{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Limb+Amputation&page=2",
    "query": {
      "condition": "Limb Amputation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Limb+Amputation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T16:28:07.378Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07011420",
      "title": "Effects of Myoelectric Channel Count and Targeting for Upper Limb Prosthetic Control",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Amputation, Traumatic",
        "Amputation, Congenital",
        "Prosthesis User",
        "Upper Limb Amputation Below Elbow (Injury)",
        "Amputation; Traumatic, Arm: Forearm, Between Elbow and Wrist"
      ],
      "interventions": [
        {
          "name": "Experimental socket with 4 untargeted channels active",
          "type": "DEVICE"
        },
        {
          "name": "Experimental socket with 8 untargeted channels active",
          "type": "DEVICE"
        },
        {
          "name": "Experimental socket with up to 16 untargeted channels active",
          "type": "DEVICE"
        },
        {
          "name": "Experimental socket with 8 targeted channels active",
          "type": "DEVICE"
        },
        {
          "name": "Coapt EMG Cuff",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Liberating Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2025-10",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2025-09-03",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Holliston, Massachusetts",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Holliston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07011420"
    },
    {
      "nct_id": "NCT03882073",
      "title": "A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Modified amputation procedure",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard amputation procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2019-05-01",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 4,
      "location_summary": "Bethesda, Maryland • Boston, Massachusetts • Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03882073"
    },
    {
      "nct_id": "NCT05392803",
      "title": "Pulsed Electromagnetic Fields for Post-Amputation Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Phantom Limb Pain",
        "Residual Limb Pain"
      ],
      "interventions": [
        {
          "name": "Active then Sham Treatment",
          "type": "DEVICE"
        },
        {
          "name": "Sham then Active Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2022-08-05",
      "completion_date": "2023-08-17",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05392803"
    },
    {
      "nct_id": "NCT05009394",
      "title": "Surgical Treatments for Postamputation Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Residual Limb Pain",
        "Amputation Neuroma",
        "Phantom Limb Pain",
        "Pain, Neuropathic",
        "Pain, Nerve"
      ],
      "interventions": [
        {
          "name": "Targeted Muscle Reinnervation (TMR)",
          "type": "PROCEDURE"
        },
        {
          "name": "Regenerative Peripheral Nerve Interface (RPNI)",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard neuroma treatment, neuroma excision, and muscle burying",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Prometei Pain Rehabilitation Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2023-06-20",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2025-01-09",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • Boston, Massachusetts • Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05009394"
    },
    {
      "nct_id": "NCT03670004",
      "title": "Falls in Older Persons With Limb Loss",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amputation",
        "Elderly"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 23,
      "start_date": "2017-02-02",
      "completion_date": "2020-10-31",
      "has_results": true,
      "last_update_posted_date": "2022-11-07",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03670004"
    },
    {
      "nct_id": "NCT04658368",
      "title": "Patient Reported Outcomes Following Targeted Muscle Reinnervation",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Primary TMR",
          "type": "PROCEDURE"
        },
        {
          "name": "Secondary TMR",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2020-12-29",
      "completion_date": "2022-09-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-05",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04658368"
    },
    {
      "nct_id": "NCT07044323",
      "title": "Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Phantom Pain Following Amputation of Lower Limb",
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Active Virtual Reality Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Albert Einstein Healthcare Network",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 44,
      "start_date": "2025-06-16",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-08",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 3,
      "location_summary": "Philadelphia, Pennsylvania • Seattle, Washington",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07044323"
    },
    {
      "nct_id": "NCT07486063",
      "title": "Motorized Prostheses for Lower-limb Amputees",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Lower-Limb Amputation"
      ],
      "interventions": [
        {
          "name": "Powered and passive lower limb prosthesis and control",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-07-01",
      "completion_date": "2032-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07486063"
    },
    {
      "nct_id": "NCT01293214",
      "title": "Vascularized Composite Allotransplantation for Multiple Extremity Amputations",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Limb Amputation",
        "Extremity Amputation"
      ],
      "interventions": [
        {
          "name": "Limb transplantation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2010-02-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-02-05",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01293214"
    },
    {
      "nct_id": "NCT05929508",
      "title": "Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Amputation of Lower Extremity"
      ],
      "interventions": [
        {
          "name": "Ischemic Preconditioning",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-04-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-17",
      "last_synced_at": "2026-07-22T16:28:07.378Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05929508"
    }
  ]
}