{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Limb+Amputation&page=2",
    "query": {
      "condition": "Lower Limb Amputation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Limb+Amputation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T17:54:09.269Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05560061",
      "title": "An Uneven Terrain Surface to Improve Locomotor Robustness in People With Amputation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Gait practice on an uneven terrain surface",
          "type": "OTHER"
        },
        {
          "name": "Gait practice on a flat terrain surface",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Nevada, Las Vegas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2022-07-01",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05560061"
    },
    {
      "nct_id": "NCT05267639",
      "title": "Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Amputation; Traumatic, Leg, Lower",
        "Limb; Absence, Congenital, Lower",
        "Prosthesis User",
        "Lower Limb Amputation Above Knee (Injury)",
        "Amputation; Traumatic, Leg: Thigh, Between Hip and Knee"
      ],
      "interventions": [
        {
          "name": "Power Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Liberating Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2022-05-01",
      "completion_date": "2024-08-28",
      "has_results": true,
      "last_update_posted_date": "2025-06-26",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 2,
      "location_summary": "Holliston, Massachusetts • Austin, Texas",
      "locations": [
        {
          "city": "Holliston",
          "state": "Massachusetts"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05267639"
    },
    {
      "nct_id": "NCT05119192",
      "title": "Dual-tasking for Individuals With Lower Limb Amputation: Exploring the Relationship to Falls and Instrumental Activities of Daily Living",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amputation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "50 Years to 89 Years"
      },
      "enrollment_count": 48,
      "start_date": "2021-12-01",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-03-15",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05119192"
    },
    {
      "nct_id": "NCT04616378",
      "title": "Design, Prototyping, and Testing of a Robotic Prosthetic Leg",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation; Traumatic, Leg, Lower"
      ],
      "interventions": [
        {
          "name": "Phase 2 Prescribed Prosthesis",
          "type": "OTHER"
        },
        {
          "name": "Phase 2 Robotic Prosthetic Leg",
          "type": "OTHER"
        },
        {
          "name": "Phase 3 No Prosthesis",
          "type": "OTHER"
        },
        {
          "name": "Phase 3 Robotic Prosthetic Leg",
          "type": "OTHER"
        },
        {
          "name": "Phase 3 Prescribed Prosthesis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 2,
      "start_date": "2021-02-01",
      "completion_date": "2022-03-30",
      "has_results": false,
      "last_update_posted_date": "2022-08-29",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04616378"
    },
    {
      "nct_id": "NCT05884203",
      "title": "Improving Prosthetic Provision in Rural Communities: Limb Scanning With Caregiver Assistance",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Extremity Amputation"
      ],
      "interventions": [
        {
          "name": "Caregiver socket",
          "type": "DEVICE"
        },
        {
          "name": "Prosthetist socket",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 25,
      "start_date": "2023-07-01",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05884203"
    },
    {
      "nct_id": "NCT03338842",
      "title": "Virtual Reality Treatment for Phantom Limb Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Above Knee (Injury)",
        "Lower Limb Amputation Below Knee (Injury)",
        "Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Distractor and Lower limb VR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2018-01-12",
      "completion_date": "2019-11-01",
      "has_results": false,
      "last_update_posted_date": "2020-06-16",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03338842"
    },
    {
      "nct_id": "NCT00932399",
      "title": "Longitudinal Study of Weight Change Following Lower Limb Amputation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amputation Wound",
        "Traumatic Amputation of Toe",
        "Dysvascular Amputation of Lower Limb"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "27 Years",
        "maximum_age": "89 Years",
        "sex": "MALE",
        "summary": "27 Years to 89 Years · Male only"
      },
      "enrollment_count": 4549,
      "start_date": "2010-03",
      "completion_date": "2016-01",
      "has_results": true,
      "last_update_posted_date": "2016-02-08",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00932399"
    },
    {
      "nct_id": "NCT03550118",
      "title": "Auto Control of Volume Management for Limb Loss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Amputation Below Knee (Injury)"
      ],
      "interventions": [
        {
          "name": "Adjustable socket",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2015-08-07",
      "completion_date": "2022-01",
      "has_results": true,
      "last_update_posted_date": "2023-05-03",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03550118"
    },
    {
      "nct_id": "NCT04063592",
      "title": "AMI Construction in Lower Extremity Residual Limbs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Residual limb revision",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 26,
      "start_date": "2020-02-24",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 3,
      "location_summary": "Bethesda, Maryland • Boston, Massachusetts • Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04063592"
    },
    {
      "nct_id": "NCT02632929",
      "title": "Prevention of Amputation in Diabetic Foot Ulcers Using Amniotic Tissue",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boise VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2015-05-30",
      "completion_date": "2019-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-06-10T17:54:09.269Z",
      "location_count": 1,
      "location_summary": "Boise, Idaho",
      "locations": [
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02632929"
    }
  ]
}