{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Surgery&page=2",
    "query": {
      "condition": "Knee Surgery",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Knee+Surgery&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T05:16:14.055Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03274466",
      "title": "Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Wound",
        "Revision Total Knee Arthroplasty",
        "Wounds and Injuries",
        "Joint Disease",
        "Musculoskeletal Disease",
        "Prosthesis-Related Infections",
        "Infection",
        "Postoperative Complications",
        "Pathologic Processes"
      ],
      "interventions": [
        {
          "name": "Closed Incision Negative Pressure Therapy (ciNPT)",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care Dressing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "KCI USA, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 294,
      "start_date": "2017-12-05",
      "completion_date": "2019-12-19",
      "has_results": true,
      "last_update_posted_date": "2024-10-16",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 17,
      "location_summary": "Weston, Florida • Tucker, Georgia • New Orleans, Louisiana + 10 more",
      "locations": [
        {
          "city": "Weston",
          "state": "Florida"
        },
        {
          "city": "Tucker",
          "state": "Georgia"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "Bay Shore",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03274466"
    },
    {
      "nct_id": "NCT01097135",
      "title": "Evaluating the Effectiveness of 2 Surgical Skin Preparation Methods in Reducing Surgical Wound Drainage After Total Hip or Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Drainage"
      ],
      "interventions": [
        {
          "name": "Duraprep Surgical Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 600,
      "start_date": "2010-03",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2013-09-17",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01097135"
    },
    {
      "nct_id": "NCT05433389",
      "title": "App Delivered Brief Mindfulness Intervention for Surgical Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain",
        "Anxiety State",
        "Depressive State"
      ],
      "interventions": [
        {
          "name": "Breath Counting",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Body Scan",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindful Breathing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness of Pain",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindful Savoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 823,
      "start_date": "2022-06-21",
      "completion_date": "2025-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-06-17",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05433389"
    },
    {
      "nct_id": "NCT06946368",
      "title": "Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Intra-articular Posteromedial Surgeon Administered (IPSA) Block of EXPAREL",
          "type": "PROCEDURE"
        },
        {
          "name": "Adductor Canal Block (ACB) and Local Local Infiltration Analgesia of EXPAREL",
          "type": "PROCEDURE"
        },
        {
          "name": "Local Infiltration Analgesia (LIA) of EXPAREL",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 60,
      "start_date": "2025-08-18",
      "completion_date": "2026-12-11",
      "has_results": false,
      "last_update_posted_date": "2025-09-10",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06946368"
    },
    {
      "nct_id": "NCT03484325",
      "title": "Surgical Joint Registry MBJRF",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis, Knee",
        "Osteoarthritis, Hip"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Memorial Bone and Joint Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 990,
      "start_date": "2009-05",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2019-08-15",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03484325"
    },
    {
      "nct_id": "NCT01301950",
      "title": "Comparison of Surgical Time and Efficiency of Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "Custom Patient Instrumentation",
          "type": "OTHER"
        },
        {
          "name": "Conventional Instruments",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2010-05-01",
      "completion_date": "2013-08-01",
      "has_results": true,
      "last_update_posted_date": "2019-04-10",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 3,
      "location_summary": "Mooresville, Indiana • Bartlesville, Oklahoma • Reston, Virginia",
      "locations": [
        {
          "city": "Mooresville",
          "state": "Indiana"
        },
        {
          "city": "Bartlesville",
          "state": "Oklahoma"
        },
        {
          "city": "Reston",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01301950"
    },
    {
      "nct_id": "NCT02039271",
      "title": "Effects of Music Listening on Pain and Patient Satisfaction Within First 48 Hours After Knee Replacment Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adjunctive Music Therapy in Total Knee Replacement"
      ],
      "interventions": [
        {
          "name": "Music therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "50 Years to 70 Years"
      },
      "enrollment_count": 10,
      "start_date": "2014-02",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2016-12-20",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02039271"
    },
    {
      "nct_id": "NCT04341948",
      "title": "Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Pain",
        "Total Knee Replacement",
        "Total Knee Arthroplasty",
        "Partial Knee Replacement"
      ],
      "interventions": [
        {
          "name": "SPRINT Peripheral Nerve Stimulation (PNS) System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "SPR Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2020-08-06",
      "completion_date": "2024-06-27",
      "has_results": true,
      "last_update_posted_date": "2025-08-27",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 10,
      "location_summary": "Little Rock, Arkansas • San Diego, California • Gainesville, Florida + 7 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Newnan",
          "state": "Georgia"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04341948"
    },
    {
      "nct_id": "NCT04849884",
      "title": "To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty",
        "Replacement",
        "Knee"
      ],
      "interventions": [
        {
          "name": "CORI™ KNEE TENSIONER",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 77,
      "start_date": "2022-03-30",
      "completion_date": "2025-06-04",
      "has_results": true,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 4,
      "location_summary": "New York, New York • New Albany, Ohio • Pittsburgh, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New Albany",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Ashland",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04849884"
    },
    {
      "nct_id": "NCT01112878",
      "title": "Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Shoulder Arthroscopy",
        "Knee Arthroscopy"
      ],
      "interventions": [
        {
          "name": "Sugar pill",
          "type": "DRUG"
        },
        {
          "name": "Gabapentin",
          "type": "DRUG"
        },
        {
          "name": "Clonidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-06",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-09-14",
      "last_synced_at": "2026-07-23T05:16:14.055Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01112878"
    }
  ]
}