{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ischemic-Hypoxic+Encephalopathy&page=3",
    "query": {
      "condition": "Ischemic-Hypoxic Encephalopathy",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 75,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ischemic-Hypoxic+Encephalopathy&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ischemic-Hypoxic+Encephalopathy&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T03:21:08.830Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02260271",
      "title": "Florida Neonatal Neurologic Network",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxic-Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Database Entry/Biospecimen Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "3 Weeks",
        "sex": "ALL",
        "summary": "1 Day to 3 Weeks"
      },
      "enrollment_count": 1000,
      "start_date": "2011-09-09",
      "completion_date": "2045-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-11",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02260271"
    },
    {
      "nct_id": "NCT07275021",
      "title": "Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in Neonates",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preterm Less Than 32wks With IVH, WMI/PVL",
        "Late Preterm or Term (37-42wks) With Neonatal Encephalopathy Treated With Hypothermia for HIE"
      ],
      "interventions": [
        {
          "name": "Prospective Clinical and Neurodevelopmental Data Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "31 Weeks",
        "maximum_age": "42 Weeks",
        "sex": "ALL",
        "summary": "31 Weeks to 42 Weeks"
      },
      "enrollment_count": 60,
      "start_date": "2025-07-07",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-10",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07275021"
    },
    {
      "nct_id": "NCT00830531",
      "title": "Pilot Study of Bumetanide for Newborn Seizures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Seizures"
      ],
      "interventions": [
        {
          "name": "Bumetanide",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline as Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Soul, Janet , M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "44 Weeks",
        "sex": "ALL",
        "summary": "Up to 44 Weeks"
      },
      "enrollment_count": 43,
      "start_date": "2010-01",
      "completion_date": "2019-01",
      "has_results": false,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 4,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00830531"
    },
    {
      "nct_id": "NCT01904786",
      "title": "Melatonin Treatment for Newborn Infants With Moderate to Severe Hypoxic Ischemic Encephalopathy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Newborn Hypoxic Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Melatonin",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "8 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 8 Hours"
      },
      "enrollment_count": 0,
      "start_date": "2014-04",
      "completion_date": "2018-11",
      "has_results": false,
      "last_update_posted_date": "2015-07-03",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01904786"
    },
    {
      "nct_id": "NCT03835039",
      "title": "The Ability of NIRS to Predict Brain Injury in Hypoxic Ischemic Encephalopathy",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "HIE - Perinatal Hypoxic - Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "NIRS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "1 Minute to 2 Years"
      },
      "enrollment_count": 101,
      "start_date": "2019-01-03",
      "completion_date": "2022-01-01",
      "has_results": false,
      "last_update_posted_date": "2022-03-15",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03835039"
    },
    {
      "nct_id": "NCT02983786",
      "title": "Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Traumatic Brain Injury",
        "Ischemic Stroke",
        "Intracerebral Hemorrhage",
        "Subarachnoid Hemorrhage",
        "Acute Anoxic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Indocyanine Green",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2015-12",
      "completion_date": "2022-05-25",
      "has_results": false,
      "last_update_posted_date": "2022-09-02",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02983786"
    },
    {
      "nct_id": "NCT07857070",
      "title": "Newborn Brain Assessment - CergenX Wave",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neonatal Encephalopathy",
        "Neonatal Encephalopathy (Neonatal Hypoxic-ischemic Encephalopathy)",
        "Neonatal Encephalopathy, Unspecified"
      ],
      "interventions": [
        {
          "name": "CergenX Wave",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CergenX Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "36 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "36 Weeks and older"
      },
      "enrollment_count": 165,
      "start_date": "2026-09",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-10-05",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07857070"
    },
    {
      "nct_id": "NCT02264808",
      "title": "Developmental Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxic-Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Developmental Outcomes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Months",
        "maximum_age": "20 Months",
        "sex": "ALL",
        "summary": "18 Months to 20 Months"
      },
      "enrollment_count": 21,
      "start_date": "2014-11",
      "completion_date": "2018-12-03",
      "has_results": false,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02264808"
    },
    {
      "nct_id": "NCT05851391",
      "title": "buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hypoxia-Ischemia, Brain",
        "Heart Arrest",
        "Status Epilepticus",
        "Refractory Status Epilepticus",
        "Seizures",
        "Anoxic-Ischemic Encephalopathy",
        "Anoxia-Ischemia, Cerebral"
      ],
      "interventions": [
        {
          "name": "Burst Suppression EEG Target Intravenous Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "Seizure Suppression EEG Target Intravenous Anesthesia",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2023-08-07",
      "completion_date": "2028-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05851391"
    },
    {
      "nct_id": "NCT04602325",
      "title": "Systemic Biomarkers of Brain Injury From Hyperammonemia",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Urea Cycle Disorder",
        "Organic Acidemia",
        "Maple Syrup Urine Disease",
        "Glutaric Acidemia I",
        "Fatty Acid Oxidation Disorder",
        "Hypoxic-Ischemic Encephalopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "7 Years to 18 Years"
      },
      "enrollment_count": 24,
      "start_date": "2020-07-09",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2024-02-07",
      "last_synced_at": "2026-10-08T03:21:08.830Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04602325"
    }
  ]
}