{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Musculoskeletal+Injury&page=4",
    "query": {
      "condition": "Lower Extremity Musculoskeletal Injury",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 134,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Musculoskeletal+Injury&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Musculoskeletal+Injury&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T10:57:36.858Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04163445",
      "title": "Comparison of TKAs Using Force Plate Analysis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Total Knee Arthroplasty",
        "Knee Injuries",
        "Knee Arthritis"
      ],
      "interventions": [
        {
          "name": "MicroPort Orthopedics EVOLUTION Medial Pivot TKA",
          "type": "DEVICE"
        },
        {
          "name": "Depuy Synthes ATTUNE PCR TKA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Russell Nevins, M.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2020-11-11",
      "completion_date": "2022-11",
      "has_results": false,
      "last_update_posted_date": "2021-08-06",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04163445"
    },
    {
      "nct_id": "NCT07721220",
      "title": "Acute Effects of Neurodynamics on Strength and Endurance in Athletes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sciatic Leg Pain",
        "Hamstring Muscle Tightness",
        "Hamstring Muscle Strain",
        "Hamstring Muscle Strength",
        "Hamstring Injuries",
        "Hamstring Injury Prevention",
        "Hamstring Rupture",
        "Sciatic Nerve Injury",
        "Sciatic Radiculopathy",
        "Lumbar Disc Herniation With Radiculopathy",
        "Lumbar Disc Herniation"
      ],
      "interventions": [
        {
          "name": "Sciatic Slider",
          "type": "OTHER"
        },
        {
          "name": "Sciatic Tensioner",
          "type": "OTHER"
        },
        {
          "name": "Mechanically loaded neurodynamic sciatic floss",
          "type": "OTHER"
        },
        {
          "name": "Elastic Resistance Band",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "High Point University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 45,
      "start_date": "2026-06-15",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07721220"
    },
    {
      "nct_id": "NCT04536103",
      "title": "Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bone Diseases, Infectious",
        "Musculoskeletal Diseases",
        "Joint Diseases",
        "Osteoarthritis",
        "ACL Tear",
        "Cartilage Degeneration"
      ],
      "interventions": [
        {
          "name": "MRI",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Xiaojuan Li",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 88,
      "start_date": "2022-04-01",
      "completion_date": "2026-12-28",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04536103"
    },
    {
      "nct_id": "NCT05669066",
      "title": "Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthropathy of Knee",
        "Osteo Arthritis Knee",
        "Osteonecrosis",
        "Meditation",
        "Knee Osteoarthritis",
        "Knee Disease",
        "Knee Injuries",
        "Opioid Use",
        "Opioid Dependence",
        "Opioid Use Disorder"
      ],
      "interventions": [
        {
          "name": "Mindful meditation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 29,
      "start_date": "2017-07-10",
      "completion_date": "2021-12-16",
      "has_results": false,
      "last_update_posted_date": "2022-12-30",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05669066"
    },
    {
      "nct_id": "NCT07256808",
      "title": "Medial Tibial Stress Syndrome Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Medial Tibial Stress Syndrome"
      ],
      "interventions": [
        {
          "name": "Resistance Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rowan University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 26,
      "start_date": "2023-09-14",
      "completion_date": "2024-02-14",
      "has_results": false,
      "last_update_posted_date": "2025-12-01",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 1,
      "location_summary": "Glassboro, New Jersey",
      "locations": [
        {
          "city": "Glassboro",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07256808"
    },
    {
      "nct_id": "NCT04925791",
      "title": "Does Limb Pre-Conditioning Reduce Pain After Hip Arthroscopy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hip Injuries",
        "Hip Dislocation",
        "Hip Fractures"
      ],
      "interventions": [
        {
          "name": "standardized pre-conditioning treatment",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Partial occlusion",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 68,
      "start_date": "2021-10-18",
      "completion_date": "2023-10-20",
      "has_results": false,
      "last_update_posted_date": "2024-08-20",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04925791"
    },
    {
      "nct_id": "NCT05144191",
      "title": "Insignia™ Hip Stem Outcomes Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hip Osteoarthritis",
        "Avascular Necrosis",
        "Rheumatoid Arthritis",
        "Post-traumatic Osteoarthritis",
        "Femoral Neck Fractures",
        "Trochanteric Fractures",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Insignia uncemented Hip Stem",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 313,
      "start_date": "2022-02-07",
      "completion_date": "2034-04-02",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 11,
      "location_summary": "Phoenix, Arizona • San Francisco, California • Chicago, Illinois + 8 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Reno",
          "state": "Nevada"
        },
        {
          "city": "Great Neck",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05144191"
    },
    {
      "nct_id": "NCT06635668",
      "title": "Baseline ACL Injury Risk Screening and Normative Data",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ACL Injury",
        "Anterior Cruciate Ligament Injuries",
        "Musculoskeletal Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Sanford Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "10 Years to 65 Years"
      },
      "enrollment_count": 5000,
      "start_date": "2022-07-19",
      "completion_date": "2033-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 1,
      "location_summary": "Fargo, North Dakota",
      "locations": [
        {
          "city": "Fargo",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06635668"
    },
    {
      "nct_id": "NCT06293469",
      "title": "Accelerated Flap Coverage in Severe Lower Extremity Trauma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Open Tibia Fracture",
        "Open Dislocation of Ankle",
        "Extremity Fracture Lower",
        "Extremity Injuries Lower"
      ],
      "interventions": [
        {
          "name": "Accelerated Flap Coverage Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of Care Flap Timing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 356,
      "start_date": "2024-11-04",
      "completion_date": "2030-02",
      "has_results": false,
      "last_update_posted_date": "2026-09-18",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 7,
      "location_summary": "Sacramento, California • Baltimore, Maryland • Largo, Maryland + 2 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Largo",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06293469"
    },
    {
      "nct_id": "NCT04537013",
      "title": "Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries",
        "Cartilage Injury",
        "Cartilage Disease",
        "Knee Discomfort"
      ],
      "interventions": [
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        },
        {
          "name": "Microfracture plus placement of Chondro-Gide® ACC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Geistlich Pharma AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 82,
      "start_date": "2020-08-26",
      "completion_date": "2025-09-29",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-10-06T10:57:36.858Z",
      "location_count": 3,
      "location_summary": "Phoenix, Arizona • Stamford, Connecticut • Johns Creek, Georgia",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Stamford",
          "state": "Connecticut"
        },
        {
          "city": "Johns Creek",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04537013"
    }
  ]
}