{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Major+Surgery",
    "query": {
      "condition": "Major Surgery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 314,
    "total_pages": 32,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Major+Surgery&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-25T19:07:08.328Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02741895",
      "title": "Using Fitbit to Monitor Ambulation in Patients After Surgery.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "General Surgery"
      ],
      "interventions": [
        {
          "name": "Fitbit monitoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 135,
      "start_date": "2016-05",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-01-30",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02741895"
    },
    {
      "nct_id": "NCT03555266",
      "title": "NSS-2 BRIDGE Device in Post-Operative Pain Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Pain",
        "Surgery",
        "Abdominal Cancer"
      ],
      "interventions": [
        {
          "name": "NSS-2 Bridge",
          "type": "DEVICE"
        },
        {
          "name": "Sham NSS-2 BRIDGE",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jacques E. Chelly",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2018-10-23",
      "completion_date": "2021-06-30",
      "has_results": true,
      "last_update_posted_date": "2021-11-01",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03555266"
    },
    {
      "nct_id": "NCT05104229",
      "title": "SAVES-IBD: Safety & Efficacy of Aspirin vs. Standard of Care for VTE Prophylaxis After IBD Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Crohn Disease",
        "Ulcerative Colitis",
        "Venous Thromboembolism"
      ],
      "interventions": [
        {
          "name": "Aspirin 81Mg Ec Tab",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stefan Holubar MD MS FACS, FASCRS",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 0,
      "start_date": "2024-06-01",
      "completion_date": "2026-01-01",
      "has_results": false,
      "last_update_posted_date": "2024-04-18",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05104229"
    },
    {
      "nct_id": "NCT04797156",
      "title": "Combined IV and Topical TXA in Major Spine Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Spine Surgery",
        "Back Pain"
      ],
      "interventions": [
        {
          "name": "High Dose Tranexamic acid",
          "type": "DRUG"
        },
        {
          "name": "Low Dose Tranexamic acid",
          "type": "DRUG"
        },
        {
          "name": "Tranexamic acid Topical",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 65,
      "start_date": "2021-03-03",
      "completion_date": "2024-08-15",
      "has_results": false,
      "last_update_posted_date": "2025-04-04",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04797156"
    },
    {
      "nct_id": "NCT03108482",
      "title": "Co-crystal E-58425 vs Tramadol and Celecoxib for Moderate to Severe Acute Pain After Bunionectomy. Phase III Clinical Trial.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Post-surgical Pain"
      ],
      "interventions": [
        {
          "name": "Co-crystal E-58425 (Tramadol/Celecoxib)",
          "type": "DRUG"
        },
        {
          "name": "Tramadol (Ultram®)",
          "type": "DRUG"
        },
        {
          "name": "Celecoxib (Celebrex®)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Esteve Pharmaceuticals, S.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 637,
      "start_date": "2017-03-14",
      "completion_date": "2017-11-28",
      "has_results": true,
      "last_update_posted_date": "2019-01-24",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 5,
      "location_summary": "Phoenix, Arizona • Anaheim, California • Pasadena, Maryland + 2 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Pasadena",
          "state": "Maryland"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03108482"
    },
    {
      "nct_id": "NCT01221961",
      "title": "Masimo Radical-7 Monitor a Useful Adjuvant During Major Spine Surgery",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Spine Surgery Procedure"
      ],
      "interventions": [
        {
          "name": "Masimo Radical-7",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 62,
      "start_date": "2010-10",
      "completion_date": "2013-04",
      "has_results": false,
      "last_update_posted_date": "2013-11-15",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01221961"
    },
    {
      "nct_id": "NCT04165694",
      "title": "Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bariatric Surgery Candidate",
        "Severe Obesity"
      ],
      "interventions": [
        {
          "name": "Single Anastomosis Duodenal Ileal Bypass (SADI)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 54,
      "start_date": "2019-10-15",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-14",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04165694"
    },
    {
      "nct_id": "NCT07194265",
      "title": "A Clinical Trial Assessing the Safety and Effectiveness of the DurAVR® THV System",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Aortic Stenosis",
        "Valve-in-valve Procedures"
      ],
      "interventions": [
        {
          "name": "TAVR with DurAVR® THV",
          "type": "DEVICE"
        },
        {
          "name": "TAVR with SAPIEN THV series or the Evolut THV series",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Anteris Technologies Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1650,
      "start_date": "2025-10-21",
      "completion_date": "2038-03",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 4,
      "location_summary": "San Francisco, California • The Bronx, New York • Cincinnati, Ohio + 1 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Germantown",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07194265"
    },
    {
      "nct_id": "NCT00003744",
      "title": "Gemcitabine in Treating Patients With Advanced Salivary Gland Cancer That Cannot Be Removed During Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "gemcitabine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dana-Farber Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "1998-11",
      "completion_date": "2004-05",
      "has_results": false,
      "last_update_posted_date": "2017-01-19",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 6,
      "location_summary": "Chicago, Illinois • Boston, Massachusetts • Burlington, Massachusetts + 1 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Burlington",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00003744"
    },
    {
      "nct_id": "NCT01490164",
      "title": "Transfusion Requirements During Spinal Surgery for Severe Scoliosis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Scoliosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "Up to 19 Years"
      },
      "enrollment_count": 50,
      "start_date": "2009-08",
      "completion_date": "2013-11",
      "has_results": false,
      "last_update_posted_date": "2013-11-13",
      "last_synced_at": "2026-06-25T19:07:08.328Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01490164"
    }
  ]
}