{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Injury",
    "query": {
      "condition": "Lower Extremity Injury"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 345,
    "total_pages": 35,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Injury&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T05:39:08.337Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00855023",
      "title": "Knee Alignment Contributions to Anterior Cruciate Ligament (ACL) Injury",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Injuries"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The Orthopaedic Center, Maryland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 25,
      "start_date": "2007-11",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2020-03-18",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 1,
      "location_summary": "Rockville, Maryland",
      "locations": [
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00855023"
    },
    {
      "nct_id": "NCT03876743",
      "title": "Opiates Prescribing for Knee Arthroscopies and ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries",
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "Group 1-Knee Arthroscopy",
          "type": "OTHER"
        },
        {
          "name": "Group 2-Knee Arthroscopy",
          "type": "OTHER"
        },
        {
          "name": "Group 1-ACL reconstruction",
          "type": "OTHER"
        },
        {
          "name": "Group 2-ACL reconstruction",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 201,
      "start_date": "2018-03-26",
      "completion_date": "2020-07-08",
      "has_results": true,
      "last_update_posted_date": "2020-10-14",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03876743"
    },
    {
      "nct_id": "NCT06635668",
      "title": "Baseline ACL Injury Risk Screening and Normative Data",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ACL Injury",
        "Anterior Cruciate Ligament Injuries",
        "Musculoskeletal Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Sanford Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "10 Years to 65 Years"
      },
      "enrollment_count": 5000,
      "start_date": "2022-07-19",
      "completion_date": "2033-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 1,
      "location_summary": "Fargo, North Dakota",
      "locations": [
        {
          "city": "Fargo",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06635668"
    },
    {
      "nct_id": "NCT05442879",
      "title": "Knowledge Translation Intervention for ACL Injury Prevention Program in Youth Soccer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injuries",
        "Lower Extremity Problem"
      ],
      "interventions": [
        {
          "name": "Knowledge Translation Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Educational handout",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "14 Years to 19 Years"
      },
      "enrollment_count": 671,
      "start_date": "2022-07-01",
      "completion_date": "2024-08-30",
      "has_results": false,
      "last_update_posted_date": "2024-10-15",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 1,
      "location_summary": "Flint, Michigan",
      "locations": [
        {
          "city": "Flint",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05442879"
    },
    {
      "nct_id": "NCT04670042",
      "title": "Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Injury; Nerve, Peripheral, Multiple",
        "Chronic Post-Procedural Pain",
        "Total Knee Arthroplasty",
        "Surgery",
        "Knee Injuries",
        "Knee Pain Chronic",
        "Postoperative Pain",
        "Chronic Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-06-25",
      "completion_date": "2024-05",
      "has_results": false,
      "last_update_posted_date": "2022-10-20",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 1,
      "location_summary": "Redwood City, California",
      "locations": [
        {
          "city": "Redwood City",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04670042"
    },
    {
      "nct_id": "NCT05488054",
      "title": "Muscle O2 Saturation and Hemoglobin Levels During Rehabilitation From Arthroscopic Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Injury",
        "Hip Injuries"
      ],
      "interventions": [
        {
          "name": "Physical Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Monitored Work-out",
          "type": "PROCEDURE"
        },
        {
          "name": "Moxy Oxygen Sensor Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "14 Years to 30 Years"
      },
      "enrollment_count": 226,
      "start_date": "2022-08-08",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 2,
      "location_summary": "Avon, Ohio • Cleveland, Ohio",
      "locations": [
        {
          "city": "Avon",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05488054"
    },
    {
      "nct_id": "NCT02383056",
      "title": "Doubleblinded RCT of the Omnilux on Lower Extremity Surgical Wounds Left to Heal by Second Intention",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wound"
      ],
      "interventions": [
        {
          "name": "Omnilux",
          "type": "DEVICE"
        },
        {
          "name": "Omnilux Sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 14,
      "start_date": "2012-12",
      "completion_date": "2017-11",
      "has_results": true,
      "last_update_posted_date": "2019-05-23",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02383056"
    },
    {
      "nct_id": "NCT07221305",
      "title": "RIIP REPS Neuromuscular Training",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neuromuscular Control",
        "Healthy",
        "Athletic Performance and Injury Risk"
      ],
      "interventions": [
        {
          "name": "Neuromuscular Control Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "14 Years to 18 Years"
      },
      "enrollment_count": 19,
      "start_date": "2023-07-02",
      "completion_date": "2023-10-29",
      "has_results": false,
      "last_update_posted_date": "2025-10-30",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07221305"
    },
    {
      "nct_id": "NCT02643524",
      "title": "Weight Change With Controlled Ankle Movement (CAM) Walker Boot Use",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foot Injury",
        "Ankle Injury"
      ],
      "interventions": [
        {
          "name": "Nutrition and Exercise Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Nell Blake, DPM",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2015-12-07",
      "completion_date": "2019-05-23",
      "has_results": false,
      "last_update_posted_date": "2019-06-28",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02643524"
    },
    {
      "nct_id": "NCT00951080",
      "title": "SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic Wounds",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ulcers",
        "Wounds"
      ],
      "interventions": [
        {
          "name": "Traditional NPWT System",
          "type": "DEVICE"
        },
        {
          "name": "SNaP Wound Care System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "3M",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2009-07",
      "completion_date": "2011-03",
      "has_results": true,
      "last_update_posted_date": "2022-08-01",
      "last_synced_at": "2026-06-11T05:39:08.337Z",
      "location_count": 17,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 14 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Poway",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00951080"
    }
  ]
}