{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lactic+Acidosis&page=2",
    "query": {
      "condition": "Lactic Acidosis",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lactic+Acidosis&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T17:50:37.026Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00015015",
      "title": "Dichloroacetate Kinetics, Metabolism and Toxicology",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lactic Acidosis"
      ],
      "interventions": [
        {
          "name": "Dichloroacetate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Environmental Health Sciences (NIEHS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "3 Months to 65 Years"
      },
      "enrollment_count": 100,
      "start_date": "1994-12",
      "completion_date": "2002-10",
      "has_results": false,
      "last_update_posted_date": "2006-09-04",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00015015"
    },
    {
      "nct_id": "NCT03122678",
      "title": "Thiamine Supplementation in Patients With Septic Shock",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Septic Shock",
        "Shock, Septic",
        "Lactic Acidosis",
        "Thiamine Deficiency"
      ],
      "interventions": [
        {
          "name": "Thiamine",
          "type": "DRUG"
        },
        {
          "name": "Placebos",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2016-11-05",
      "completion_date": "2019-03-14",
      "has_results": false,
      "last_update_posted_date": "2019-03-15",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "Weston, Florida",
      "locations": [
        {
          "city": "Weston",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03122678"
    },
    {
      "nct_id": "NCT00638040",
      "title": "The Gene Expression Studies of the Role of Tumor Microenvironments in Tumor Progression",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxia",
        "Lactic Acidosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2009-09",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2014-07-11",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00638040"
    },
    {
      "nct_id": "NCT01797276",
      "title": "Dichloroacetate Treatment of Congenital Lactic Acidosis Phase B: Expanded Access",
      "overall_status": "NO_LONGER_AVAILABLE",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Mitochondrial Enzyme Deficiencies"
      ],
      "interventions": [
        {
          "name": "Dichloroacetate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-08-08",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01797276"
    },
    {
      "nct_id": "NCT00887562",
      "title": "Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "MELAS Syndrome"
      ],
      "interventions": [
        {
          "name": "Idebenone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Michio Hirano",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "8 Years to 65 Years"
      },
      "enrollment_count": 27,
      "start_date": "2009-05",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2016-10-26",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00887562"
    },
    {
      "nct_id": "NCT00004493",
      "title": "Phase II Pilot Randomized Study of Sodium Dichloroacetate in Patients With Congenital Lactic Acidemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lactic Acidosis"
      ],
      "interventions": [
        {
          "name": "sodium dichloroacetate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "3 Months and older"
      },
      "enrollment_count": 75,
      "start_date": "1998-09",
      "completion_date": "2003-09",
      "has_results": false,
      "last_update_posted_date": "2015-03-25",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00004493"
    },
    {
      "nct_id": "NCT01833247",
      "title": "Lactic Acidosis During and After Seizures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Epilepsy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 12,
      "start_date": "2012-07",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2017-05-05",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01833247"
    },
    {
      "nct_id": "NCT03025659",
      "title": "Lactate Acidosis in Postoperative Hearts",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-cardiac Surgery",
        "Hyperlactatemia"
      ],
      "interventions": [
        {
          "name": "Pyruvate levels",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 43,
      "start_date": "2017-05-28",
      "completion_date": "2019-01-24",
      "has_results": false,
      "last_update_posted_date": "2020-03-23",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03025659"
    },
    {
      "nct_id": "NCT00739089",
      "title": "Presep and Vascath Interaction Study",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hemodynamics",
        "Renal Dialysis",
        "Sepsis",
        "Shock"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2008-08",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2017-11-08",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00739089"
    },
    {
      "nct_id": "NCT02482597",
      "title": "Whole Body Periodic Acceleration on Blood Lactate and Recovery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acidosis, Lactic"
      ],
      "interventions": [
        {
          "name": "Whole Body Periodic Acceleration",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 32,
      "start_date": "2015-06",
      "completion_date": "2017-06-01",
      "has_results": false,
      "last_update_posted_date": "2018-03-29",
      "last_synced_at": "2026-06-10T17:50:37.026Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02482597"
    }
  ]
}