{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+or+Diabetic+Foot+Ulcers&page=2",
    "query": {
      "condition": "Lower Extremity or Diabetic Foot Ulcers",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Extremity+or+Diabetic+Foot+Ulcers&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T11:47:44.487Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02209051",
      "title": "Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "AMNIOEXCEL",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care, Diabetic Foot Ulcers",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2014-07",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2017-12-02",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 8,
      "location_summary": "Phoenix, Arizona • Castro Valley, California • Stockton, California + 5 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Stockton",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "North Miami Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02209051"
    },
    {
      "nct_id": "NCT06939686",
      "title": "Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers (DFUs)",
        "Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)"
      ],
      "interventions": [
        {
          "name": "Miro3D Wound Matrix",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care (SOC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Reprise Biomedical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-11-01",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 3,
      "location_summary": "Coconut Creek, Florida • Tamarac, Florida • New York, New York",
      "locations": [
        {
          "city": "Coconut Creek",
          "state": "Florida"
        },
        {
          "city": "Tamarac",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06939686"
    },
    {
      "nct_id": "NCT02581488",
      "title": "Use of Santyl in Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot",
        "Foot Ulcer, Diabetic"
      ],
      "interventions": [
        {
          "name": "Santyl",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Product containing silver",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2015-10",
      "completion_date": "2017-01-12",
      "has_results": true,
      "last_update_posted_date": "2018-08-01",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 11,
      "location_summary": "Sylmar, California • Melbourne, Florida • Baltimore, Maryland + 8 more",
      "locations": [
        {
          "city": "Sylmar",
          "state": "California"
        },
        {
          "city": "Melbourne",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02581488"
    },
    {
      "nct_id": "NCT01830348",
      "title": "Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "DSC127",
          "type": "DRUG"
        },
        {
          "name": "placebo vehicle gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 266,
      "start_date": "2013-02",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2017-12-12",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 25,
      "location_summary": "Mobile, Alabama • Fair Oaks, California • Fresno, California + 22 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Fair Oaks",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Pismo Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01830348"
    },
    {
      "nct_id": "NCT01849965",
      "title": "Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "DSC127",
          "type": "DRUG"
        },
        {
          "name": "placebo vehicle gel",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care gel, Aquasite",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 396,
      "start_date": "2013-04",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2017-12-12",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 33,
      "location_summary": "Mesa, Arizona • Phoenix, Arizona • Castro Valley, California + 25 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01849965"
    },
    {
      "nct_id": "NCT07046767",
      "title": "CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Venous Leg Ulcer",
        "Wound; Foot"
      ],
      "interventions": [
        {
          "name": "IP1: BioLab Membrane Wrap Lite IP2: BioLab Tri-Membrane Wrap",
          "type": "OTHER"
        },
        {
          "name": "IP2: BioLab Tri-Membrane Wrap",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Capsicure, LLC",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 165,
      "start_date": "2025-10-01",
      "completion_date": "2026-07-20",
      "has_results": false,
      "last_update_posted_date": "2025-10-22",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 7,
      "location_summary": "Oxnard, California • Coral Gables, Florida • Miami, Florida + 4 more",
      "locations": [
        {
          "city": "Oxnard",
          "state": "California"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07046767"
    },
    {
      "nct_id": "NCT00971048",
      "title": "Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers",
        "Pressure Ulcers"
      ],
      "interventions": [
        {
          "name": "HP828-101",
          "type": "DEVICE"
        },
        {
          "name": "Hydrogel/Hydrocolloid",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Healthpoint",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 88,
      "start_date": "2009-09",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2014-01-27",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 11,
      "location_summary": "Bakersfield, California • Chula Vista, California • Fresno, California + 7 more",
      "locations": [
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00971048"
    },
    {
      "nct_id": "NCT01840085",
      "title": "Open-Label Study in Diabetic Foot Ulcers (DFU), to Evaluate Safety of 0.03% DSC127 Topical Gel in Chronic Use",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "0.03% DSC127 topical gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 261,
      "start_date": "2015-12",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2017-12-12",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 21,
      "location_summary": "Mobile, Alabama • Chino, California • Fresno, California + 16 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Chino",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01840085"
    },
    {
      "nct_id": "NCT02294175",
      "title": "Larval Debridement Therapy Versus Sharp Debridement to Remove Biofilm",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Extremity or Diabetic Foot Ulcers",
        "Bacterial Infection"
      ],
      "interventions": [
        {
          "name": "Larval Debridement Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Bedside Sharp Debridement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "North Florida Foundation for Research and Education",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2015-01",
      "completion_date": "2018-03-24",
      "has_results": true,
      "last_update_posted_date": "2020-04-07",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 2,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02294175"
    },
    {
      "nct_id": "NCT06810726",
      "title": "Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Type 1 Diabetes Mellitus",
        "Type 2 Diabetes Mellitus (T2DM)",
        "Neuroischemic Foot Ulcer",
        "Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)",
        "Chronic Wound Care"
      ],
      "interventions": [
        {
          "name": "Platelet Rich Plasma",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Estar Medical dba Medical Technologies, LTD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-04-15",
      "completion_date": "2026-08-15",
      "has_results": false,
      "last_update_posted_date": "2025-06-12",
      "last_synced_at": "2026-07-24T11:47:44.487Z",
      "location_count": 2,
      "location_summary": "Corpus Christi, Texas",
      "locations": [
        {
          "city": "Corpus Christi",
          "state": "Texas"
        },
        {
          "city": "Corpus Christi",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06810726"
    }
  ]
}