{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Injury%2C+Trauma",
    "query": {
      "condition": "Knee Injury, Trauma"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 183,
    "total_pages": 19,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Injury%2C+Trauma&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T17:07:48.946Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00426985",
      "title": "Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tendonitis",
        "Bursitis"
      ],
      "interventions": [
        {
          "name": "Ketoprofen Topical Patch 20%",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "APR Applied Pharma Research s.a.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 381,
      "start_date": "2007-02-07",
      "completion_date": "2008-03-10",
      "has_results": false,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00426985"
    },
    {
      "nct_id": "NCT05273463",
      "title": "Comparing Perioperative Education Modalities for ACL Reconstruction on Patient Satisfaction, Self-Efficacy, and Surgical Outcomes",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Injury",
        "Anterior Cruciate Ligament Injuries"
      ],
      "interventions": [
        {
          "name": "Video-Based Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Classroom-Based Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "15 Years to 65 Years"
      },
      "enrollment_count": 105,
      "start_date": "2022-08-23",
      "completion_date": "2027-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05273463"
    },
    {
      "nct_id": "NCT03190889",
      "title": "Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rehabilitation",
        "ACL Reconstruction"
      ],
      "interventions": [
        {
          "name": "HOME",
          "type": "OTHER"
        },
        {
          "name": "TNMT",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "13 Years to 30 Years"
      },
      "enrollment_count": 150,
      "start_date": "2018-08-01",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2026-03-11",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 4,
      "location_summary": "Flowery Branch, Georgia • Minneapolis, Minnesota • Rochester, Minnesota + 1 more",
      "locations": [
        {
          "city": "Flowery Branch",
          "state": "Georgia"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03190889"
    },
    {
      "nct_id": "NCT02010125",
      "title": "Feasibility Trial Using Imaging and Biochemical Technologies to Measure Knee Cartilage Composition in Acute ACL Injury",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Injury of Anterior Cruciate Ligament"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "13 Years to 70 Years"
      },
      "enrollment_count": 89,
      "start_date": "2013-11",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-11-13",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02010125"
    },
    {
      "nct_id": "NCT03372889",
      "title": "On-Q Catheter Caregiver Education",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury",
        "Pain; Catheter (Other)",
        "Satisfaction, Personal"
      ],
      "interventions": [
        {
          "name": "Patient educaiton materials - Print based",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient educaiton materials - Media based",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 178,
      "start_date": "2017-07-11",
      "completion_date": "2020-11-05",
      "has_results": false,
      "last_update_posted_date": "2021-05-04",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03372889"
    },
    {
      "nct_id": "NCT05425810",
      "title": "R21: An Easy-to-use, iNtelligent, Affordable LinEr (ENABLE) System for Socket Fit Assessment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Below Knee (Injury)"
      ],
      "interventions": [
        {
          "name": "Apply ENABLE sensing pad",
          "type": "DEVICE"
        },
        {
          "name": "Insert small pads at pressure tolerant locations",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "North Carolina State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 3,
      "start_date": "2021-04-20",
      "completion_date": "2026-02-27",
      "has_results": false,
      "last_update_posted_date": "2025-05-20",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 1,
      "location_summary": "Raleigh, North Carolina",
      "locations": [
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05425810"
    },
    {
      "nct_id": "NCT03673371",
      "title": "Women's-Specific Footwear With Prosthetic Feet",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lower Limb Amputation Below Knee (Injury)",
        "Lower Limb Amputation Above Knee (Injury)"
      ],
      "interventions": [
        {
          "name": "Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Minneapolis Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2019-03-04",
      "completion_date": "2023-01-06",
      "has_results": false,
      "last_update_posted_date": "2023-03-22",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03673371"
    },
    {
      "nct_id": "NCT04118023",
      "title": "7T MRI to Evaluate Cartilage Defects in the Knee",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cartilage Injury",
        "Knee Injuries",
        "Arthropathy of Knee",
        "Cartilage Damage",
        "Knee Pain Swelling"
      ],
      "interventions": [
        {
          "name": "7 Tesla Magnetic Resonance Imaging Test",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "The Methodist Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 112,
      "start_date": "2019-10-07",
      "completion_date": "2022-09-07",
      "has_results": false,
      "last_update_posted_date": "2025-02-07",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04118023"
    },
    {
      "nct_id": "NCT07135687",
      "title": "Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) Reconstruction",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "ACL Injury",
        "ACL Reconstruction",
        "Scar Formation"
      ],
      "interventions": [
        {
          "name": "Losartan",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2026-08",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-15",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07135687"
    },
    {
      "nct_id": "NCT04875052",
      "title": "Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee",
        "Anterior Cruciate Ligament Injuries",
        "Post-traumatic Osteoarthritis",
        "Quadriceps Muscle Atrophy"
      ],
      "interventions": [
        {
          "name": "Experimental: Whole Body Vibration",
          "type": "DEVICE"
        },
        {
          "name": "Experimental: Local Muscle Vibration",
          "type": "DEVICE"
        },
        {
          "name": "Standard ACL Rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "16 Years to 35 Years"
      },
      "enrollment_count": 114,
      "start_date": "2021-01-11",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-05-31",
      "last_synced_at": "2026-09-25T17:07:48.946Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04875052"
    }
  ]
}