{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Kaposiform+Hemangioendotheliomas",
    "query": {
      "condition": "Kaposiform Hemangioendotheliomas"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T02:12:10.284Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00975819",
      "title": "Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Kaposiform Hemangioendotheliomas",
        "Tufted Angioma",
        "Capillary Venous Lymphatic Malformation",
        "Venous Lymphatic Malformation",
        "Microcystic Lymphatic Malformation",
        "Mucocutaneous Lymphangiomatosis and Thrombocytopenia",
        "Capillary Lymphatic Arterial Venous Malformations",
        "PTEN Overgrowth Syndrome With Vascular Anomaly",
        "Lymphangiectasia Syndromes"
      ],
      "interventions": [
        {
          "name": "sirolimus",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Denise Martin Adams",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "31 Years",
        "sex": "ALL",
        "summary": "Up to 31 Years"
      },
      "enrollment_count": 61,
      "start_date": "2009-10",
      "completion_date": "2020-10",
      "has_results": true,
      "last_update_posted_date": "2026-01-06",
      "last_synced_at": "2026-05-22T02:12:10.284Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00975819"
    },
    {
      "nct_id": "NCT02110069",
      "title": "A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Kaposiform Hemangioendothelioma (KHE)",
        "Kasabach-Merritt Syndrome",
        "Tufted Angioma"
      ],
      "interventions": [
        {
          "name": "Vincristine",
          "type": "DRUG"
        },
        {
          "name": "Sirolimus",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "31 Years",
        "sex": "ALL",
        "summary": "Up to 31 Years"
      },
      "enrollment_count": 4,
      "start_date": "2017-06-14",
      "completion_date": "2020-10-27",
      "has_results": true,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-05-22T02:12:10.284Z",
      "location_count": 7,
      "location_summary": "Palo Alto, California • Atlanta, Georgia • Baltimore, Maryland + 4 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02110069"
    },
    {
      "nct_id": "NCT03001180",
      "title": "Identification of Biomarkers for Patients with Vascular Anomalies",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Vascular Anomaly",
        "Generalized Lymphatic Anomaly",
        "Kaposiform Hemangioendothelioma",
        "Kaposiform Lymphangiomatosis",
        "Gorham-Stout Disease",
        "Klippel Trenaunay Syndrome",
        "Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Day and older"
      },
      "enrollment_count": 1000,
      "start_date": "2015-04",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2024-11-06",
      "last_synced_at": "2026-05-22T02:12:10.284Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03001180"
    },
    {
      "nct_id": "NCT02399527",
      "title": "Lymphatic Anomalies Registry for the Assessment of Outcome Data",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphatic Malformation",
        "Generalized Lymphatic Anomaly (GLA)",
        "Central Conducting Lymphatic Anomaly",
        "CLOVES Syndrome",
        "Gorham-Stout Disease (\"Disappearing Bone Disease\")",
        "Blue Rubber Bleb Nevus Syndrome",
        "Kaposiform Lymphangiomatosis",
        "Kaposiform Hemangioendothelioma/Tufted Angioma",
        "Klippel-Trenaunay Syndrome",
        "Lymphangiomatosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2013-06",
      "completion_date": "2035-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-22T02:12:10.284Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02399527"
    }
  ]
}