{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lateral+Canthal+Lines+%28LCL%29",
    "query": {
      "condition": "Lateral Canthal Lines (LCL)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T18:14:04.281Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04985916",
      "title": "ET-01 in Subjects With Lateral Canthal Lines, LCL-210",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lateral Canthal Lines, LCL",
        "Crow's Feet"
      ],
      "interventions": [
        {
          "name": "Vehicle",
          "type": "BIOLOGICAL"
        },
        {
          "name": "botulinum toxin, Type A",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Eirion Therapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "25 Years to 65 Years"
      },
      "enrollment_count": 280,
      "start_date": "2021-07-19",
      "completion_date": "2024-02-08",
      "has_results": false,
      "last_update_posted_date": "2024-12-09",
      "last_synced_at": "2026-07-23T18:14:04.281Z",
      "location_count": 19,
      "location_summary": "Scottsdale, Arizona • San Diego, California • Aventura, Florida + 16 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Aventura",
          "state": "Florida"
        },
        {
          "city": "Boca Raton",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04985916"
    },
    {
      "nct_id": "NCT03911102",
      "title": "Efficacy and Safety of Increasing Doses of DaxibotulinumtoxinA for Injection (DAXI for Injection) in the Treatment of Moderate or Severe Lateral Canthal Lines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lateral Canthal Lines"
      ],
      "interventions": [
        {
          "name": "DaxibotulinumtoxinA for injection",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Revance Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 63,
      "start_date": "2019-03-11",
      "completion_date": "2020-04-23",
      "has_results": true,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-07-23T18:14:04.281Z",
      "location_count": 4,
      "location_summary": "Sacramento, California • Sarasota, Florida • Itasca, Illinois + 1 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Itasca",
          "state": "Illinois"
        },
        {
          "city": "Arlington",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03911102"
    },
    {
      "nct_id": "NCT04259086",
      "title": "Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Upper Facial Lines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Upper Facial Lines (Glabellar Lines, Forehead Lines, & Lateral Canthal Lines)"
      ],
      "interventions": [
        {
          "name": "DaxibotulinumtoxinA for injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Revance Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2019-12-06",
      "completion_date": "2020-11-02",
      "has_results": true,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-07-23T18:14:04.281Z",
      "location_count": 6,
      "location_summary": "Manhattan Beach, California • San Diego, California • Santa Monica, California + 3 more",
      "locations": [
        {
          "city": "Manhattan Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Chestnut Hill",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04259086"
    },
    {
      "nct_id": "NCT03912805",
      "title": "ET-01 in Subjects With Lateral Canthal Lines, LCL-209",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lateral Canthal Lines, LCL",
        "Crow's Feet"
      ],
      "interventions": [
        {
          "name": "botulinum toxin, Type A",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Vehicle",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Eirion Therapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 65 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2019-02-27",
      "completion_date": "2019-10-04",
      "has_results": true,
      "last_update_posted_date": "2022-07-28",
      "last_synced_at": "2026-07-23T18:14:04.281Z",
      "location_count": 3,
      "location_summary": "Pinellas Park, Florida • Yardley, Pennsylvania • Norfolk, Virginia",
      "locations": [
        {
          "city": "Pinellas Park",
          "state": "Florida"
        },
        {
          "city": "Yardley",
          "state": "Pennsylvania"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03912805"
    },
    {
      "nct_id": "NCT04247074",
      "title": "Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Glabellar Frown Lines (GL)",
        "Lateral Canthal Lines (LCL)"
      ],
      "interventions": [
        {
          "name": "botulinum toxin neuromodulator",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 413,
      "start_date": "2020-02-10",
      "completion_date": "2021-02-26",
      "has_results": true,
      "last_update_posted_date": "2023-09-06",
      "last_synced_at": "2026-07-23T18:14:04.281Z",
      "location_count": 11,
      "location_summary": "Encino, California • Santa Monica, California • West Hollywood, California + 8 more",
      "locations": [
        {
          "city": "Encino",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "West Hollywood",
          "state": "California"
        },
        {
          "city": "Aventura",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04247074"
    },
    {
      "nct_id": "NCT04157686",
      "title": "MT10109L in the Long-term, Open-label Treatment of Glabellar Lines (GL) and Lateral Canthal Lines (LCL)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Glabellar Lines",
        "Lateral Canthal Lines"
      ],
      "interventions": [
        {
          "name": "MT10109L Dose 1",
          "type": "DRUG"
        },
        {
          "name": "MT10109L Dose 2",
          "type": "DRUG"
        },
        {
          "name": "MT10109L Dose 1 + Dose 2",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medy-Tox",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 957,
      "start_date": "2019-10-23",
      "completion_date": "2023-02-16",
      "has_results": true,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-07-23T18:14:04.281Z",
      "location_count": 18,
      "location_summary": "Scottsdale, Arizona • Newport Beach, California • Solana Beach, California + 14 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Solana Beach",
          "state": "California"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04157686"
    },
    {
      "nct_id": "NCT03721016",
      "title": "MT10109L in the Treatment of Glabellar Lines (GL) With or Without Concurrent Treatment of Lateral Canthal Lines (LCL)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Glabellar Lines",
        "Lateral Canthal Lines"
      ],
      "interventions": [
        {
          "name": "MT10109L",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medy-Tox",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 415,
      "start_date": "2018-10-26",
      "completion_date": "2021-01-22",
      "has_results": true,
      "last_update_posted_date": "2023-05-25",
      "last_synced_at": "2026-07-23T18:14:04.281Z",
      "location_count": 9,
      "location_summary": "Glendale, Arizona • Newport Beach, California • Coral Gables, Florida + 6 more",
      "locations": [
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Metairie",
          "state": "Louisiana"
        },
        {
          "city": "Hunt Valley",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03721016"
    }
  ]
}