{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Iron+Overload&page=2",
    "query": {
      "condition": "Iron Overload",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Iron+Overload&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:02:52.404Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02308904",
      "title": "Reproductive Capacity and Iron Burden in Thalassemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "THALASSEMIA MAJOR"
      ],
      "interventions": [
        {
          "name": "Blood Draw/Semen Exam",
          "type": "OTHER"
        },
        {
          "name": "Retrospective data/Chart Review/Relevant Clinical Results",
          "type": "OTHER"
        },
        {
          "name": "Pituitary MRI",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UCSF Benioff Children's Hospital Oakland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 59,
      "start_date": "2013-06-01",
      "completion_date": "2020-09-01",
      "has_results": false,
      "last_update_posted_date": "2020-12-23",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 1,
      "location_summary": "Oakland, California",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02308904"
    },
    {
      "nct_id": "NCT04631718",
      "title": "MRI QSM Imaging for Iron Overload",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hemochromatosis",
        "Iron Overload"
      ],
      "interventions": [
        {
          "name": "Magnetic Resonance Imaging (MRI)-based Quantitative Susceptibility Mapping (QSM)",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2022-01-18",
      "completion_date": "2024-04-29",
      "has_results": false,
      "last_update_posted_date": "2024-05-09",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 2,
      "location_summary": "Stanford, California • Madison, Wisconsin",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04631718"
    },
    {
      "nct_id": "NCT02007746",
      "title": "Liver Fibrosis in Sickle Cell Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sickle Cell Disease"
      ],
      "interventions": [
        {
          "name": "Liver transient elastography (Fibroscan)",
          "type": "OTHER"
        },
        {
          "name": "Ferriscan",
          "type": "OTHER"
        },
        {
          "name": "Liver biopsy in iron overloaded subjects.",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "10 Years to 65 Years"
      },
      "enrollment_count": 26,
      "start_date": "2012-07",
      "completion_date": "2017-06-01",
      "has_results": false,
      "last_update_posted_date": "2021-05-26",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02007746"
    },
    {
      "nct_id": "NCT00806715",
      "title": "Iron Overload in Stem Cell Transplant Recipients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Iron Overload"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2007-02",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2018-03-26",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00806715"
    },
    {
      "nct_id": "NCT01516853",
      "title": "Non-invasive Quantification of Liver Iron With MRI",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Iron Overload",
        "Hemosiderosis"
      ],
      "interventions": [
        {
          "name": "Non-contrast MRI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "10 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2012-01",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2019-12-06",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01516853"
    },
    {
      "nct_id": "NCT00901199",
      "title": "Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Thalassemia",
        "Iron Overload"
      ],
      "interventions": [
        {
          "name": "Combo Chelation with Deferasirox (Exjade) and Deferoxamine (DFO)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Elliott Vichinsky",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2007-09",
      "completion_date": "2012-10",
      "has_results": true,
      "last_update_posted_date": "2021-08-12",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 1,
      "location_summary": "Oakland, California",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00901199"
    },
    {
      "nct_id": "NCT04018300",
      "title": "Iron Supplementation and Side Effects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Iron Deficiency Anemia",
        "Iron Overload"
      ],
      "interventions": [
        {
          "name": "Ferrous sulfate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Aspiron",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Iowa State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 17,
      "start_date": "2018-01-08",
      "completion_date": "2018-04-18",
      "has_results": false,
      "last_update_posted_date": "2019-07-12",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 1,
      "location_summary": "Ames, Iowa",
      "locations": [
        {
          "city": "Ames",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04018300"
    },
    {
      "nct_id": "NCT00000623",
      "title": "Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anemia, Cooley's",
        "Beta-Thalassemia",
        "Hematologic Diseases",
        "Thalassemia",
        "Osteoporosis",
        "Iron Overload",
        "Hypertension, Pulmonary"
      ],
      "interventions": [
        {
          "name": "Deferoxamine",
          "type": "DRUG"
        },
        {
          "name": "Deferiprone",
          "type": "DRUG"
        },
        {
          "name": "Arginine",
          "type": "DRUG"
        },
        {
          "name": "Sildenafil",
          "type": "DRUG"
        },
        {
          "name": "Decitabine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Carelon Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "1 Year to 75 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2000-07",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2014-03-04",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 4,
      "location_summary": "Oakland, California • Boston, Massachusetts • New York, New York + 1 more",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000623"
    },
    {
      "nct_id": "NCT00061750",
      "title": "Safety & Efficacy of ICL670 vs. Deferoxamine in Beta-thalassemia Patients With Iron Overload Due to Blood Transfusions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Beta-Thalassemia"
      ],
      "interventions": [
        {
          "name": "ICL670",
          "type": "DRUG"
        },
        {
          "name": "deferoxamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 595,
      "start_date": "2003-05",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2012-04-19",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 7,
      "location_summary": "Los Angeles, California • Oakland, California • Stanford, California + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00061750"
    },
    {
      "nct_id": "NCT01114776",
      "title": "Multi-Center Study of Iron Overload: Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sickle Cell Disease",
        "Thalassemia",
        "Diamond-Blackfan Anemia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "UCSF Benioff Children's Hospital Oakland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2009-11-01",
      "completion_date": "2013-09-30",
      "has_results": false,
      "last_update_posted_date": "2020-09-24",
      "last_synced_at": "2026-05-22T07:02:52.404Z",
      "location_count": 1,
      "location_summary": "Oakland, California",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01114776"
    }
  ]
}