{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Prosthesis&page=3",
    "query": {
      "condition": "Knee Prosthesis",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 82,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Prosthesis&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Prosthesis&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T01:47:55.277Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07767097",
      "title": "Stiffness and Low Dose Irradiation RCT",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthrofibrosis of Knee"
      ],
      "interventions": [
        {
          "name": "Low-Dose External Beam Irradiation",
          "type": "RADIATION"
        },
        {
          "name": "Hinged Revision Total Knee Arthroplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "PROCEDURE"
      ],
      "sponsor": "Mount Sinai Hospital, Canada",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2026-04-01",
      "completion_date": "2029-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-17",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07767097"
    },
    {
      "nct_id": "NCT01714492",
      "title": "Mechanics Analysis of Patients Having a Sigma Mobile Bearing TKA",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Prosthesis",
        "Knee Replacement Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Sigma Posterior Stabilizing Rotating Platform TKA Beaded Poly",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Tennessee, Knoxville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 8,
      "start_date": "2012-04",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2019-10-10",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 3,
      "location_summary": "Denver, Colorado • Knoxville, Tennessee",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Knoxville",
          "state": "Tennessee"
        },
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01714492"
    },
    {
      "nct_id": "NCT04113785",
      "title": "In Vivo Kinematics for Subjects Implanted With Klassic Total Knee Arthroplasty (TKA)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Total Knee Arthroplasty",
        "Osteo Arthritis Knee",
        "Knee Implant",
        "Knee Injuries"
      ],
      "interventions": [
        {
          "name": "Klassic Knee System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Tennessee, Knoxville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2018-10-01",
      "completion_date": "2019-06-05",
      "has_results": true,
      "last_update_posted_date": "2019-11-15",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04113785"
    },
    {
      "nct_id": "NCT06968143",
      "title": "Investigating Patient Satisfaction With Smart Knee Implants",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty",
        "Knee Replacement",
        "Knee Replacement Arthroplasty",
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Smart Knee Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2025-09-01",
      "completion_date": "2027-10-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-17",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06968143"
    },
    {
      "nct_id": "NCT02912351",
      "title": "A Post-Market Retrospective Study on Revision Total Knee Arthroplasty Using Medacta GMK® Revision Prosthesis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Patient record review, Radiographs, and questionaires.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medacta USA",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 24,
      "start_date": "2017-01",
      "completion_date": "2022-03",
      "has_results": false,
      "last_update_posted_date": "2022-04-01",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 1,
      "location_summary": "Boise, Idaho",
      "locations": [
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02912351"
    },
    {
      "nct_id": "NCT01754363",
      "title": "Survivorship of Attune Primary Total Knee Prosthesis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Noninflammatory Degenerative Joint Disease"
      ],
      "interventions": [
        {
          "name": "Attune Primary Total Knee Replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy International",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "22 Years to 75 Years"
      },
      "enrollment_count": 1542,
      "start_date": "2013-02-01",
      "completion_date": "2030-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-11-03",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 9,
      "location_summary": "Scottsdale, Arizona • Orange, California • DeLand, Florida + 6 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Mooresville",
          "state": "Indiana"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01754363"
    },
    {
      "nct_id": "NCT07791433",
      "title": "Automatic Prosthetic Foot Stiffness Modulation to Improve Balance in the Real World",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Below Knee"
      ],
      "interventions": [
        {
          "name": "Fixed stiffness prosthesis",
          "type": "DEVICE"
        },
        {
          "name": "Automatic stiffness prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Seattle Institute for Biomedical and Clinical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-11",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07791433"
    },
    {
      "nct_id": "NCT01864434",
      "title": "In Vivo Kinematics Comparison of Stryker or Zimmer Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Prosthesis"
      ],
      "interventions": [
        {
          "name": "Stryker posterior cruciat retaining (PCR) total knee arthroplasty (TKA)",
          "type": "DEVICE"
        },
        {
          "name": "Zimmer PCR TKA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Tennessee, Knoxville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 50,
      "start_date": "2013-06",
      "completion_date": "2014-11",
      "has_results": true,
      "last_update_posted_date": "2019-10-10",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 4,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        },
        {
          "city": "Knoxville",
          "state": "Tennessee"
        },
        {
          "city": "Knoxville",
          "state": "Tennessee"
        },
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01864434"
    },
    {
      "nct_id": "NCT07159490",
      "title": "Lower Limb Prostheses for Individuals Who Carry Infants, Toddlers, and Other Loads",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Prosthesis User"
      ],
      "interventions": [
        {
          "name": "Standard-of-care prosthetic foot",
          "type": "DEVICE"
        },
        {
          "name": "Standard-of-care prosthetic foot with heel-stiffening wedge",
          "type": "DEVICE"
        },
        {
          "name": "Standard-of-care prosthetic foot of one category greater stiffness",
          "type": "DEVICE"
        },
        {
          "name": "Dual keel prosthetic foot",
          "type": "DEVICE"
        },
        {
          "name": "Powered ankle-foot",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Puget Sound Health Care System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 13,
      "start_date": "2020-12-03",
      "completion_date": "2025-10-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07159490"
    },
    {
      "nct_id": "NCT02608957",
      "title": "Evaluation of the Latella™ Knee Implant System for Medial Osteoarthritis Pain Reduction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Latella Knee Implant System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cotera, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 1,
      "start_date": "2015-12",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2017-04-04",
      "last_synced_at": "2026-11-15T01:47:55.277Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Chicago, Illinois",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02608957"
    }
  ]
}