{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Local+Anesthetics&page=2",
    "query": {
      "condition": "Local Anesthetics",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Local+Anesthetics&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T14:50:06.096Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00756600",
      "title": "A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Inguinal Hernia"
      ],
      "interventions": [
        {
          "name": "Regional Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "General Anesthesia",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "60 Weeks",
        "sex": "ALL",
        "summary": "Up to 60 Weeks"
      },
      "enrollment_count": 643,
      "start_date": "2006-10-23",
      "completion_date": "2018-06-30",
      "has_results": true,
      "last_update_posted_date": "2020-04-29",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 10,
      "location_summary": "Aurora, Colorado • Chicago, Illinois • Iowa City, Iowa + 7 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00756600"
    },
    {
      "nct_id": "NCT03390426",
      "title": "Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tourniquet Hypertension",
        "Intraoperative Hypertension",
        "Total Ankle Arthroplasty",
        "Ankle Fusion"
      ],
      "interventions": [
        {
          "name": "Mepivacaine",
          "type": "DRUG"
        },
        {
          "name": "Perifemoral Injection of Local Anesthetic",
          "type": "PROCEDURE"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 31,
      "start_date": "2018-05-03",
      "completion_date": "2018-10-28",
      "has_results": true,
      "last_update_posted_date": "2021-05-05",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03390426"
    },
    {
      "nct_id": "NCT05476679",
      "title": "Evaluation the Effects of Various Treatments on RZL-012-Induced Adverse Events",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Submental Fat"
      ],
      "interventions": [
        {
          "name": "RZL-012",
          "type": "DRUG"
        },
        {
          "name": "RZL-012+Lidacaine injection prior treatment",
          "type": "DRUG"
        },
        {
          "name": "RZL-012+Medrol",
          "type": "DRUG"
        },
        {
          "name": "RZL-012+Celecoxib+Zyrtec",
          "type": "DRUG"
        },
        {
          "name": "RZL-012+facial and neck wrap",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Raziel Therapeutics Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 48,
      "start_date": "2022-09-25",
      "completion_date": "2023-06-12",
      "has_results": true,
      "last_update_posted_date": "2024-01-30",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 1,
      "location_summary": "Manhattan, New York",
      "locations": [
        {
          "city": "Manhattan",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05476679"
    },
    {
      "nct_id": "NCT01701102",
      "title": "Study to Find Optimal Dose of Local Spinal Anesthetic (Mepivacaine) Combined With Narcotic (Fentanyl) For Knee Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroscopic Knee Surgery"
      ],
      "interventions": [
        {
          "name": "Mepivacaine (24 mg) plus fentanyl",
          "type": "PROCEDURE"
        },
        {
          "name": "Mepivacaine (27 mg) plus fentanyl",
          "type": "PROCEDURE"
        },
        {
          "name": "Mepivacaine (30 mg) plus fentanyl",
          "type": "PROCEDURE"
        },
        {
          "name": "Mepivacaine",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 56,
      "start_date": "2011-12",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2016-04-05",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01701102"
    },
    {
      "nct_id": "NCT01662401",
      "title": "Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 66,
      "start_date": "2008-05",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2013-07-02",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01662401"
    },
    {
      "nct_id": "NCT02297191",
      "title": "Ultrasound Guided Local Anesthetic Block: Thoracolumbar Interfascial Plane",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Thoracolumbar Interfascial Plane Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Ropivicaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2014-07",
      "completion_date": "2014-11",
      "has_results": false,
      "last_update_posted_date": "2018-06-20",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02297191"
    },
    {
      "nct_id": "NCT00930046",
      "title": "The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstruction of Pelviureteric Junction"
      ],
      "interventions": [
        {
          "name": "Ropivacaine wound catheter",
          "type": "DEVICE"
        },
        {
          "name": "Saline wound catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "3 Months to 14 Years"
      },
      "enrollment_count": 15,
      "start_date": "2009-04-24",
      "completion_date": "2011-09-06",
      "has_results": true,
      "last_update_posted_date": "2020-04-28",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00930046"
    },
    {
      "nct_id": "NCT06982027",
      "title": "Peripheral Regional Blockade and EMG",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgery"
      ],
      "interventions": [
        {
          "name": "BlockSynop surface electromyography device",
          "type": "DEVICE"
        },
        {
          "name": "Peripheral nerve block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "0 Years to 21 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-09-03",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-30",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06982027"
    },
    {
      "nct_id": "NCT06806410",
      "title": "The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hand Surgery",
        "Wrist Surgery",
        "Elbow Surgery",
        "Fracture Fixation",
        "Dupuytren Contracture",
        "Finger Fracture",
        "Wrist Arthropathy",
        "Distal Radius Fracture"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine (LB)",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Luke's Hospital, Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2023-05-01",
      "completion_date": "2025-01-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-06",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 1,
      "location_summary": "Bethlehem, Pennsylvania",
      "locations": [
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06806410"
    },
    {
      "nct_id": "NCT02904993",
      "title": "Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Joint Disease"
      ],
      "interventions": [
        {
          "name": "L2 paravertebral block",
          "type": "OTHER"
        },
        {
          "name": "periarticular injection group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 9,
      "start_date": "2016-05",
      "completion_date": "2016-10",
      "has_results": false,
      "last_update_posted_date": "2016-11-16",
      "last_synced_at": "2026-06-26T14:50:06.096Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02904993"
    }
  ]
}