{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lacrimal+Apparatus+Disease&page=25", "query": { "condition": "Lacrimal Apparatus Disease", "page": 25 }, "page_size": 10 }, "pagination": { "page": 25, "page_size": 10, "total_count": 643, "total_pages": 65, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lacrimal+Apparatus+Disease&page=26&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lacrimal+Apparatus+Disease&page=24&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-16T15:05:50.943Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03925727", "title": "Tavilermide Ophthalmic Solution for the Treatment of Dry Eye", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Keratoconjunctivitis Sicca", "Dry Eye" ], "interventions": [ { "name": "Tavilermide ophthalmic solution", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Mimetogen Pharmaceuticals USA, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 623, "start_date": "2019-03-28", "completion_date": "2020-06-11", "has_results": true, "last_update_posted_date": "2023-04-05", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 22, "location_summary": "Phoenix, Arizona • Los Angeles, California • Newport Beach, California + 19 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Fort Collins", "state": "Colorado" }, { "city": "Littleton", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03925727" }, { "nct_id": "NCT06329791", "title": "A Phase 3 Study to Evaluate AZR-MD-001 in Patients with Abnormal Meibomian Gland Function and Dry Eye Disease (DED)", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "AZR-MD-001", "type": "DRUG" }, { "name": "Vehicle", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Azura Ophthalmics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 500, "start_date": "2024-05-28", "completion_date": "2025-11", "has_results": false, "last_update_posted_date": "2024-09-27", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 16, "location_summary": "Chandler, Arizona • Glendale, California • Newport Beach, California + 13 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Glendale", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Northbrook", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06329791" }, { "nct_id": "NCT05119920", "title": "Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dry Eye Disease", "Kerato Conjunctivitis Sicca" ], "interventions": [ { "name": "Pilocarpine Ophthalmic Topical Cream, Dose 1", "type": "DRUG" }, { "name": "Pilocarpine Ophthalmic Topical Cream, Dose 2", "type": "DRUG" }, { "name": "Pilocarpine Ophthalmic Topical Cream, Dose 3", "type": "DRUG" }, { "name": "Placebo Ophthalmic Topical Cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Glaukos Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 226, "start_date": "2022-01-03", "completion_date": "2022-07-27", "has_results": false, "last_update_posted_date": "2023-07-12", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 19, "location_summary": "Chandler, Arizona • Sun City, Arizona • Glendale, California + 16 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Glendale", "state": "California" }, { "city": "Mission Hills", "state": "California" }, { "city": "Newport Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05119920" }, { "nct_id": "NCT00883649", "title": "Efficacy and Safety Study of Nutritional Supplements for Treatments of Dry Eye", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Keratoconjunctivitis Sicca" ], "interventions": [ { "name": "Hydroeye", "type": "DIETARY_SUPPLEMENT" }, { "name": "Inactive Capsule", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "Virginia Eye Consultants", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "FEMALE", "summary": "40 Years and older · Female only" }, "enrollment_count": 62, "start_date": "2008-09", "completion_date": null, "has_results": false, "last_update_posted_date": "2012-02-20", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 2, "location_summary": "Houston, Texas • Norfolk, Virginia", "locations": [ { "city": "Houston", "state": "Texas" }, { "city": "Norfolk", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00883649" }, { "nct_id": "NCT01931644", "title": "At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "All Diagnosed Health Conditions", "ADD/ADHD", "Alopecia Areata", "Ankylosing Spondylitis", "Asthma", "Atopic Dermatitis Eczema", "Beta Thalassemia", "Bipolar Disorder", "Breast Cancer", "Celiac Disease", "Cervical Cancer", "Chronic Inflammatory Demyelinating Polyneuropathy", "Chronic Kidney Diseases", "Chronic Obstructive Pulmonary Disease", "Colon Cancer", "Colorectal Cancer", "Crohn's Disease", "Cystic Fibrosis", "Depression", "Diabetes Mellitus", "Duchenne Muscular Dystrophy", "Endometriosis", "Epilepsy", "Facioscapulohumeral Muscular Dystrophy", "G6PD Deficiency", "General Anxiety Disorder", "Hepatitis B", "Hereditary Hemorrhagic Telangiectasia", "HIV/AIDS", "Human Papilloma Virus", "Huntington's Disease", "Idiopathic Thrombocytopenic Purpura", "Insomnia", "Kidney Cancer", "Leukemia", "Lung Cancer", "Lupus Nephritis", "Lymphoma", "Melanoma", "Multiple Myeloma", "Multiple Sclerosis", "Myositis", "Myotonic Dystrophy", "Ovarian Cancer", "Pancreatic Cancer", "Parkinson's Disease", "Polycystic Kidney Diseases", "Prostate Cancer", "Psoriasis", "Psoriatic Arthritis", "Rosacea", "Scleroderma", "Sickle Cell Anemia", "Sickle Cell Trait", "Sjogren's Syndrome", "Skin Cancer", "Spinal Muscular Atrophy", "Systemic Lupus Erythematosus", "Thrombotic Thrombocytopenic Purpura", "Trisomy 21", "Ulcerative Colitis" ], "interventions": [], "intervention_types": [], "sponsor": "Sanguine Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 17667, "start_date": "2013-07", "completion_date": "2024-04", "has_results": false, "last_update_posted_date": "2024-04-18", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01931644" }, { "nct_id": "NCT05493111", "title": "A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "0.003% AR-15512 ophthalmic solution", "type": "DRUG" }, { "name": "AR-15512 vehicle ophthalmic solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aerie Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 275, "start_date": "2022-11-01", "completion_date": "2024-02-28", "has_results": true, "last_update_posted_date": "2025-08-13", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 10, "location_summary": "Chandler, Arizona • Sun City, Arizona • Glendale, California + 7 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Glendale", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Newport Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05493111" }, { "nct_id": "NCT07745062", "title": "The Effectiveness of Systane PRO Preservative Free Verses Blink Triple Care Preservative Free", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Dry Eye Disease (DED)" ], "interventions": [ { "name": "Systane PRO", "type": "DRUG" }, { "name": "Blink tears", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gordon Schanzlin New Vision", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2026-07-17", "completion_date": "2027-04-01", "has_results": false, "last_update_posted_date": "2026-08-04", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07745062" }, { "nct_id": "NCT00388791", "title": "Comparison of Systane Free vs. Saline in the Treatment of Dry Eye", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Dry Eye" ], "interventions": [ { "name": "Systane Free", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Southern California College of Optometry at Marshall B. Ketchum University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 30, "start_date": "2006-10", "completion_date": "2007-04", "has_results": false, "last_update_posted_date": "2016-01-28", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 1, "location_summary": "Fullerton, California", "locations": [ { "city": "Fullerton", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00388791" }, { "nct_id": "NCT01014780", "title": "Tear Film Thickness Measured Using a Novel Technique", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Dry Eye" ], "interventions": [], "intervention_types": [], "sponsor": "Southern California College of Optometry at Marshall B. Ketchum University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2009-11", "completion_date": "2010-10", "has_results": false, "last_update_posted_date": "2010-10-11", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 1, "location_summary": "Fullerton, California", "locations": [ { "city": "Fullerton", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01014780" }, { "nct_id": "NCT00395759", "title": "The Visual Effect of an Investigational Artificial Tear in the Tear Layer.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "Optiva artificial tear by Allergan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Southern California College of Optometry at Marshall B. Ketchum University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 30, "start_date": "2005-09", "completion_date": "2007-09", "has_results": false, "last_update_posted_date": "2007-10-23", "last_synced_at": "2026-10-16T15:05:50.943Z", "location_count": 1, "location_summary": "Fullerton, California", "locations": [ { "city": "Fullerton", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00395759" } ] }