{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lumbar+Spine+Pathology",
    "query": {
      "condition": "Lumbar Spine Pathology"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 87,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lumbar+Spine+Pathology&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T10:03:17.232Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03133845",
      "title": "Shaping Anesthetic Techniques to Reduce Post-operative Delirium",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium",
        "Lumbar Radiculopathy",
        "Lumbar Osteoarthritis",
        "Lumbar Spine Disc Degeneration"
      ],
      "interventions": [
        {
          "name": "Light sedation with propofol",
          "type": "PROCEDURE"
        },
        {
          "name": "Induction with propofol",
          "type": "PROCEDURE"
        },
        {
          "name": "Maintenance anesthetic using a volatile anesthetic",
          "type": "PROCEDURE"
        },
        {
          "name": "Muscle relaxant during maintenance anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Pain control with fentanyl",
          "type": "PROCEDURE"
        },
        {
          "name": "Bispectral Index (BIS) monitoring for depth of anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Spinal Anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Midazolam administered during spinal anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Cerebrospinal fluid collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Administration of intrathecal morphine",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 218,
      "start_date": "2015-10",
      "completion_date": "2020-05-25",
      "has_results": false,
      "last_update_posted_date": "2020-06-18",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03133845"
    },
    {
      "nct_id": "NCT00529997",
      "title": "Dynamic Stabilization for Lumbar Spinal Stenosis With Stabilimax NZ® Dynamic Spine Stabilization System",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "Stabilimax NZ® Dynamic Spine Stabilization System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Applied Spine Technologies",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 480,
      "start_date": "2007-02",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2010-08-11",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 19,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Oceanside, California + 16 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oceanside",
          "state": "California"
        },
        {
          "city": "Littleton",
          "state": "Colorado"
        },
        {
          "city": "New Britain",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00529997"
    },
    {
      "nct_id": "NCT07479199",
      "title": "Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Thoracic Neoplasms",
        "Lumbar Neoplasm"
      ],
      "interventions": [
        {
          "name": "kyphoplasty with Osteocool",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2026-03-16",
      "completion_date": "2031-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-23",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07479199"
    },
    {
      "nct_id": "NCT06653920",
      "title": "Clinical Correlates of Pressure Pain Thresholds in Back and Leg Pain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Segmental Dysfunction of the Lumbar Spine",
        "Back Pain",
        "Leg Pain"
      ],
      "interventions": [
        {
          "name": "Chiropractic",
          "type": "OTHER"
        },
        {
          "name": "Exercise",
          "type": "OTHER"
        },
        {
          "name": "Cryotherapy",
          "type": "OTHER"
        },
        {
          "name": "Spinalator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Leach Chiropractic Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 98,
      "start_date": "2018-01-01",
      "completion_date": "2023-10-09",
      "has_results": false,
      "last_update_posted_date": "2024-10-22",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Starkville, Mississippi",
      "locations": [
        {
          "city": "Starkville",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06653920"
    },
    {
      "nct_id": "NCT04058665",
      "title": "Hemostatic Agent Use and Intraoperative Blood Loss in Lumbar Spine Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Blood Loss"
      ],
      "interventions": [
        {
          "name": "Floseal",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2019-06-18",
      "completion_date": "2022-03-01",
      "has_results": false,
      "last_update_posted_date": "2023-04-14",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04058665"
    },
    {
      "nct_id": "NCT00231374",
      "title": "Measure of Cerebrospinal Fluid (CSF) Pressure Variation With Patient Positioning",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Back Pain"
      ],
      "interventions": [
        {
          "name": "Myelogram",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 0,
      "start_date": "2005-09",
      "completion_date": "2007-09",
      "has_results": false,
      "last_update_posted_date": "2014-01-09",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00231374"
    },
    {
      "nct_id": "NCT03059602",
      "title": "Biopsychosocial Impact on Caregivers in Patients Undergoing Joint and Spine Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "No specific treatment based intervention-health measurement instrument",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Defense and Veterans Center for Integrative Pain Management",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 150,
      "start_date": "2016-05-12",
      "completion_date": "2018-10-30",
      "has_results": false,
      "last_update_posted_date": "2019-07-17",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03059602"
    },
    {
      "nct_id": "NCT06528288",
      "title": "Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fusion of Spine, Lumbar Region",
        "Anesthesia, Local",
        "Pain, Postoperative",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Erector Spinae Plane Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Subcutaneous Anesthesia",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Massachusetts, Worcester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2024-09-13",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06528288"
    },
    {
      "nct_id": "NCT06173401",
      "title": "Comparing SingLe- Vs Multi-Fraction Spine STereotActic Radiosurgery in Spinal Metastases",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Spinal Metastases"
      ],
      "interventions": [
        {
          "name": "Single-fraction spine SRS",
          "type": "RADIATION"
        },
        {
          "name": "Multi-fraction spine SRS",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 274,
      "start_date": "2023-12-18",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-07-16",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06173401"
    },
    {
      "nct_id": "NCT04220489",
      "title": "Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Opioid Dependence",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Placebo Comparator",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jacques E. Chelly",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 1,
      "start_date": "2019-12-17",
      "completion_date": "2022-11-19",
      "has_results": true,
      "last_update_posted_date": "2024-01-30",
      "last_synced_at": "2026-06-26T10:03:17.232Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04220489"
    }
  ]
}