{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Joint+Damage", "query": { "condition": "Joint Damage" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 39, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Joint+Damage&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-23T05:25:32.219Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03262909", "title": "Pivotal Study to Evaluate the Safety and Efficacy of GelrinC for Treatment of Cartilage Defects", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Articular Cartilage Defects in the Knee Joint" ], "interventions": [ { "name": "GelrinC", "type": "DEVICE" }, { "name": "Microfracture historical control arm", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Regentis Biomaterials", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 181, "start_date": "2017-11-14", "completion_date": "2024-11", "has_results": false, "last_update_posted_date": "2022-03-22", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 13, "location_summary": "La Mesa, California • Orange, California • Denver, Colorado + 10 more", "locations": [ { "city": "La Mesa", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Gulf Breeze", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03262909" }, { "nct_id": "NCT00548119", "title": "NeoCart Phase 2 Clinical Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Articular Cartilage Damage" ], "interventions": [ { "name": "NeoCart", "type": "BIOLOGICAL" }, { "name": "microfracture", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "PROCEDURE" ], "sponsor": "Histogenics Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 30, "start_date": "2006-12", "completion_date": "2014-03", "has_results": false, "last_update_posted_date": "2014-04-21", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 6, "location_summary": "San Francisco, California • Bloomington, Minnesota • New York, New York + 3 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Bloomington", "state": "Minnesota" }, { "city": "New York", "state": "New York" }, { "city": "West Point", "state": "New York" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00548119" }, { "nct_id": "NCT00820430", "title": "MRI Markers of Cartilage Damage in Knee With Osteoarthritis", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Osteoarthritis, Knee" ], "interventions": [ { "name": "Magnetic Resonance Imaging", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "American College of Radiology", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 53, "start_date": "2006-11", "completion_date": "2008-05", "has_results": false, "last_update_posted_date": "2023-07-20", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 5, "location_summary": "Hershey, Pennsylvania • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania", "locations": [ { "city": "Hershey", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00820430" }, { "nct_id": "NCT00286689", "title": "Effects of Growth Hormone in Chronically Ill Children", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hurler Syndrome", "Cerebral Palsy", "Juvenile Rheumatoid Arthritis", "Crohn Disease", "HIV Infections" ], "interventions": [ { "name": "Growth Hormone", "type": "DRUG" }, { "name": "Whole body Protein turnover", "type": "PROCEDURE" }, { "name": "DEXA scan", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "3 Years to 17 Years" }, "enrollment_count": 0, "start_date": "2006-02-03", "completion_date": "2006-02-03", "has_results": false, "last_update_posted_date": "2018-12-14", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00286689" }, { "nct_id": "NCT07478679", "title": "Radiation to Treat Joint Damage Caused by Cancer Immunotherapy", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Arthritis", "Arthropathy" ], "interventions": [ { "name": "Low dose radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "RADIATION" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 20, "start_date": "2026-08-26", "completion_date": "2028-09-17", "has_results": false, "last_update_posted_date": "2026-03-23", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT07478679" }, { "nct_id": "NCT01717846", "title": "Effect on Orencia (Abatacept) on the Apoptosis of T Cells, B Cells and APC Cells in Rheumatoid Arthritis", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Apoptotic DNA Damage", "Rheumatoid Arthritis", "T-cell Lymphocytosis" ], "interventions": [ { "name": "Group 1 or Orencia treated group", "type": "DRUG" }, { "name": "Group 2 (DMARDS treated group)", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 0, "start_date": "2012-12", "completion_date": "2014-11", "has_results": false, "last_update_posted_date": "2016-05-11", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01717846" }, { "nct_id": "NCT01105546", "title": "rFVIIa Prophylaxis in Children With Hemophilia A and Inhibitors", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hemophilia A With Inhibitors" ], "interventions": [ { "name": "recombinant activated factor VII", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "8 Years", "sex": "MALE", "summary": "Up to 8 Years · Male only" }, "enrollment_count": 50, "start_date": "2010-12", "completion_date": "2014-04", "has_results": false, "last_update_posted_date": "2013-04-08", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 3, "location_summary": "Los Angeles, California • Atlanta, Georgia • Kansas City, Missouri", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Kansas City", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01105546" }, { "nct_id": "NCT02469662", "title": "Clinical Outcomes Study of the Nexel Total Elbow", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Elbow Joint Destruction", "Post-traumatic Lesions", "Ankylosed Joints", "Advanced Rheumatoid Arthritis", "Joint Instability or Loss of Motion", "Acute Comminuted Articular Fracture of Elbow Joint Surfaces", "Bone Loss Contributing to Elbow Instability", "Bilateral Ankylosis From Causes Other Than Active Sepsis", "Post-traumatic Arthritis", "Degenerative Arthritis" ], "interventions": [ { "name": "Nexel Total Elbow", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Zimmer Biomet", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 134, "start_date": "2015-06", "completion_date": "2036-12", "has_results": false, "last_update_posted_date": "2026-07-09", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 4, "location_summary": "Golden, Colorado • Charlotte, North Carolina • Philadelphia, Pennsylvania + 1 more", "locations": [ { "city": "Golden", "state": "Colorado" }, { "city": "Charlotte", "state": "North Carolina" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Germantown", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02469662" }, { "nct_id": "NCT00160641", "title": "A Study of the Safety and Effectiveness of Liquid Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Certolizumab Pegol", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "UCB Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 567, "start_date": "2005-11", "completion_date": "2012-02", "has_results": true, "last_update_posted_date": "2020-03-27", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 12, "location_summary": "Palm Desert, California • Pasadena, California • Santa Maria, California + 9 more", "locations": [ { "city": "Palm Desert", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Santa Maria", "state": "California" }, { "city": "Whittier", "state": "California" }, { "city": "Naples", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00160641" }, { "nct_id": "NCT06583395", "title": "Quest to Analyze One Thousand Humans Meditating", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Amyotrophic Lateral Sclerosis (ALS)", "Angina, Stable", "Anxiety", "Asthma", "Atrial Fibrillation", "Cancer Brain", "Cancer, Breast", "Cancer Colon", "Cancer, Lung", "Cancer, Ovarian", "Cancer Prostate", "Cancer Skin", "Throat Cancer", "Lymphoma", "Cancer, Thyroid", "Cancer, Other", "Cerebral Palsy", "Chronic Fatigue Syndrome", "Cluster Headache", "Chronic Obstructive Pulmonary Disease (COPD)", "Chronic Kidney Diseases", "Crohn Disease", "Deafness", "Depression", "Diabetes", "Eczema", "Epilepsy", "Fibroids", "Fibromyalgia", "Heart Failure", "Hypertension", "Hyperthyroidism", "Hypothyroidism", "Irritable Bowel Syndrome (IBS)", "Infertility", "Lyme Disease", "Macular Degeneration", "Migraine", "Multiple Allergies", "Multiple Sclerosis", "Osteoarthritis", "Osteoporosis", "Ovarian Cysts", "Parkinson Disease", "Phantom Limb Pain", "Psoriasis", "Post Traumatic Stress Disorder (PTSD)", "Rheumatoid Arthritis", "Sjogrens Disease", "Spinal Cord Injury", "Spinal Stenosis", "Stroke", "Tension Headache", "Tinnitus", "Ulcerative Colitis" ], "interventions": [ { "name": "Advanced multi-component meditation practice", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Tobias Moeller-Bertram", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 3000, "start_date": "2021-12-05", "completion_date": "2025-03-25", "has_results": false, "last_update_posted_date": "2024-11-01", "last_synced_at": "2026-07-23T05:25:32.219Z", "location_count": 1, "location_summary": "Palm Desert, California", "locations": [ { "city": "Palm Desert", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06583395" } ] }