{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Lymphangiomatosis",
    "query": {
      "condition": "Lymphangiomatosis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:45:41.447Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00975819",
      "title": "Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Kaposiform Hemangioendotheliomas",
        "Tufted Angioma",
        "Capillary Venous Lymphatic Malformation",
        "Venous Lymphatic Malformation",
        "Microcystic Lymphatic Malformation",
        "Mucocutaneous Lymphangiomatosis and Thrombocytopenia",
        "Capillary Lymphatic Arterial Venous Malformations",
        "PTEN Overgrowth Syndrome With Vascular Anomaly",
        "Lymphangiectasia Syndromes"
      ],
      "interventions": [
        {
          "name": "sirolimus",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Denise Martin Adams",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "31 Years",
        "sex": "ALL",
        "summary": "Up to 31 Years"
      },
      "enrollment_count": 61,
      "start_date": "2009-10",
      "completion_date": "2020-10",
      "has_results": true,
      "last_update_posted_date": "2026-01-06",
      "last_synced_at": "2026-05-22T06:45:41.447Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00975819"
    },
    {
      "nct_id": "NCT02156115",
      "title": "Characterization of the Pathogenesis of Primary and Secondary Lymphatic Disorders",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphangiomatosis",
        "Lymphedema",
        "Lymphangiectasia",
        "Pulmonary Lymphangiectasia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "2 Years to 90 Years"
      },
      "enrollment_count": 14,
      "start_date": "2015-03-23",
      "completion_date": "2024-04-01",
      "has_results": false,
      "last_update_posted_date": "2024-04-11",
      "last_synced_at": "2026-05-22T06:45:41.447Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02156115"
    },
    {
      "nct_id": "NCT02744027",
      "title": "Imaging of Lymphatic Anomalies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gorham Disease",
        "Lymphatic Diseases",
        "Lymphangiomatosis"
      ],
      "interventions": [
        {
          "name": "Dynamic Contrast Enhanced Magnetic Resonance Lymphangiography (DCMRL)",
          "type": "OTHER"
        },
        {
          "name": "Heavy Weighted T2 Imaging (T2W)",
          "type": "OTHER"
        },
        {
          "name": "Lymph Node Access",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "2 Years to 80 Years"
      },
      "enrollment_count": 10,
      "start_date": "2016-04",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-03-21",
      "last_synced_at": "2026-05-22T06:45:41.447Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02744027"
    },
    {
      "nct_id": "NCT03001180",
      "title": "Identification of Biomarkers for Patients with Vascular Anomalies",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Vascular Anomaly",
        "Generalized Lymphatic Anomaly",
        "Kaposiform Hemangioendothelioma",
        "Kaposiform Lymphangiomatosis",
        "Gorham-Stout Disease",
        "Klippel Trenaunay Syndrome",
        "Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Day and older"
      },
      "enrollment_count": 1000,
      "start_date": "2015-04",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2024-11-06",
      "last_synced_at": "2026-05-22T06:45:41.447Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03001180"
    },
    {
      "nct_id": "NCT02399527",
      "title": "Lymphatic Anomalies Registry for the Assessment of Outcome Data",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphatic Malformation",
        "Generalized Lymphatic Anomaly (GLA)",
        "Central Conducting Lymphatic Anomaly",
        "CLOVES Syndrome",
        "Gorham-Stout Disease (\"Disappearing Bone Disease\")",
        "Blue Rubber Bleb Nevus Syndrome",
        "Kaposiform Lymphangiomatosis",
        "Kaposiform Hemangioendothelioma/Tufted Angioma",
        "Klippel-Trenaunay Syndrome",
        "Lymphangiomatosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2013-06",
      "completion_date": "2035-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-22T06:45:41.447Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02399527"
    },
    {
      "nct_id": "NCT01336790",
      "title": "International Lymphatic Disease and Lymphedema Registry",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphedema"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 5000,
      "start_date": "2009-03",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2023-11-22",
      "last_synced_at": "2026-05-22T06:45:41.447Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01336790"
    },
    {
      "nct_id": "NCT05731141",
      "title": "A Prospective Natural History Study of Lymphatic Anomalies",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphatic Diseases",
        "Lymphatic Abnormalities"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "1 Day to 100 Years"
      },
      "enrollment_count": 1200,
      "start_date": "2023-03-20",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-22T06:45:41.447Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05731141"
    }
  ]
}