{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lumbar+Intervertebral+Disc+Herniation",
    "query": {
      "condition": "Lumbar Intervertebral Disc Herniation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 54,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lumbar+Intervertebral+Disc+Herniation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T07:46:36.657Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02421601",
      "title": "A Study of SI-6603 in Patients With Lumbar Disc Herniation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Intervertebral Disc Disease",
        "Lumbar Disc Disease"
      ],
      "interventions": [
        {
          "name": "Condoliase",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seikagaku Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 1011,
      "start_date": "2015-03",
      "completion_date": "2018-02",
      "has_results": true,
      "last_update_posted_date": "2023-03-23",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 30,
      "location_summary": "Mobile, Alabama • Phoenix, Arizona • Gold River, California + 27 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Gold River",
          "state": "California"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Los Gatos",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02421601"
    },
    {
      "nct_id": "NCT05029726",
      "title": "Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Lumbar Spinal Stenosis",
        "Lumbar Disc Herniation",
        "Lumbar Spondylolisthesis",
        "Lumbar Spondylosis",
        "Lumbar Radiculopathy",
        "Lumbar Spine Instability",
        "Synovial Cyst",
        "Degenerative Disc Disease",
        "Degenerative Spondylolisthesis",
        "Degenerative Intervertebral Discs"
      ],
      "interventions": [
        {
          "name": "Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine",
          "type": "DRUG"
        },
        {
          "name": "normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "John O'Toole",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 125,
      "start_date": "2022-02-01",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05029726"
    },
    {
      "nct_id": "NCT01267825",
      "title": "CT Guided Injection for Low Back Radiculopathy: A Randomized Clinical Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Disc Herniation",
        "Lumbosacral Radiculopathy"
      ],
      "interventions": [
        {
          "name": "CT-guided corticosteroid+ bupivicaine",
          "type": "DRUG"
        },
        {
          "name": "Standard medical care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 1,
      "start_date": "2010-09-01",
      "completion_date": "2013-08",
      "has_results": true,
      "last_update_posted_date": "2018-08-31",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01267825"
    },
    {
      "nct_id": "NCT01941563",
      "title": "A Study of SI-6603 in Patients With Lumbar Disc Herniation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Intervertebral Disc Disease",
        "Lumbar Disc Disease"
      ],
      "interventions": [
        {
          "name": "Condoliase",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seikagaku Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 385,
      "start_date": "2013-09",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2023-03-23",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 32,
      "location_summary": "Phoenix, Arizona • Gold River, California • Laguna Hills, California + 29 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Gold River",
          "state": "California"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Los Gatos",
          "state": "California"
        },
        {
          "city": "Murrieta",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01941563"
    },
    {
      "nct_id": "NCT01978912",
      "title": "A Study to Evaluate Safety and Exploratory Efficacy of KTP-001 in Subjects With Lumbar Disc Herniation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Lumbar Disc Herniation"
      ],
      "interventions": [
        {
          "name": "KTP-001",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Teijin America, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2013-02",
      "completion_date": "2018-10-16",
      "has_results": true,
      "last_update_posted_date": "2020-02-11",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Encinitas, California + 6 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Encinitas",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01978912"
    },
    {
      "nct_id": "NCT03514277",
      "title": "A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Low Back Pain",
        "Lumbosacral Radiculopathy",
        "Lumbar Disc Degeneration",
        "Lumbar Disc Herniation",
        "Stenosis",
        "Spondylolisthesis",
        "Spondylolysis",
        "Deformity of Spine"
      ],
      "interventions": [
        {
          "name": "Exparel",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Virtua Health, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2016-12-01",
      "completion_date": "2019-12-31",
      "has_results": true,
      "last_update_posted_date": "2021-01-06",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 1,
      "location_summary": "Mount Holly, New Jersey",
      "locations": [
        {
          "city": "Mount Holly",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03514277"
    },
    {
      "nct_id": "NCT07721220",
      "title": "Acute Effects of Neurodynamics on Strength and Endurance in Athletes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sciatic Leg Pain",
        "Hamstring Muscle Tightness",
        "Hamstring Muscle Strain",
        "Hamstring Muscle Strength",
        "Hamstring Injuries",
        "Hamstring Injury Prevention",
        "Hamstring Rupture",
        "Sciatic Nerve Injury",
        "Sciatic Radiculopathy",
        "Lumbar Disc Herniation With Radiculopathy",
        "Lumbar Disc Herniation"
      ],
      "interventions": [
        {
          "name": "Sciatic Slider",
          "type": "OTHER"
        },
        {
          "name": "Sciatic Tensioner",
          "type": "OTHER"
        },
        {
          "name": "Mechanically loaded neurodynamic sciatic floss",
          "type": "OTHER"
        },
        {
          "name": "Elastic Resistance Band",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "High Point University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 45,
      "start_date": "2026-06-15",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07721220"
    },
    {
      "nct_id": "NCT02441959",
      "title": "Full-Endoscopic vs Open Discectomy for the Treatment of Symptomatic Lumbar Herniated Disc",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Disc Herniation"
      ],
      "interventions": [
        {
          "name": "Lumbar discectomy Open",
          "type": "PROCEDURE"
        },
        {
          "name": "Lumbar discectomy Endoscopic",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2015-06",
      "completion_date": "2018-07",
      "has_results": false,
      "last_update_posted_date": "2018-08-07",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02441959"
    },
    {
      "nct_id": "NCT03986580",
      "title": "Study of Lumbar Discectomy With Annular Closure",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Disc Herniation"
      ],
      "interventions": [
        {
          "name": "Annular closure device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Intrinsic Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 55,
      "start_date": "2020-05-01",
      "completion_date": "2024-12",
      "has_results": false,
      "last_update_posted_date": "2023-09-28",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 7,
      "location_summary": "San Diego, California • Jacksonville, Florida • Evanston, Illinois + 4 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Carmel",
          "state": "Indiana"
        },
        {
          "city": "Paducah",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03986580"
    },
    {
      "nct_id": "NCT06525896",
      "title": "Non-surgical Spinal Decompression Therapy and Outcomes",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Herniation, Disc",
        "Sciatic Radiculopathy",
        "Intervertebral Disc Stenosis of Neural Canal",
        "Intervertebral Disc Injury"
      ],
      "interventions": [
        {
          "name": "NSSD",
          "type": "DEVICE"
        },
        {
          "name": "Sham NSSD",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 42,
      "start_date": "2025-01-07",
      "completion_date": "2026-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-09-25T07:46:36.657Z",
      "location_count": 2,
      "location_summary": "Stanford, California • Tampa, Florida",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06525896"
    }
  ]
}