{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Kidney+Replacement",
    "query": {
      "condition": "Kidney Replacement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 106,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Kidney+Replacement&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:44:30.112Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00343577",
      "title": "Antiproteinuric Agents and Fabry Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fabry Disease",
        "Proteinuria"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "14 Years to 95 Years"
      },
      "enrollment_count": 12,
      "start_date": "2001-01",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2013-11-19",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00343577"
    },
    {
      "nct_id": "NCT03368183",
      "title": "Acute Kidney Injury Standardized Clinical Assessment and Management Plan for Renal Replacement Initiation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "Care delivery algorithim",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 224,
      "start_date": "2017-07-01",
      "completion_date": "2022-02-28",
      "has_results": false,
      "last_update_posted_date": "2022-08-10",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03368183"
    },
    {
      "nct_id": "NCT05287204",
      "title": "Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Kidney Injury",
        "Critical Illness Myopathy",
        "Dialysis; Complications"
      ],
      "interventions": [
        {
          "name": "Musculoskeletal ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Assessments of muscle strength and physical function",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Metabolomics",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-11-29",
      "completion_date": "2024-12-30",
      "has_results": false,
      "last_update_posted_date": "2024-03-28",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 3,
      "location_summary": "Iowa City, Iowa • Lexington, Kentucky • Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05287204"
    },
    {
      "nct_id": "NCT05161078",
      "title": "Improving Continuous Renal Replacement Therapy Outcomes in Neonates and Infants Through Interdisciplinary Collaboration",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Kidney Injury",
        "Chronic Kidney Diseases",
        "Renal Dialysis"
      ],
      "interventions": [
        {
          "name": "CARPEDIEM",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2021-12-16",
      "completion_date": "2031-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 9,
      "location_summary": "Palo Alto, California • Aurora, Colorado • Atlanta, Georgia + 6 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05161078"
    },
    {
      "nct_id": "NCT05228132",
      "title": "The Pristine Post-Market Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Failure, Chronic",
        "Hemodialysis Complication",
        "Hemodialysis Catheter Infection",
        "Hemodialysis Access Failure",
        "Central Venous Catheter Related Bloodstream Infection",
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Pristine™ Long-Term Hemodialysis Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "C. R. Bard",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 142,
      "start_date": "2022-05-16",
      "completion_date": "2022-09-21",
      "has_results": true,
      "last_update_posted_date": "2024-04-11",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 6,
      "location_summary": "Dothan, Alabama • New Haven, Connecticut • Shreveport, Louisiana + 3 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05228132"
    },
    {
      "nct_id": "NCT01405092",
      "title": "Continuous Versus Conventional Volume Management During CRRT (Continuous Renal Replacement Therapy)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Continuous Renal Replacement Therapy"
      ],
      "interventions": [
        {
          "name": "use of continuous renal replacement machine for renal replacement",
          "type": "DEVICE"
        },
        {
          "name": "use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Dallas VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2010-04",
      "completion_date": "2012-08",
      "has_results": false,
      "last_update_posted_date": "2012-08-08",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01405092"
    },
    {
      "nct_id": "NCT00855127",
      "title": "New Urine and Blood Markers for Acute Kidney Injury in Liver Transplant Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Renal Insufficiency, Acute"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 0,
      "start_date": "2009-01",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2015-06-01",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • Seattle, Washington",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00855127"
    },
    {
      "nct_id": "NCT01072682",
      "title": "Safety Study of a Selective Cytopheretic Device (SCD) in Patients With Acute Renal Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Renal Failure"
      ],
      "interventions": [
        {
          "name": "Selective cytopheretic device (SCD)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "SeaStar Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 35,
      "start_date": "2010-02",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2022-03-31",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 7,
      "location_summary": "Birmingham, Alabama • San Diego, California • Denver, Colorado + 4 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01072682"
    },
    {
      "nct_id": "NCT01950819",
      "title": "Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "End Stage Renal Disease (ESRD)",
        "Chronic Kidney Disease (CKD)",
        "Hemodialysis",
        "Renal Replacement Therapy",
        "Renal Transplantation"
      ],
      "interventions": [
        {
          "name": "Induction therapy",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Corticosteroids",
          "type": "DRUG"
        },
        {
          "name": "EVR+rCNI",
          "type": "DRUG"
        },
        {
          "name": "MPA+sCNI",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2037,
      "start_date": "2013-12-03",
      "completion_date": "2018-01-17",
      "has_results": true,
      "last_update_posted_date": "2019-01-30",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 40,
      "location_summary": "Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 32 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01950819"
    },
    {
      "nct_id": "NCT04193865",
      "title": "Hemofilter Life Span, ECLS And/or CRRT",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Kidney Diseases",
        "Acute Injury of Kidney",
        "Renal Failure",
        "Renal Insufficiency",
        "Neonatal Renal Disorder (Disorder)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "0 Days to 17 Years"
      },
      "enrollment_count": 10,
      "start_date": "2020-01-09",
      "completion_date": "2024-03-25",
      "has_results": false,
      "last_update_posted_date": "2024-10-28",
      "last_synced_at": "2026-05-22T06:44:30.112Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04193865"
    }
  ]
}