{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Intraoperative+Bleeding&page=4",
    "query": {
      "condition": "Intraoperative Bleeding",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 87,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Intraoperative+Bleeding&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Intraoperative+Bleeding&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T08:27:23.569Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02043132",
      "title": "Tranexamic Acid in Reverse Total Shoulder Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Shoulder Joint Disease",
        "Complications; Arthroplasty",
        "Intraoperative Complications",
        "Blood Loss, Surgical"
      ],
      "interventions": [
        {
          "name": "Tranexamic Acid",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Corewell Health East",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 116,
      "start_date": "2013-09",
      "completion_date": "2016-02",
      "has_results": true,
      "last_update_posted_date": "2017-06-19",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 1,
      "location_summary": "Royal Oak, Michigan",
      "locations": [
        {
          "city": "Royal Oak",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02043132"
    },
    {
      "nct_id": "NCT05093504",
      "title": "Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemorrhage, Surgical",
        "Hemorrhage Postoperative",
        "Blood Loss, Surgical",
        "Blood Loss, Postoperative"
      ],
      "interventions": [
        {
          "name": "Sham comparator",
          "type": "DEVICE"
        },
        {
          "name": "DrugSorb-ATR system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CytoSorbents, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2021-12-27",
      "completion_date": "2024-01-29",
      "has_results": true,
      "last_update_posted_date": "2025-05-04",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 27,
      "location_summary": "Sacramento, California • Denver, Colorado • New Haven, Connecticut + 22 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05093504"
    },
    {
      "nct_id": "NCT00708513",
      "title": "Intraoperative Cell Saver Autotransfusion Use for Major Surgical Oncology Operations.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pancreaticoduodenectomy",
        "Pancreatectomy",
        "Esophagectomy",
        "Gastrectomy",
        "Hepatectomy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 98,
      "start_date": "2003-12",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2013-10-21",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 2,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00708513"
    },
    {
      "nct_id": "NCT01634828",
      "title": "Method for Improved Intraoperative Blood Loss Estimates",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Improved Intraoperative Blood Loss Estimates"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 47,
      "start_date": "2012-07",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2016-05-12",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01634828"
    },
    {
      "nct_id": "NCT00306137",
      "title": "Study to Investigate the Effect of Aprotinin of Transfusion Requirements in Patients Undergoing Surgical Procedures for Lung or Esophageal Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Blood Loss, Surgical"
      ],
      "interventions": [
        {
          "name": "Trasylol (Aprotinin, BAYA0128)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2005-12",
      "completion_date": "2007-03",
      "has_results": false,
      "last_update_posted_date": "2014-12-09",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 12,
      "location_summary": "Atlanta, Georgia • Augusta, Georgia • Indianapolis, Indiana + 8 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00306137"
    },
    {
      "nct_id": "NCT01583465",
      "title": "Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Hip",
        "Joint Deformities, Acquired",
        "Hip Dislocation, Congenital",
        "Osteonecrosis",
        "Arthritis, Rheumatoid"
      ],
      "interventions": [
        {
          "name": "Aquamantys",
          "type": "DEVICE"
        },
        {
          "name": "standard electrocautery (Bovie)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Joint Implant Surgeons, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 200,
      "start_date": "2009-10",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2012-04-24",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 1,
      "location_summary": "New Albany, Ohio",
      "locations": [
        {
          "city": "New Albany",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01583465"
    },
    {
      "nct_id": "NCT02032030",
      "title": "Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Attack",
        "Cardiac Arrest",
        "Congestive Heart Failure",
        "Atrial Fibrillation",
        "Angina",
        "Deep Vein Thrombosis",
        "Pulmonary Embolism",
        "Respiratory Arrest",
        "Respiratory Failure",
        "Pneumonia",
        "Gastrointestinal Bleed",
        "Stomach Ulcer",
        "Delirium",
        "Stroke",
        "Nerve Injury",
        "Surgical Wound Infection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 73952,
      "start_date": "2012-07",
      "completion_date": "2020-10-21",
      "has_results": false,
      "last_update_posted_date": "2022-08-09",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02032030"
    },
    {
      "nct_id": "NCT07826637",
      "title": "Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blood Loss, Surgical",
        "Postoperative Hemorrhage"
      ],
      "interventions": [
        {
          "name": "Wearable optical hemodynamic monitoring device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Hemorai Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 80,
      "start_date": "2026-10-15",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-22",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 1,
      "location_summary": "Burlington, Massachusetts",
      "locations": [
        {
          "city": "Burlington",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07826637"
    },
    {
      "nct_id": "NCT05258487",
      "title": "The Utility of the Validated Intraoperative Bleeding Scale in Spine Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intraoperative Blood Loss",
        "Thoracolumbar Spine Surgery"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "88 Years",
        "sex": "ALL",
        "summary": "18 Years to 88 Years"
      },
      "enrollment_count": 121,
      "start_date": "2022-03-01",
      "completion_date": "2023-03-14",
      "has_results": false,
      "last_update_posted_date": "2024-05-13",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05258487"
    },
    {
      "nct_id": "NCT05047133",
      "title": "Effect of Early Administration of TXA in Adult Hip Fractures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Postoperative Blood Loss"
      ],
      "interventions": [
        {
          "name": "Tranexamic acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ascension Health",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 170,
      "start_date": "2021-09-01",
      "completion_date": "2022-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-09-16",
      "last_synced_at": "2026-10-22T08:27:23.569Z",
      "location_count": 1,
      "location_summary": "Grand Blanc, Michigan",
      "locations": [
        {
          "city": "Grand Blanc",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05047133"
    }
  ]
}