{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Arthroplasty%2C+Total&page=2",
    "query": {
      "condition": "Knee Arthroplasty, Total",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Arthroplasty%2C+Total&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T11:35:23.824Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03378557",
      "title": "Periprosthetic Fracture Registry (PPFx)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periprosthetic Fractures",
        "Periprosthetic Fracture Around Prosthetic Joint Implant"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "AO Innovation Translation Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2018-12-31",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-12",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 4,
      "location_summary": "Columbia, Missouri • Jersey City, New Jersey • Livingston, New Jersey + 1 more",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "Jersey City",
          "state": "New Jersey"
        },
        {
          "city": "Livingston",
          "state": "New Jersey"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03378557"
    },
    {
      "nct_id": "NCT01184196",
      "title": "ChloraPrep Versus Betadine for Elective Knee Replacement Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Arthroplasty, Knee Replacement",
        "Replacement, Total Knee",
        "Total Knee Replacement"
      ],
      "interventions": [
        {
          "name": "Swab area with Betadine",
          "type": "DRUG"
        },
        {
          "name": "Swab area with ChloraPrep",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Central DuPage Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 55,
      "start_date": "2009-11",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2013-04-16",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 1,
      "location_summary": "Winfield, Illinois",
      "locations": [
        {
          "city": "Winfield",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01184196"
    },
    {
      "nct_id": "NCT05788757",
      "title": "Optetrak Knee System Post Market Clinical Follow-Up",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Arthroplasty, Total"
      ],
      "interventions": [
        {
          "name": "Optetrak Total Knee System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Exactech",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4588,
      "start_date": "2011-06-01",
      "completion_date": "2034-06-01",
      "has_results": false,
      "last_update_posted_date": "2024-06-18",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 3,
      "location_summary": "Worcester, Massachusetts • Las Vegas, Nevada • Charleston, South Carolina",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05788757"
    },
    {
      "nct_id": "NCT03016078",
      "title": "Self-adherent Absorbent Silver Dressing in Adults After Hip or Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasties, Hip Replacement",
        "Arthroplasties, Knee Replacement"
      ],
      "interventions": [
        {
          "name": "Mepilex Border Post-Op Ag",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Molnlycke Health Care AB",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2017-02-01",
      "completion_date": "2017-04-07",
      "has_results": true,
      "last_update_posted_date": "2018-02-14",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 1,
      "location_summary": "Gilbert, Arizona",
      "locations": [
        {
          "city": "Gilbert",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03016078"
    },
    {
      "nct_id": "NCT06460350",
      "title": "NEUROCUPLE™ in TKA Patients to Enhance Pain Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "NEUROCUPLE™ Patch",
          "type": "DEVICE"
        },
        {
          "name": "Placebo Patch",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "nCap Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 156,
      "start_date": "2024-09-25",
      "completion_date": "2025-07-18",
      "has_results": true,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06460350"
    },
    {
      "nct_id": "NCT05693818",
      "title": "Quantitative Assessment of Walking (Squawk) With the Canary canturioTM te (CTE) Tibial Extension",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthritis Knee"
      ],
      "interventions": [
        {
          "name": "Clinical Limping Evalution",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Canary Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 88,
      "start_date": "2023-01-31",
      "completion_date": "2024-05-15",
      "has_results": false,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 1,
      "location_summary": "Spartanburg, South Carolina",
      "locations": [
        {
          "city": "Spartanburg",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05693818"
    },
    {
      "nct_id": "NCT02739035",
      "title": "MUA to Treat Postoperative Stiffness After Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Stiffness Following Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Celecoxib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 130,
      "start_date": "2016-04",
      "completion_date": "2022-12",
      "has_results": true,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 16,
      "location_summary": "Little Rock, Arkansas • Denver, Colorado • Chicago, Illinois + 11 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02739035"
    },
    {
      "nct_id": "NCT04910165",
      "title": "Exparel Use in Adductor Canal Block After Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Arthritis Knee",
        "Pain, Postoperative",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Exparel",
          "type": "DRUG"
        },
        {
          "name": "Ropivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Luke's Hospital, Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 100,
      "start_date": "2020-06-01",
      "completion_date": "2021-10-15",
      "has_results": true,
      "last_update_posted_date": "2022-05-20",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 1,
      "location_summary": "Bethlehem, Pennsylvania",
      "locations": [
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04910165"
    },
    {
      "nct_id": "NCT01768871",
      "title": "Evaluation of the VEGA Knee System® Range of Motion",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patients With Total Knee Arthroplasty Using the VEGA System"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Aesculap Implant Systems",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 7,
      "start_date": "2013-01",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2018-11-14",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 3,
      "location_summary": "Denver, Colorado • Vero Beach, Florida • Asheville, North Carolina",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Vero Beach",
          "state": "Florida"
        },
        {
          "city": "Asheville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01768871"
    },
    {
      "nct_id": "NCT00493792",
      "title": "X-3 Polyethylene Survival Outcomes Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee",
        "Total Knee Replacement"
      ],
      "interventions": [
        {
          "name": "X3 Polyethylene",
          "type": "DEVICE"
        },
        {
          "name": "N2Vac Polyethylene",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 518,
      "start_date": "2007-02",
      "completion_date": "2023-11-01",
      "has_results": true,
      "last_update_posted_date": "2024-11-06",
      "last_synced_at": "2026-06-26T11:35:23.824Z",
      "location_count": 3,
      "location_summary": "Phoenix, Arizona • Jacksonville, Florida • Rochester, Minnesota",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00493792"
    }
  ]
}