{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Muscle+Strength&page=2",
    "query": {
      "condition": "Lower Extremity Muscle Strength",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Muscle+Strength&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T20:51:48.971Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01080703",
      "title": "To Determine if a Lower Extremity Strengthening Program Improve Quadriceps Muscle Strength",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2010-03",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2014-12-04",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01080703"
    },
    {
      "nct_id": "NCT02584452",
      "title": "Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rupture of Anterior Cruciate Ligament",
        "Tear of Anterior Cruciate Ligament"
      ],
      "interventions": [
        {
          "name": "Mepivacaine",
          "type": "DRUG"
        },
        {
          "name": "adductor canal continuous nerve catheter",
          "type": "PROCEDURE"
        },
        {
          "name": "Normal Saline as bolus followed by bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "adductor canal nerve block",
          "type": "PROCEDURE"
        },
        {
          "name": "ropivacaine and dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Propofol",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 59,
      "start_date": "2015-11-03",
      "completion_date": "2018-04-10",
      "has_results": true,
      "last_update_posted_date": "2019-12-11",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02584452"
    },
    {
      "nct_id": "NCT02065518",
      "title": "Electromyostimulation and Strength Walking for Knee Injuries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injury"
      ],
      "interventions": [
        {
          "name": "NMES",
          "type": "DEVICE"
        },
        {
          "name": "Strength Walking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Rehabilitation Protocol",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 78,
      "start_date": "2014-03",
      "completion_date": "2018-08",
      "has_results": true,
      "last_update_posted_date": "2019-08-28",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 2,
      "location_summary": "Andrews Air Force Base, Maryland • Bethesda, Maryland",
      "locations": [
        {
          "city": "Andrews Air Force Base",
          "state": "Maryland"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02065518"
    },
    {
      "nct_id": "NCT01614392",
      "title": "Lower Extremity Muscle and Function in the Elderly: Study 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mobility Limitation"
      ],
      "interventions": [
        {
          "name": "High velocity low force Power Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low velocity high force Power Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "70 Years to 85 Years"
      },
      "enrollment_count": 52,
      "start_date": "2009-09",
      "completion_date": "2011-10",
      "has_results": true,
      "last_update_posted_date": "2018-12-10",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01614392"
    },
    {
      "nct_id": "NCT01555567",
      "title": "Electrical Stimulation and Eccentric Exercise for Anterior Cruciate Ligament (ACL) Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury"
      ],
      "interventions": [
        {
          "name": "Electrical Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Eccentric Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 43,
      "start_date": "2009-08",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01555567"
    },
    {
      "nct_id": "NCT03141801",
      "title": "Blood Flow Restriction to Improve Muscle Strength After ACL Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury"
      ],
      "interventions": [
        {
          "name": "DELFI PTS Personalized Tourniquet System for Blood Flow Restriction Training",
          "type": "DEVICE"
        },
        {
          "name": "Eccentric Exercise with BLAST Leg Press System",
          "type": "OTHER"
        },
        {
          "name": "Concentric Exercise with BLAST Leg Press System",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "14 Years to 30 Years"
      },
      "enrollment_count": 48,
      "start_date": "2016-08-25",
      "completion_date": "2018-11-21",
      "has_results": false,
      "last_update_posted_date": "2019-01-23",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03141801"
    },
    {
      "nct_id": "NCT01943513",
      "title": "A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "BIIB023",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Biogen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "MALE",
        "summary": "18 Years to 35 Years · Male only"
      },
      "enrollment_count": 34,
      "start_date": "2013-10",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2014-09-03",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "Evansville, Indiana",
      "locations": [
        {
          "city": "Evansville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01943513"
    },
    {
      "nct_id": "NCT06089057",
      "title": "Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Extremity Muscle Strength"
      ],
      "interventions": [
        {
          "name": "Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control for Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 30,
      "start_date": "2026-07-08",
      "completion_date": "2029-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06089057"
    },
    {
      "nct_id": "NCT03983070",
      "title": "The Effects of Lower Extremity Blood Flow Restriction Training on Power, and Muscle Size.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Seated Rowing Ergometer",
          "type": "OTHER"
        },
        {
          "name": "Deadlift",
          "type": "OTHER"
        },
        {
          "name": "Blood flow restriction",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Campbell University, Incorporated",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 20,
      "start_date": "2019-06-01",
      "completion_date": "2021-01-01",
      "has_results": false,
      "last_update_posted_date": "2022-03-14",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "Buies Creek, North Carolina",
      "locations": [
        {
          "city": "Buies Creek",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03983070"
    },
    {
      "nct_id": "NCT07223320",
      "title": "HABIT-ILE + FST in Children With SMA",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "SMA - Spinal Muscular Atrophy"
      ],
      "interventions": [
        {
          "name": "Combined Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) + functional strength training (FST)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Teachers College, Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "5 Years to 17 Years"
      },
      "enrollment_count": 5,
      "start_date": "2025-10-01",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-06-10T20:51:48.971Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223320"
    }
  ]
}