{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Pain+Swelling",
    "query": {
      "condition": "Knee Pain Swelling"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T14:56:22.736Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02623660",
      "title": "Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis of Knee",
        "Edema",
        "Wounds and Injuries"
      ],
      "interventions": [
        {
          "name": "ODIN1",
          "type": "DEVICE"
        },
        {
          "name": "Standard Care",
          "type": "OTHER"
        },
        {
          "name": "Diagnostic Device Testing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Bioelectric Research Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 40,
      "start_date": "2016-01",
      "completion_date": "2016-10",
      "has_results": false,
      "last_update_posted_date": "2016-01-12",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 2,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02623660"
    },
    {
      "nct_id": "NCT04751942",
      "title": "Reparel Knee Sleeve vs. TED Hose for Post-op Swelling, Pain and Range of Motion After Total Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis Knees Both"
      ],
      "interventions": [
        {
          "name": "Non-compressive Bioactive Garment",
          "type": "DEVICE"
        },
        {
          "name": "thrombo-embolic deterrent",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 23,
      "start_date": "2023-10-20",
      "completion_date": "2025-01-21",
      "has_results": true,
      "last_update_posted_date": "2025-11-04",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 1,
      "location_summary": "Beachwood, Ohio",
      "locations": [
        {
          "city": "Beachwood",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04751942"
    },
    {
      "nct_id": "NCT04234282",
      "title": "Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Knee Arthritis",
        "Knee Pain Chronic",
        "Knee Deformity",
        "Knee Pain Swelling",
        "Muscle Weakness",
        "Muscle Weakness Condition",
        "Power"
      ],
      "interventions": [
        {
          "name": "Manual Physical Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jennifer Moreno Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "45 Years to 74 Years"
      },
      "enrollment_count": 40,
      "start_date": "2020-01",
      "completion_date": "2020-07",
      "has_results": false,
      "last_update_posted_date": "2020-01-21",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 1,
      "location_summary": "Fort Sam Houston, Texas",
      "locations": [
        {
          "city": "Fort Sam Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04234282"
    },
    {
      "nct_id": "NCT05248308",
      "title": "Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Pain Chronic",
        "Knee Swelling Pain",
        "Arterial Occlusion"
      ],
      "interventions": [
        {
          "name": "Embozene Microspheres",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-07-01",
      "completion_date": "2023-09-01",
      "has_results": false,
      "last_update_posted_date": "2023-03-09",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05248308"
    },
    {
      "nct_id": "NCT04472091",
      "title": "Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Knee Pain Chronic",
        "Knee Pain Swelling",
        "Knee Arthritis",
        "Arterial Occlusion"
      ],
      "interventions": [
        {
          "name": "Genicular artery embolization (GAE)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Andrew Picel",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-01-15",
      "completion_date": "2026-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-02-24",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04472091"
    },
    {
      "nct_id": "NCT02596451",
      "title": "To Study Generic Diclofenac Sodium Topical Gel 1% in the Treatment of Osteoarthritis of the Knee (Degenerative Joint Disease Presented as Joint Pain, Stiffness, Swelling and Restricted Motion).",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Diclofenac Sodium gel, 1%",
          "type": "DRUG"
        },
        {
          "name": "Voltaren® Gel",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Glenmark Pharmaceuticals Ltd. India",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Years and older"
      },
      "enrollment_count": 1164,
      "start_date": "2015-08",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2017-06-28",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 44,
      "location_summary": "Mesa, Arizona • Anaheim, California • Canoga Park, California + 32 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Canoga Park",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02596451"
    },
    {
      "nct_id": "NCT04118023",
      "title": "7T MRI to Evaluate Cartilage Defects in the Knee",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cartilage Injury",
        "Knee Injuries",
        "Arthropathy of Knee",
        "Cartilage Damage",
        "Knee Pain Swelling"
      ],
      "interventions": [
        {
          "name": "7 Tesla Magnetic Resonance Imaging Test",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "The Methodist Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 112,
      "start_date": "2019-10-07",
      "completion_date": "2022-09-07",
      "has_results": false,
      "last_update_posted_date": "2025-02-07",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04118023"
    },
    {
      "nct_id": "NCT07494838",
      "title": "IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Knee Discomfort",
        "Knee Pain Chronic",
        "Knee Swelling Pain"
      ],
      "interventions": [
        {
          "name": "Embolization",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lucas R. Cusumano, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2026-06-30",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07494838"
    },
    {
      "nct_id": "NCT05347602",
      "title": "Gold Factor on Knee Joint Health and Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Arthritis",
        "Knee Osteoarthritis",
        "Knee Pain Chronic",
        "Knee Discomfort",
        "Rheumatoid Arthritis",
        "Knee Pain Swelling"
      ],
      "interventions": [
        {
          "name": "Gold Factor (Gold Nanoparticles, AuNPs)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "4Life Research, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "87 Years",
        "sex": "ALL",
        "summary": "18 Years to 87 Years"
      },
      "enrollment_count": 51,
      "start_date": "2020-08-03",
      "completion_date": "2020-12-30",
      "has_results": false,
      "last_update_posted_date": "2022-07-12",
      "last_synced_at": "2026-07-22T14:56:22.736Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05347602"
    }
  ]
}