{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Ulcer&page=2",
    "query": {
      "condition": "Lower Extremity Ulcer",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+Ulcer&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-25T02:17:10.993Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05291169",
      "title": "Omeza Combination Therapy With Standard of Care to Standard of Care Alone for Chronic Venous Leg Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Omeza® OCM™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Omeza, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2022-04-11",
      "completion_date": "2024-03-01",
      "has_results": false,
      "last_update_posted_date": "2024-06-06",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 7,
      "location_summary": "Los Angeles, California • Hollywood, Florida • North Port, Florida + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "North Port",
          "state": "Florida"
        },
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        },
        {
          "city": "Ford City",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05291169"
    },
    {
      "nct_id": "NCT06560502",
      "title": "Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Venous Leg Ulcer",
        "Ulcer Foot",
        "Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Standard of Care-DFU",
          "type": "OTHER"
        },
        {
          "name": "AmnioCore - DFU",
          "type": "OTHER"
        },
        {
          "name": "Amnio Quad-Core - DFU",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care-VLU",
          "type": "OTHER"
        },
        {
          "name": "Amnio Tri-Core - VLU",
          "type": "OTHER"
        },
        {
          "name": "Amniocore Pro +",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stability Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 324,
      "start_date": "2024-08-01",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-01-20",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 1,
      "location_summary": "Circleville, Ohio",
      "locations": [
        {
          "city": "Circleville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06560502"
    },
    {
      "nct_id": "NCT04920253",
      "title": "Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Venous Leg Ulcer",
        "Surgical Wound Dehiscence",
        "Traumatic Wounds"
      ],
      "interventions": [
        {
          "name": "Study Device Debridement",
          "type": "DEVICE"
        },
        {
          "name": "SOC Debridement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medaxis, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2021-11-29",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2024-11-21",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 1,
      "location_summary": "Bradenton, Florida",
      "locations": [
        {
          "city": "Bradenton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04920253"
    },
    {
      "nct_id": "NCT01408277",
      "title": "Using Santyl on Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot Ulcers",
        "Diabetic Foot Wounds"
      ],
      "interventions": [
        {
          "name": "Santyl",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Control",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Healthpoint",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 55,
      "start_date": "2011-08",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2014-07-24",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 7,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • Southfield, Michigan + 3 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Southfield",
          "state": "Michigan"
        },
        {
          "city": "Summit",
          "state": "New Jersey"
        },
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01408277"
    },
    {
      "nct_id": "NCT04901013",
      "title": "Clinical Study Of Affinity Versus SOC In The Management Of VLUs",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Affinity",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Organogenesis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-06-14",
      "completion_date": "2023-06",
      "has_results": false,
      "last_update_posted_date": "2021-09-08",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 1,
      "location_summary": "Carlsbad, California",
      "locations": [
        {
          "city": "Carlsbad",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04901013"
    },
    {
      "nct_id": "NCT06487780",
      "title": "Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot",
        "Diabetic Foot Ulcer",
        "Foot Ulcer, Diabetic",
        "Foot Wound"
      ],
      "interventions": [
        {
          "name": "Lifestyle-focused Occupational Therapy Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-06-11",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-22",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 3,
      "location_summary": "Downey, California • Los Angeles, California",
      "locations": [
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06487780"
    },
    {
      "nct_id": "NCT01898923",
      "title": "Evaluate the Efficacy and Safety of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetic Foot"
      ],
      "interventions": [
        {
          "name": "ON101 Cream",
          "type": "DRUG"
        },
        {
          "name": "Aquacel® Hydrofiber® dressing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Oneness Biotech Co., Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "20 Years to 80 Years"
      },
      "enrollment_count": 236,
      "start_date": "2012-11-23",
      "completion_date": "2020-05-11",
      "has_results": true,
      "last_update_posted_date": "2021-04-14",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 1,
      "location_summary": "Fresno, California",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01898923"
    },
    {
      "nct_id": "NCT04647240",
      "title": "MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Venous Stasis Ulcer",
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "MTX-001 (human amniotic fluid)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Merakris Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2022-02-26",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 11,
      "location_summary": "Tucson, Arizona • Castro Valley, California • Fresno, California + 7 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04647240"
    },
    {
      "nct_id": "NCT01552447",
      "title": "Human Amniotic Membrane Grafting and Standard of Care Versus Standard of Care Alone in the Treatment of Venous Leg Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "EpiFix",
          "type": "OTHER"
        },
        {
          "name": "Compression Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "MiMedx Group, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 98,
      "start_date": "2012-03",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2016-03-16",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 5,
      "location_summary": "Boca Raton, Florida • Framingham, Massachusetts • Tulsa, Oklahoma + 2 more",
      "locations": [
        {
          "city": "Boca Raton",
          "state": "Florida"
        },
        {
          "city": "Framingham",
          "state": "Massachusetts"
        },
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        },
        {
          "city": "Erie",
          "state": "Pennsylvania"
        },
        {
          "city": "Kittanning",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01552447"
    },
    {
      "nct_id": "NCT04723134",
      "title": "Evaluation of a Folic Acid Wound Treatment (FAWT) for Chronic, Early-Stage Diabetic Foot Ulcer (DFU) Healing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "Folinic acid calcium salt",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Joseph Boykin, MD",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2021-12-01",
      "completion_date": "2024-09-24",
      "has_results": false,
      "last_update_posted_date": "2024-10-04",
      "last_synced_at": "2026-07-25T02:17:10.993Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04723134"
    }
  ]
}