{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Macular+Abnormalities", "query": { "condition": "Macular Abnormalities" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 92, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Macular+Abnormalities&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-22T05:56:00.636Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06203106", "title": "NYSCF Scientific Discovery Biobank", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "ALS", "Amyotrophic Lateral Sclerosis", "Alzheimer Disease", "Alzheimer Disease, Early Onset", "Alzheimer Disease, Late Onset", "Batten Disease", "Corticobasal Degeneration", "Dementia", "Frontotemporal Dementia", "Huntington Disease", "Lewy Body Disease", "Multiple Sclerosis", "Multiple System Atrophy", "Parkinson Disease", "Parkinson's Disease and Parkinsonism", "Progressive Supranuclear Palsy", "INAD", "Diabetes", "Diabetes Mellitus", "Diabetes Mellitus, Type 2", "Diabetes Mellitus, Type 1", "Macular Degeneration", "Ovarian Cancer", "Cervical Cancer", "Uterine Cancer", "Vaginal Cancer", "Vulvar Cancer", "PTSD", "Post Traumatic Stress Disorder" ], "interventions": [ { "name": "Biological Sample Collection", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "New York Stem Cell Foundation Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Days", "maximum_age": null, "sex": "ALL", "summary": "30 Days and older" }, "enrollment_count": 10000, "start_date": "2022-11-10", "completion_date": "2045-11-10", "has_results": false, "last_update_posted_date": "2025-03-03", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06203106" }, { "nct_id": "NCT05537220", "title": "Oral N-acetylcysteine for Retinitis Pigmentosa", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Retinitis Pigmentosa" ], "interventions": [ { "name": "N-acetylcysteine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 485, "start_date": "2023-10-11", "completion_date": "2030-05", "has_results": false, "last_update_posted_date": "2026-06-15", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 24, "location_summary": "Davis, California • Los Angeles, California • San Francisco, California + 21 more", "locations": [ { "city": "Davis", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05537220" }, { "nct_id": "NCT01676766", "title": "Novel Quantification Methods for Fluorescence to Detect Progression in Stargardt Disease", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Stargardt Disease" ], "interventions": [], "intervention_types": [], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "5 Years to 18 Years" }, "enrollment_count": 2, "start_date": "2012-09", "completion_date": "2016-10", "has_results": false, "last_update_posted_date": "2016-11-08", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01676766" }, { "nct_id": "NCT02140164", "title": "Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis Pigmentosa", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Retinitis Pigmentosa" ], "interventions": [ { "name": "Minocycline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Eye Institute (NEI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 7, "start_date": "2014-05", "completion_date": "2016-06", "has_results": true, "last_update_posted_date": "2024-04-17", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02140164" }, { "nct_id": "NCT05355415", "title": "Adaptive Optics Imaging of Outer Retinal Diseases", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Retinal Degeneration", "Age-Related Macular Degeneration", "Retinitis Pigmentosa", "Hydroxychloroquine Retinopathy", "Usher Syndromes", "Late-Onset Retinal Degeneration", "Cone Dystrophy", "Cone Rod Dystrophy", "Rod Cone Dystrophy", "Rod Dystrophy" ], "interventions": [ { "name": "Adaptive optics imaging", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Food and Drug Administration (FDA)", "sponsor_class": "FED", "healthy_volunteers": null, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 100, "start_date": "2021-08-27", "completion_date": "2028-09-30", "has_results": false, "last_update_posted_date": "2026-05-08", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 2, "location_summary": "Bethesda, Maryland • Silver Spring, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" }, { "city": "Silver Spring", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05355415" }, { "nct_id": "NCT01496625", "title": "National Eye Institute Biorepository for Retinal Diseases", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Age-Related Macular Degeneration", "Diabetic Retinopathy", "Von Hippel-Lindau Syndrome", "Retinal Disease", "Retinal Vein Occlusion" ], "interventions": [], "intervention_types": [], "sponsor": "National Eye Institute (NEI)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "2 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "2 Years to 120 Years" }, "enrollment_count": 650, "start_date": "2012-06-18", "completion_date": null, "has_results": false, "last_update_posted_date": "2026-06-30", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01496625" }, { "nct_id": "NCT07425574", "title": "A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Stargardt Disease", "Stargardt Macular Dystrophy", "Stargardt-like Macular Dystrophy" ], "interventions": [ { "name": "No Intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Astellas Pharma Global Development, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 90, "start_date": "2026-02-20", "completion_date": "2028-07-31", "has_results": false, "last_update_posted_date": "2026-07-17", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 12, "location_summary": "Phoenix, Arizona • Palo Alto, California • Sacramento, California + 9 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Palo Alto", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT07425574" }, { "nct_id": "NCT05481827", "title": "ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Age Related Macular Degeneration (AMD)" ], "interventions": [ { "name": "GT005", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Gyroscope Therapeutics Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": null, "sex": "ALL", "summary": "55 Years and older" }, "enrollment_count": 225, "start_date": "2022-07-12", "completion_date": "2028-06-02", "has_results": false, "last_update_posted_date": "2024-03-22", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 22, "location_summary": "Poway, California • Durango, Colorado • Gainesville, Florida + 18 more", "locations": [ { "city": "Poway", "state": "California" }, { "city": "Durango", "state": "Colorado" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Pompano Beach", "state": "Florida" }, { "city": "St. Petersburg", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05481827" }, { "nct_id": "NCT06805474", "title": "A Prospective Observational Study to Assess the Reliability and Validity of the MLSDT", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Macular Degeneration", "Geographic Atrophy", "Stargardt Disease" ], "interventions": [ { "name": "Observational", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Nanoscope Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2025-01-28", "completion_date": "2025-05-27", "has_results": false, "last_update_posted_date": "2025-03-24", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06805474" }, { "nct_id": "NCT00417846", "title": "Age-related Macular Degeneration: Detection of Onset of New Choroidal Neovascularization (AMD DOC Study)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Maculopathy, Age-Related", "Choroidal Neovascularization" ], "interventions": [], "intervention_types": [], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 98, "start_date": "2007-01", "completion_date": "2009-08", "has_results": false, "last_update_posted_date": "2009-10-05", "last_synced_at": "2026-07-22T05:56:00.636Z", "location_count": 4, "location_summary": "Beverly Hills, California • Baltimore, Maryland • Boston, Massachusetts + 1 more", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Beachwood", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00417846" } ] }