Chewing Gum",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-11-06",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00879294"
    },
    {
      "nct_id": "NCT00195923",
      "title": "Prospective Randomized Evaluation of Antibiotic Regimen Following Appendectomy for Perforated Appendicitis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Perforated Appendicitis"
      ],
      "interventions": [
        {
          "name": "Ampicillin, gentamicin, clindamycin, flagyl, ceftazidime",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Month to 18 Years"
      },
      "enrollment_count": 100,
      "start_date": "2005-04",
      "completion_date": "2007-01",
      "has_results": false,
      "last_update_posted_date": "2007-04-06",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00195923"
    },
    {
      "nct_id": "NCT00835458",
      "title": "Endoscopic Treatment of Intestinal Fistulas and Perforations",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastric Fistula"
      ],
      "interventions": [
        {
          "name": "gastro-gastric fistula closure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Legacy Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 5,
      "start_date": "2009-02",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2009-02-11",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00835458"
    },
    {
      "nct_id": "NCT00854815",
      "title": "Irrigation Versus No Irrigation for Perforated Appendicitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perforated Appendicitis"
      ],
      "interventions": [
        {
          "name": "Irrigation",
          "type": "PROCEDURE"
        },
        {
          "name": "No Irrigation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "1 Month to 17 Years"
      },
      "enrollment_count": 220,
      "start_date": "2008-12",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2012-08-01",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00854815"
    },
    {
      "nct_id": "NCT01306838",
      "title": "Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Short Bowel Syndrome",
        "Necrotizing Enterocolitis",
        "Small Intestine Perforation"
      ],
      "interventions": [
        {
          "name": "MicroLipid and fish oil",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Routine care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Wake Forest University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "60 Days",
        "sex": "ALL",
        "summary": "1 Day to 60 Days"
      },
      "enrollment_count": 40,
      "start_date": "2009-10",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2018-08-15",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01306838"
    },
    {
      "nct_id": "NCT02687464",
      "title": "Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Appendicitis"
      ],
      "interventions": [
        {
          "name": "Non-operative treatment",
          "type": "OTHER"
        },
        {
          "name": "Appendectomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "5 Years to 16 Years"
      },
      "enrollment_count": 978,
      "start_date": "2016-01-20",
      "completion_date": "2023-03-02",
      "has_results": false,
      "last_update_posted_date": "2023-12-26",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02687464"
    },
    {
      "nct_id": "NCT03795194",
      "title": "Antibiotic Duration in Post-appendectomy Abscess",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Complicated Appendicitis",
        "Perforated Appendicitis"
      ],
      "interventions": [
        {
          "name": "ampicillin/clavulanate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Phoenix Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Years to 17 Years"
      },
      "enrollment_count": 7,
      "start_date": "2019-05-01",
      "completion_date": "2021-12-15",
      "has_results": true,
      "last_update_posted_date": "2024-03-08",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03795194"
    },
    {
      "nct_id": "NCT03386136",
      "title": "Therapeutic Oxygen for Gastrointestinal Atony (TOGA)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ileus",
        "Ogilvie Syndrome",
        "Small Bowel Obstruction"
      ],
      "interventions": [
        {
          "name": "100% Oxygen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 17,
      "start_date": "2018-01-25",
      "completion_date": "2019-10-17",
      "has_results": false,
      "last_update_posted_date": "2019-12-12",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03386136"
    },
    {
      "nct_id": "NCT00195351",
      "title": "Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Appendicitis",
        "Cholecystitis",
        "Cross Infection",
        "Diverticulitis",
        "Peritonitis"
      ],
      "interventions": [
        {
          "name": "tigecycline",
          "type": "DRUG"
        },
        {
          "name": "ceftriaxone sodium + metronidazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wyeth is now a wholly owned subsidiary of Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 467,
      "start_date": "2005-09",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2013-02-25",
      "last_synced_at": "2026-05-22T06:54:53.161Z",
      "location_count": 46,
      "location_summary": "Mobile, Alabama • Laguna Hills, California • Los Angeles, California + 38 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Palm Springs",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00195351"
    }
  ]
}