{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Keratoplasty%2C+Lamellar",
    "query": {
      "condition": "Keratoplasty, Lamellar"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T05:22:03.391Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01901614",
      "title": "OCT-guided LALAK for KCN",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Corneal Opacity",
        "Keratoconus"
      ],
      "interventions": [
        {
          "name": "LALAK",
          "type": "PROCEDURE"
        },
        {
          "name": "IEK",
          "type": "PROCEDURE"
        },
        {
          "name": "Retrobulbar Block or General Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "optical coherence tomography (OCT)",
          "type": "DEVICE"
        },
        {
          "name": "Topical Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "femtosecond laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 5,
      "start_date": "2013-08",
      "completion_date": "2017-08-31",
      "has_results": true,
      "last_update_posted_date": "2019-01-23",
      "last_synced_at": "2026-07-24T05:22:03.391Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01901614"
    },
    {
      "nct_id": "NCT02373137",
      "title": "Descemet Endothelial Thickness Comparison Trial",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Keratoplasty",
        "Grafting, Corneal",
        "Transplantation, Corneal",
        "Transplantation, Cornea",
        "Keratoplasty, Lamellar"
      ],
      "interventions": [
        {
          "name": "DSAEK",
          "type": "PROCEDURE"
        },
        {
          "name": "DMEK",
          "type": "PROCEDURE"
        },
        {
          "name": "Endoserter",
          "type": "DEVICE"
        },
        {
          "name": "Prednisolone",
          "type": "DRUG"
        },
        {
          "name": "Ofloxacin",
          "type": "DRUG"
        },
        {
          "name": "Tropicamide",
          "type": "DRUG"
        },
        {
          "name": "Phenylephrine",
          "type": "DRUG"
        },
        {
          "name": "Jones Tube",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2015-01-22",
      "completion_date": "2023-05-30",
      "has_results": true,
      "last_update_posted_date": "2020-11-25",
      "last_synced_at": "2026-07-24T05:22:03.391Z",
      "location_count": 3,
      "location_summary": "Palo Alto, California • San Francisco, California • Portland, Oregon",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02373137"
    },
    {
      "nct_id": "NCT01579643",
      "title": "OCT-guided LALAK in Children",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Corneal Opacity"
      ],
      "interventions": [
        {
          "name": "OCT guided laser-assisted lamellar anterior keratoplasty (LALAK)",
          "type": "PROCEDURE"
        },
        {
          "name": "Penetrating Keratoplasty (KP)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Month to 18 Years"
      },
      "enrollment_count": 1,
      "start_date": "2012-01",
      "completion_date": "2016-08-31",
      "has_results": false,
      "last_update_posted_date": "2018-04-17",
      "last_synced_at": "2026-07-24T05:22:03.391Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01579643"
    },
    {
      "nct_id": "NCT00345020",
      "title": "Deep Lamellar Endothelial Keratoplasty: Small Incision Technique",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Corneal Transplantation"
      ],
      "interventions": [
        {
          "name": "Deep Lamellar Endothelial Keratoplasty: Small Incision Technique",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "21 Years to 95 Years"
      },
      "enrollment_count": 0,
      "start_date": "2006-05",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2018-08-15",
      "last_synced_at": "2026-07-24T05:22:03.391Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00345020"
    },
    {
      "nct_id": "NCT00346138",
      "title": "A Comparison Between Full Thickness and Partial Thickness Corneal Transplantation for Corneal Edema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fuchs Dystrophy",
        "Corneal Edema"
      ],
      "interventions": [
        {
          "name": "Corneal transplantation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2005-06",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2010-01-15",
      "last_synced_at": "2026-07-24T05:22:03.391Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00346138"
    },
    {
      "nct_id": "NCT04584125",
      "title": "A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Keratoconus"
      ],
      "interventions": [
        {
          "name": "Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% with UV light",
          "type": "DRUG"
        },
        {
          "name": "Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% without UV light",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Joseph B. Ciolino, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 216,
      "start_date": "2027-01-01",
      "completion_date": "2028-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-07-24T05:22:03.391Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04584125"
    }
  ]
}