{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Limb+Trauma",
    "query": {
      "condition": "Lower Limb Trauma"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 1026,
    "total_pages": 103,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lower+Limb+Trauma&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T06:48:58.531Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00463099",
      "title": "Multicenter Orthopaedics Outcomes Network for ACL Reconstructions",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rupture of Anterior Cruciate Ligament"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "10 Years to 80 Years"
      },
      "enrollment_count": 3294,
      "start_date": "2002-01",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 8,
      "location_summary": "Boulder, Colorado • Iowa City, Iowa • St Louis, Missouri + 5 more",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00463099"
    },
    {
      "nct_id": "NCT02988063",
      "title": "Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Leg Ulcer",
        "Veins, Varicose",
        "Venous Ulcer",
        "Reflux",
        "Venous Reflux",
        "Venous Leg Ulcer",
        "Varicose Veins",
        "Varicose Ulcer",
        "Varicose Veins Leg"
      ],
      "interventions": [
        {
          "name": "Polidocanol Endovenous Microfoam (PEM)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "OhioHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-04-10",
      "completion_date": "2017-09-12",
      "has_results": false,
      "last_update_posted_date": "2017-09-15",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02988063"
    },
    {
      "nct_id": "NCT06681428",
      "title": "Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Chronic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "Allograft",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tides Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2024-11-14",
      "completion_date": "2026-11-18",
      "has_results": false,
      "last_update_posted_date": "2025-02-10",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 9,
      "location_summary": "Fresno, California • Los Angeles, California • Vista, California + 5 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Vista",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06681428"
    },
    {
      "nct_id": "NCT07161830",
      "title": "Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "Omeza® Complete Matrix",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Omeza, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2025-12-04",
      "completion_date": "2027-03-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 10,
      "location_summary": "Evergreen Park, Illinois • Denham Springs, Louisiana • Leesville, Louisiana + 7 more",
      "locations": [
        {
          "city": "Evergreen Park",
          "state": "Illinois"
        },
        {
          "city": "Denham Springs",
          "state": "Louisiana"
        },
        {
          "city": "Leesville",
          "state": "Louisiana"
        },
        {
          "city": "Marksville",
          "state": "Louisiana"
        },
        {
          "city": "Slidell",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07161830"
    },
    {
      "nct_id": "NCT06983184",
      "title": "Menstrual Cycle-Synced Neuromuscular Training",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Injuries"
      ],
      "interventions": [
        {
          "name": "MC-synced NTP",
          "type": "OTHER"
        },
        {
          "name": "Blinded NTP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Sophia Ulman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "19 Years",
        "sex": "FEMALE",
        "summary": "13 Years to 19 Years · Female only"
      },
      "enrollment_count": 148,
      "start_date": "2025-05-01",
      "completion_date": "2027-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 1,
      "location_summary": "Frisco, Texas",
      "locations": [
        {
          "city": "Frisco",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06983184"
    },
    {
      "nct_id": "NCT00058864",
      "title": "The HIP Impact Protection Program (HIP PRO)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hip Fractures"
      ],
      "interventions": [
        {
          "name": "Energy absorbing and distributing trochanteric pad",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Institute on Aging (NIA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "66 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "66 Years and older"
      },
      "enrollment_count": 546,
      "start_date": "2001-09",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2009-02-27",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 4,
      "location_summary": "Baltimore, Maryland • Boston, Massachusetts • St Louis, Missouri",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00058864"
    },
    {
      "nct_id": "NCT03905863",
      "title": "The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Surgical Wound"
      ],
      "interventions": [
        {
          "name": "Natrox® Oxygen Wound Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Inotec AMD Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 145,
      "start_date": "2019-06-04",
      "completion_date": "2020-10-18",
      "has_results": true,
      "last_update_posted_date": "2021-11-22",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 19,
      "location_summary": "Los Angeles, California • Miami, Florida • Miami Lakes, Florida + 15 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami Lakes",
          "state": "Florida"
        },
        {
          "city": "Miami Lakes",
          "state": "Florida"
        },
        {
          "city": "North Miami Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03905863"
    },
    {
      "nct_id": "NCT01816633",
      "title": "Effectiveness of AutoloGel Therapy in Diabetic Foot Ulcers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "AutoloGel",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cytomedix",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2013-10",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2016-10-21",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 2,
      "location_summary": "Arcadia, California • Cumming, Georgia",
      "locations": [
        {
          "city": "Arcadia",
          "state": "California"
        },
        {
          "city": "Cumming",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01816633"
    },
    {
      "nct_id": "NCT01126398",
      "title": "Trauma Expectation Factor Trauma Outcome Measure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ankle Fracture",
        "Pilon Fracture"
      ],
      "interventions": [
        {
          "name": "ankle or distal tibia surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "AO Clinical Investigation and Publishing Documentation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 204,
      "start_date": "2007-02",
      "completion_date": "2010-02",
      "has_results": false,
      "last_update_posted_date": "2021-07-22",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 3,
      "location_summary": "Jacksonville, Florida • New York, New York",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01126398"
    },
    {
      "nct_id": "NCT06024304",
      "title": "InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fracture of Hip"
      ],
      "interventions": [
        {
          "name": "Synthes TFNA",
          "type": "DEVICE"
        },
        {
          "name": "Trigen InterTAN",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Paul E. Matuszewski",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-04-18",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-07-24T06:48:58.531Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06024304"
    }
  ]
}