{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lumbar+Spine+Disc+Degeneration",
    "query": {
      "condition": "Lumbar Spine Disc Degeneration"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 53,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lumbar+Spine+Disc+Degeneration&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T15:57:49.531Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03928041",
      "title": "A Clinical Study to Evaluate Safety and Performance of PEEK-OPTIMA™ HA Enhanced Interbody Cages in the Lumbar Spine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease Lumbar",
        "Spondylolisthesis, Grade 1"
      ],
      "interventions": [
        {
          "name": "Device: EVOS Lumbar Interbody System (EVOS-HA)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Invibio Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2019-06-27",
      "completion_date": "2023-09-25",
      "has_results": false,
      "last_update_posted_date": "2025-04-30",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 2,
      "location_summary": "Charlotte, North Carolina • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03928041"
    },
    {
      "nct_id": "NCT01861743",
      "title": "Multimodal Analgesia Versus Routine Care Pain Management",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease Lumbar",
        "Spinal Stenosis",
        "Lumbar Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "Multimodal Analgesia",
          "type": "OTHER"
        },
        {
          "name": "Patient controlled analgesia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 42,
      "start_date": "2013-04",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-08-29",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01861743"
    },
    {
      "nct_id": "NCT07367139",
      "title": "Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spine Health",
        "Spine Injuries and Disorders",
        "Spine Degeneration",
        "Whole Body Vibration"
      ],
      "interventions": [
        {
          "name": "Water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Milwaukee VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "20 Years to 45 Years"
      },
      "enrollment_count": 112,
      "start_date": "2026-07-01",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-26",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07367139"
    },
    {
      "nct_id": "NCT01721889",
      "title": "Radiostereometric Analysis of Spine Arthrodesis",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lumbar Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "Radiostereometric Analysis",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "OAD Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2012-11",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2013-06-11",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 1,
      "location_summary": "Warrenville, Illinois",
      "locations": [
        {
          "city": "Warrenville",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01721889"
    },
    {
      "nct_id": "NCT04679896",
      "title": "Post Marketing Study of MagnetOs Putty Compared to Local Autograft in Patients Undergoing Posterolateral Lumbar Fusion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spine Fusion"
      ],
      "interventions": [
        {
          "name": "MagnetOs Putty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Kuros Biosurgery AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2021-08-13",
      "completion_date": "2023-12-02",
      "has_results": false,
      "last_update_posted_date": "2024-02-13",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 1,
      "location_summary": "Paducah, Kentucky",
      "locations": [
        {
          "city": "Paducah",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04679896"
    },
    {
      "nct_id": "NCT02808234",
      "title": "Study of Nucel for One and Two Level Lumbar Interbody Fusion",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spondylolisthesis",
        "Spondylosis"
      ],
      "interventions": [
        {
          "name": "One or two level lumbar interbody fusion surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Nucel",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Organogenesis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 200,
      "start_date": "2015-12",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2021-05-26",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 3,
      "location_summary": "Tampa, Florida • Shreveport, Louisiana • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02808234"
    },
    {
      "nct_id": "NCT04421209",
      "title": "Analgesic Effects of Perioperative Propranolol Administration for Spine Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lumbar Disc Disease",
        "Spinal Fusion",
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "Propranolol Hcl 40mg Tab",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-12",
      "completion_date": "2021-09-30",
      "has_results": false,
      "last_update_posted_date": "2021-03-16",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04421209"
    },
    {
      "nct_id": "NCT02070484",
      "title": "Human Amniotic Tissue-derived Allograft, NuCel, in Posteriolateral Lumbar Fusions for Degenerative Disc Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Degenerative Disc Disease",
        "Spinal Stenosis",
        "Spondylolisthesis",
        "Spondylosis",
        "Intervertebral Disk Displacement",
        "Intervertebral Disk Degeneration",
        "Spinal Diseases",
        "Bone Diseases",
        "Musculoskeletal Diseases",
        "Spondylolysis"
      ],
      "interventions": [
        {
          "name": "NuCel",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Demineralized Bone Matrix",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "OhioHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 6,
      "start_date": "2014-02",
      "completion_date": "2017-03-24",
      "has_results": true,
      "last_update_posted_date": "2018-09-28",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02070484"
    },
    {
      "nct_id": "NCT02225444",
      "title": "A Prospective Study of Instrumented, Posterolateral Lumbar Fusions (PLF) With OsteoAMP®",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spondylolisthesis",
        "Scoliosis",
        "Intervertebral Disc Disease"
      ],
      "interventions": [
        {
          "name": "OsteoAMP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Bioventus LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 42,
      "start_date": "2015-11-19",
      "completion_date": "2019-10-11",
      "has_results": false,
      "last_update_posted_date": "2020-11-05",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 9,
      "location_summary": "New Haven, Connecticut • Chicago, Illinois • Kansas City, Kansas + 6 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Paducah",
          "state": "Kentucky"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02225444"
    },
    {
      "nct_id": "NCT01771471",
      "title": "A Study Comparing the Safety and Effectiveness of Cartilage Cell Injected Into the Lumbar Disc as Compared to a Placebo",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "NuQu",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "ISTO Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2012-11",
      "completion_date": "2020-09",
      "has_results": false,
      "last_update_posted_date": "2017-08-31",
      "last_synced_at": "2026-07-22T15:57:49.531Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • San Francisco, California • Santa Monica, California + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Macon",
          "state": "Georgia"
        },
        {
          "city": "Newton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01771471"
    }
  ]
}