{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Left-Sided+Heart+Failure&page=12",
    "query": {
      "condition": "Left-Sided Heart Failure",
      "page": 12
    },
    "page_size": 10
  },
  "pagination": {
    "page": 12,
    "page_size": 10,
    "total_count": 290,
    "total_pages": 29,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Left-Sided+Heart+Failure&page=13&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Left-Sided+Heart+Failure&page=11&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T23:16:35.145Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04154878",
      "title": "2 New Measurements Used to Describe the Filling Phase of the Left Ventricle (LV).",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diastolic Heart Failure",
        "Left Ventricular Diastolic Dysfunction",
        "Left Ventricular Diastolic Collapse"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "AdventHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "45 Years to 85 Years"
      },
      "enrollment_count": 111,
      "start_date": "2019-10-30",
      "completion_date": "2023-06-21",
      "has_results": false,
      "last_update_posted_date": "2023-06-29",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04154878"
    },
    {
      "nct_id": "NCT03580759",
      "title": "Exergaming in Advanced HF With Multiple Chronic Conditions Prior to LVAD Implantation or Heart Transplant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart-Assist Devices",
        "Heart Failure NYHA Class IV",
        "Exercise Training"
      ],
      "interventions": [
        {
          "name": "PREHAB",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2019-03-01",
      "completion_date": "2021-03-01",
      "has_results": false,
      "last_update_posted_date": "2023-09-29",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03580759"
    },
    {
      "nct_id": "NCT02290028",
      "title": "Sentus QP - Extended CRT Evaluation With Quadripolar Left Ventricular Leads",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Sentus QP left ventricular lead",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biotronik SE & Co. KG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2226,
      "start_date": "2014-12-16",
      "completion_date": "2020-01-23",
      "has_results": true,
      "last_update_posted_date": "2021-03-24",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 75,
      "location_summary": "Fairhope, Alabama • Anchorage, Alaska • Chula Vista, California + 64 more",
      "locations": [
        {
          "city": "Fairhope",
          "state": "Alabama"
        },
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Inglewood",
          "state": "California"
        },
        {
          "city": "Rancho Mirage",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02290028"
    },
    {
      "nct_id": "NCT00585546",
      "title": "Harefield Recovery Protocol Study for Patients With Refractory Chronic Heart Failure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Heart Failure",
        "Dilated Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "clenbuterol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Francis D. Pagani",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2007-07",
      "completion_date": "2010-03",
      "has_results": true,
      "last_update_posted_date": "2017-12-15",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 7,
      "location_summary": "Washington D.C., District of Columbia • Chicago, Illinois • Ann Arbor, Michigan + 4 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00585546"
    },
    {
      "nct_id": "NCT03247829",
      "title": "Investigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Hemodynamic management using CardioMEMS HF System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 101,
      "start_date": "2017-08-24",
      "completion_date": "2020-06-30",
      "has_results": true,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 23,
      "location_summary": "La Jolla, California • Los Angeles, California • San Diego, California + 18 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03247829"
    },
    {
      "nct_id": "NCT05327062",
      "title": "Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Resynchronization Therapy",
        "Chronic Heart Failure",
        "Left Bundle-Branch Block"
      ],
      "interventions": [
        {
          "name": "CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "XSpline S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2023-03-06",
      "completion_date": "2025-09",
      "has_results": false,
      "last_update_posted_date": "2024-10-24",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 4,
      "location_summary": "Chicago, Illinois • Boston, Massachusetts • Durham, North Carolina",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05327062"
    },
    {
      "nct_id": "NCT01431027",
      "title": "Left Ventricular Torsional Hysteresis: A Global Parameter for Diastolic Function",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure",
        "Diastolic Heart Failure",
        "Heart Failure With Normal Ejection Fraction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2011-08",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-08-18",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01431027"
    },
    {
      "nct_id": "NCT06763549",
      "title": "COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiopulmonary Failure",
        "Myocardial Infarction (MI)",
        "Heart Decompensation",
        "Heart Failure",
        "HFrEF - Heart Failure with Reduced Ejection Fraction",
        "HFpEF - Heart Failure with Preserved Ejection Fraction",
        "Syncopation",
        "Syncope",
        "Ischemic Cardiovascular Disease",
        "STEMI",
        "STEMI (ST Elevation MI)",
        "Atrial Fibrillation (AF)",
        "Atrial Enlargement",
        "LVF",
        "Conduction Defect",
        "Conduction Abnormalities",
        "Heart Block",
        "Valvular Diseases",
        "Cardiac Output, Low",
        "Stroke Volume",
        "Stroke Volume Variation",
        "Hyperkalemia",
        "Hypercalcemia",
        "Hypocalcemia",
        "LV Dysfunction",
        "QT Prolongation",
        "Sudden Cardiac Death Due to Cardiac Arrhythmia",
        "Ventricular Arrhythmia",
        "Pacing",
        "Pacing Induced Dyssynchrony",
        "Silent Ischemia",
        "Pericarditis",
        "Sleep Related Breathing Disorder",
        "RSA",
        "Apnea, Obstructive",
        "Cardiac Output Measurement",
        "Respiratory Impedance",
        "CRT And/or ICD",
        "Infarction",
        "Cardiomyopathies, Primary",
        "Hypertrophy"
      ],
      "interventions": [
        {
          "name": "SUBPROTOCOL A",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL B",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL C",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL D",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL E",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL F",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL G",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL H",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Peerbridge Health, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15000,
      "start_date": "2024-11-16",
      "completion_date": "2026-04-15",
      "has_results": false,
      "last_update_posted_date": "2025-01-08",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 1,
      "location_summary": "Melbourne, Florida",
      "locations": [
        {
          "city": "Melbourne",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06763549"
    },
    {
      "nct_id": "NCT05884411",
      "title": "Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Response",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Systolic Heart Failure",
        "Heart Failure With Reduced Ejection Fraction",
        "CRT Non-Response",
        "Left Bundle Branch Area Pacing"
      ],
      "interventions": [
        {
          "name": "Left bundle branch area pacing",
          "type": "DEVICE"
        },
        {
          "name": "Cardiac MRI",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2023-04-30",
      "completion_date": "2025-08-05",
      "has_results": false,
      "last_update_posted_date": "2025-08-11",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05884411"
    },
    {
      "nct_id": "NCT01440517",
      "title": "Results of Tc99m-Maraciclatide Scintigraphy in Subjects With Diabetes Mellitus and Heart Failure With Preserved Left Ventricular Ejection Fraction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes Mellitus",
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Tc99m-Maraciclatide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GE Healthcare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 4,
      "start_date": "2011-08",
      "completion_date": "2012-03",
      "has_results": true,
      "last_update_posted_date": "2014-02-04",
      "last_synced_at": "2026-10-22T23:16:35.145Z",
      "location_count": 1,
      "location_summary": "Princeton, New Jersey",
      "locations": [
        {
          "city": "Princeton",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01440517"
    }
  ]
}