{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Leg+Injuries+and+Disorders&page=2",
    "query": {
      "condition": "Leg Injuries and Disorders",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Leg+Injuries+and+Disorders&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-27T00:36:00.358Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07006675",
      "title": "Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tibial Fractures",
        "Pain"
      ],
      "interventions": [
        {
          "name": "600 mg Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Major Extremity Trauma Research Consortium",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2021-05-26",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2025-06-05",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 13,
      "location_summary": "Indianapolis, Indiana • Baltimore, Maryland • Cambridge, Massachusetts + 9 more",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07006675"
    },
    {
      "nct_id": "NCT03753373",
      "title": "Acupuncture for Medial Tibial Stress Syndrome in the Primary Care Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Medial Tibial Stress Syndrome"
      ],
      "interventions": [
        {
          "name": "Acupuncture",
          "type": "OTHER"
        },
        {
          "name": "Home Exercise Program",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Eglin AFB Regional Hospital",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 81,
      "start_date": "2019-01-11",
      "completion_date": "2021-11-23",
      "has_results": false,
      "last_update_posted_date": "2021-11-30",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 1,
      "location_summary": "Eglin Air Force Base, Florida",
      "locations": [
        {
          "city": "Eglin Air Force Base",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03753373"
    },
    {
      "nct_id": "NCT05007366",
      "title": "Optimizing Gait Biomechanics for Posttraumatic Osteoarthritis Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injuries",
        "Post-traumatic Osteoarthritis",
        "Knee Osteoarthritis",
        "Knee Injuries",
        "Cartilage, Articular",
        "Gait"
      ],
      "interventions": [
        {
          "name": "Real-time gait biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham real-time gait biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 24,
      "start_date": "2021-08-05",
      "completion_date": "2022-12-02",
      "has_results": false,
      "last_update_posted_date": "2023-04-18",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05007366"
    },
    {
      "nct_id": "NCT02119754",
      "title": "Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Infection"
      ],
      "interventions": [
        {
          "name": "Plurogel PN",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "PluroGen Therapeutics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2013-10",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2014-09-25",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 15,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Oakland, California + 8 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Hamden",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02119754"
    },
    {
      "nct_id": "NCT03338842",
      "title": "Virtual Reality Treatment for Phantom Limb Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Above Knee (Injury)",
        "Lower Limb Amputation Below Knee (Injury)",
        "Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Distractor and Lower limb VR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2018-01-12",
      "completion_date": "2019-11-01",
      "has_results": false,
      "last_update_posted_date": "2020-06-16",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03338842"
    },
    {
      "nct_id": "NCT02467998",
      "title": "Negative Pressure Wound Therapy Registry",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcers",
        "Venous Stasis Ulcer",
        "Pressure Ulcer",
        "Surgical Wound Dehiscence",
        "Burns",
        "Other Types of Chronic Non Healing Wounds"
      ],
      "interventions": [
        {
          "name": "NPWT",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "U.S. Wound Registry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 50000,
      "start_date": "2005-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2018-05-01",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 1,
      "location_summary": "The Woodlands, Texas",
      "locations": [
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02467998"
    },
    {
      "nct_id": "NCT06998134",
      "title": "Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Muscle Weakness",
        "Problems Moving Their Arms and Legs"
      ],
      "interventions": [
        {
          "name": "Extension assist knee ankle foot orthosis (EA-KAFO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "5 Years to 25 Years"
      },
      "enrollment_count": 23,
      "start_date": "2026-07-01",
      "completion_date": "2028-08-18",
      "has_results": false,
      "last_update_posted_date": "2026-06-26",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06998134"
    },
    {
      "nct_id": "NCT00578604",
      "title": "Non-Invasive Assessment of Wound Healing With Optical Methods",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "diffuse near infrared spectroscopy measurements",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Drexel University College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 38,
      "start_date": "2007-09",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2017-03-30",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00578604"
    },
    {
      "nct_id": "NCT02274116",
      "title": "Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "SHAM - Intermittent Room Air - room air mixture",
          "type": "OTHER"
        },
        {
          "name": "AIH - Intermittent Hypoxia - hypoxia air mixture",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2014-10",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02274116"
    },
    {
      "nct_id": "NCT06629506",
      "title": "MicroMatrix® Flex in Tunneling Wounds",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pressure Injury",
        "Venous Ulcer",
        "Necrotizing Soft Tissue Infection",
        "Diabetic Ulcers",
        "Draining Wound"
      ],
      "interventions": [
        {
          "name": "MicroMatrix® Flex",
          "type": "DEVICE"
        },
        {
          "name": "MicroMatrix® UBM Particulate",
          "type": "DEVICE"
        },
        {
          "name": "Cytal® Wound Matrix 2-Layer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2024-12-12",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-06-27T00:36:00.358Z",
      "location_count": 3,
      "location_summary": "Aurora, Colorado • Washington D.C., District of Columbia • Lake Success, New York",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Lake Success",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06629506"
    }
  ]
}