{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Ligament+Injury&page=2",
    "query": {
      "condition": "Knee Ligament Injury",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Ligament+Injury&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T07:50:33.790Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03497780",
      "title": "Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ACL - Anterior Cruciate Ligament Rupture",
        "ACL Injury",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Anterior cruciate ligament reconstruction",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 13,
      "start_date": "2018-11-08",
      "completion_date": "2021-03-25",
      "has_results": false,
      "last_update_posted_date": "2023-04-05",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03497780"
    },
    {
      "nct_id": "NCT03876743",
      "title": "Opiates Prescribing for Knee Arthroscopies and ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries",
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "Group 1-Knee Arthroscopy",
          "type": "OTHER"
        },
        {
          "name": "Group 2-Knee Arthroscopy",
          "type": "OTHER"
        },
        {
          "name": "Group 1-ACL reconstruction",
          "type": "OTHER"
        },
        {
          "name": "Group 2-ACL reconstruction",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 201,
      "start_date": "2018-03-26",
      "completion_date": "2020-07-08",
      "has_results": true,
      "last_update_posted_date": "2020-10-14",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03876743"
    },
    {
      "nct_id": "NCT00332254",
      "title": "Study to Prevent Cartilage Damage Following Acute Knee Injury.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Knee Injury"
      ],
      "interventions": [
        {
          "name": "Anakinra",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 10,
      "start_date": "2006-03",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2013-05-30",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00332254"
    },
    {
      "nct_id": "NCT03132987",
      "title": "Characterizing Clinical and Biomechanical Contributions to Function Following ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Tears"
      ],
      "interventions": [
        {
          "name": "Progressive strengthening program",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 39,
      "start_date": "2017-01",
      "completion_date": "2017-07-31",
      "has_results": false,
      "last_update_posted_date": "2017-08-17",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03132987"
    },
    {
      "nct_id": "NCT01406821",
      "title": "Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich Plasma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tendinopathy"
      ],
      "interventions": [
        {
          "name": "Ultrasound-guided platelet-rich-plasma (PRP) injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Ultrasound-guided dry needling",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2009-08",
      "completion_date": "2019-03-15",
      "has_results": false,
      "last_update_posted_date": "2019-03-29",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 2,
      "location_summary": "Stanford, California • New York, New York",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01406821"
    },
    {
      "nct_id": "NCT07171346",
      "title": "Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Reconstruction",
        "ACL Surgery",
        "ACL Injury",
        "Electrotherapy",
        "Muscle Atrophy or Weakness"
      ],
      "interventions": [
        {
          "name": "Zynex NexWave Electrotherapy Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "15 Years to 50 Years"
      },
      "enrollment_count": 25,
      "start_date": "2026-02-10",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07171346"
    },
    {
      "nct_id": "NCT03273673",
      "title": "Reduction of Risk Factors for ACL Re-injuries Using a Novel Biofeedback Approach",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury"
      ],
      "interventions": [
        {
          "name": "Biofeedback Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "14 Years to 21 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-03-20",
      "completion_date": "2020-05-05",
      "has_results": true,
      "last_update_posted_date": "2020-12-04",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 1,
      "location_summary": "Blacksburg, Virginia",
      "locations": [
        {
          "city": "Blacksburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03273673"
    },
    {
      "nct_id": "NCT02095223",
      "title": "Effect of Electromyographic Biofeedback on Quadriceps Neuromuscular Function in Patients With Quadriceps Inhibition",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries"
      ],
      "interventions": [
        {
          "name": "Electromyographic Biofeedback",
          "type": "DEVICE"
        },
        {
          "name": "Traditional Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 4,
      "start_date": "2013-12",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2017-02-01",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 1,
      "location_summary": "Coral Gables, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02095223"
    },
    {
      "nct_id": "NCT04178538",
      "title": "The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Tear",
        "ACL Injury",
        "Arthroscopy",
        "Anterior Cruciate Ligament Tear"
      ],
      "interventions": [
        {
          "name": "ACL reconstruction with bone marrow, demineralized bone marix, and internal brace augmentation",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard ACL reconstruction with all inside technique",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Marshall University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "14 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2019-12-01",
      "completion_date": "2023-11-11",
      "has_results": false,
      "last_update_posted_date": "2022-04-05",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 1,
      "location_summary": "Huntington, West Virginia",
      "locations": [
        {
          "city": "Huntington",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04178538"
    },
    {
      "nct_id": "NCT04958733",
      "title": "Does Bone Grafting at the Time of Bone-Patellar Tendon-Bone ACL Reconstruction Reduce the Incidence of Post-operative Anterior Knee Pain: A Randomized Controlled Clinical Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "Autologous bone grafting",
          "type": "PROCEDURE"
        },
        {
          "name": "Absence of autologous bone grafting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Hartford Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2021-09-03",
      "completion_date": "2024-06",
      "has_results": false,
      "last_update_posted_date": "2022-08-05",
      "last_synced_at": "2026-06-10T07:50:33.790Z",
      "location_count": 3,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04958733"
    }
  ]
}