{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Intracranial+Hypotension",
    "query": {
      "condition": "Intracranial Hypotension"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T02:29:40.204Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03996317",
      "title": "Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Perinatal Death",
        "Respiratory Distress Syndrome, Newborn",
        "Hypoxic-Ischemic Encephalopathy",
        "Neonatal Seizure",
        "Meconium Aspiration Syndrome",
        "Intracranial Hemorrhages",
        "Neonatal Hypotension"
      ],
      "interventions": [
        {
          "name": "Room air",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2021-06",
      "completion_date": "2022-12-30",
      "has_results": false,
      "last_update_posted_date": "2021-08-17",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03996317"
    },
    {
      "nct_id": "NCT03041441",
      "title": "Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intracranial Hypotension"
      ],
      "interventions": [
        {
          "name": "MRI algorithm",
          "type": "DEVICE"
        },
        {
          "name": "Lumbar puncture",
          "type": "PROCEDURE"
        },
        {
          "name": "Epidural patching",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2017-09-14",
      "completion_date": "2019-10-26",
      "has_results": true,
      "last_update_posted_date": "2020-07-28",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03041441"
    },
    {
      "nct_id": "NCT05922514",
      "title": "A Clinical Registry of Spontaneous Intracranial Hypotension",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spontaneous Intracranial Hypotension"
      ],
      "interventions": [
        {
          "name": "Transvenous Embolization of Cerebrospinal Fluid-Venous Fistula",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2023-06-18",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2025-12-03",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05922514"
    },
    {
      "nct_id": "NCT07582744",
      "title": "CVFs in SIH: EID vs. PCD CTM",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spontaneous Intracranial Hypotension"
      ],
      "interventions": [
        {
          "name": "photon counting detector CT myelography (PCD- CTM)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "energy integrating detector CT myelography (EID-CTM)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2026-05-21",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07582744"
    },
    {
      "nct_id": "NCT03276975",
      "title": "A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cerebrospinal Fluid Leaks"
      ],
      "interventions": [
        {
          "name": "TISSEEL",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2017-12-18",
      "completion_date": "2020-03-19",
      "has_results": true,
      "last_update_posted_date": "2021-06-18",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03276975"
    },
    {
      "nct_id": "NCT03276494",
      "title": "Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stroke",
        "Intracranial Hypotension",
        "Cerebral Edema"
      ],
      "interventions": [
        {
          "name": "Intraosseous",
          "type": "DEVICE"
        },
        {
          "name": "Hypertonic saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2017-04-21",
      "completion_date": "2018-04-21",
      "has_results": true,
      "last_update_posted_date": "2019-07-09",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03276494"
    },
    {
      "nct_id": "NCT00803036",
      "title": "Observational Study of Cortical Spreading Depression in Human Brain Trauma",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 165,
      "start_date": "2009-01",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2018-01-31",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 4,
      "location_summary": "Miami, Florida • Cincinnati, Ohio • Pittsburgh, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00803036"
    },
    {
      "nct_id": "NCT02795052",
      "title": "Neurologic Stem Cell Treatment Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurologic Disorders",
        "Nervous System Diseases",
        "Neurodegenerative Diseases",
        "Neurological Disorders",
        "Stroke",
        "Traumatic Brain Injury",
        "Cadasil",
        "Chronic Traumatic Encephalopathy",
        "Cerebral Infarction",
        "Cerebral Ischemia",
        "Cerebral Stroke",
        "Cerebral Hemorrhage",
        "Parkinson",
        "Multi-System Degeneration",
        "MSA - Multiple System Atrophy",
        "Progressive Supranuclear Palsy",
        "ALS",
        "Amyotrophic Lateral Sclerosis",
        "Neuropathy",
        "Diabetic Neuropathies",
        "Alzheimer Disease",
        "Dementia",
        "Frontotemporal Dementia",
        "Lewy Body Disease",
        "Cognitive Impairment",
        "Lewy Body Variant of Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Intravenous and Intranasal BMSC",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "MD Stem Cells",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2016-06",
      "completion_date": "2028-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-26",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 2,
      "location_summary": "Westport, Connecticut • Coral Springs, Florida",
      "locations": [
        {
          "city": "Westport",
          "state": "Connecticut"
        },
        {
          "city": "Coral Springs",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02795052"
    },
    {
      "nct_id": "NCT02603549",
      "title": "Pituitary Function and Spontaneous Intracranial Hypotension",
      "overall_status": "SUSPENDED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hyperprolactinemia",
        "Spontaneous Intracranial Hypotension"
      ],
      "interventions": [
        {
          "name": "Pituitary panel will be drawn pre-op and post-op for all patients.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2015-07",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2019-01-31",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02603549"
    },
    {
      "nct_id": "NCT00432536",
      "title": "Redesigning Cardiac Surgery to Reduce Neurologic Injury",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiovascular Disease",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Quality improvement intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "40 Years to 89 Years"
      },
      "enrollment_count": 469,
      "start_date": "2002-10",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2013-05-16",
      "last_synced_at": "2026-07-23T02:29:40.204Z",
      "location_count": 3,
      "location_summary": "Portland, Maine • Lebanon, New Hampshire • Manchester, New Hampshire",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "Manchester",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00432536"
    }
  ]
}