{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Male+Infertility%2C+Azoospermia",
    "query": {
      "condition": "Male Infertility, Azoospermia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Male+Infertility%2C+Azoospermia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-21T23:19:33.829Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07074015",
      "title": "IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surgical Specimens",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infertility",
        "Azoospermia"
      ],
      "interventions": [
        {
          "name": "Use of IntelliWell to identify and localize sperm for ICSI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 20,
      "start_date": "2026-04-15",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07074015"
    },
    {
      "nct_id": "NCT03323801",
      "title": "RA-4: 13-cis Retinoic Acid for Treatment of Men With Azoospermia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Male Infertility, Azoospermia"
      ],
      "interventions": [
        {
          "name": "13-cis retinoic acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "MALE",
        "summary": "21 Years to 60 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2017-07-25",
      "completion_date": "2019-05-31",
      "has_results": true,
      "last_update_posted_date": "2021-10-26",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03323801"
    },
    {
      "nct_id": "NCT05479474",
      "title": "Platelet Rich Plasma Testis Treatment for Infertile Men",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Male Infertility",
        "Nonobstructive Azoospermia",
        "Azoospermia"
      ],
      "interventions": [
        {
          "name": "Platelet rich plasma",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2023-01-18",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-13",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05479474"
    },
    {
      "nct_id": "NCT07481370",
      "title": "Isotretinoin vs hCG for Male Infertility Due to Low or Absent Sperm",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Oligospermia",
        "Azoospermia, Nonobstructive",
        "Infertility"
      ],
      "interventions": [
        {
          "name": "isotretinoin",
          "type": "DRUG"
        },
        {
          "name": "Human chorionic gonadotrophin (hCG)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "19 Years to 50 Years · Male only"
      },
      "enrollment_count": 100,
      "start_date": "2026-04-13",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07481370"
    },
    {
      "nct_id": "NCT03291522",
      "title": "Retrieval of Sperm From Men With Azoospermia Using Ultrasound-guided Rete Testis Aspiration",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Azoospermia, Nonobstructive",
        "Infertility, Male"
      ],
      "interventions": [
        {
          "name": "Ultrasound-guided rete testis flushing and aspiration",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 50,
      "start_date": "2019-05-10",
      "completion_date": "2027-09-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-10",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03291522"
    },
    {
      "nct_id": "NCT06566599",
      "title": "Preimplantation Genetic Testing for Aneuploidy (PGT-A) in Couples With Non-obstructive Azoospermia (NOA)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Non-obstructive Azoospermia",
        "Male Infertility"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Inception Fertility Research Institute, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 400,
      "start_date": "2024-08-19",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-04-16",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06566599"
    },
    {
      "nct_id": "NCT00044369",
      "title": "Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Varicocele",
        "Male Infertility",
        "Hypospermatogenesis",
        "Non-Obstructive Azoospermia"
      ],
      "interventions": [
        {
          "name": "Varicocele repair",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Institute of Environmental Health Sciences (NIEHS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "21 Years to 55 Years · Male only"
      },
      "enrollment_count": 400,
      "start_date": "2000-05",
      "completion_date": "2005-04",
      "has_results": false,
      "last_update_posted_date": "2006-09-04",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 2,
      "location_summary": "Camden, New Jersey • Manhasset, New York",
      "locations": [
        {
          "city": "Camden",
          "state": "New Jersey"
        },
        {
          "city": "Manhasset",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00044369"
    },
    {
      "nct_id": "NCT04053309",
      "title": "Round Spermatid Injection Protocol",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Male Infertility Due to Azoospermia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Reproductive Medicine Associates of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 3,
      "start_date": "2019-08-16",
      "completion_date": "2021-01-08",
      "has_results": false,
      "last_update_posted_date": "2021-05-19",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 1,
      "location_summary": "Basking Ridge, New Jersey",
      "locations": [
        {
          "city": "Basking Ridge",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04053309"
    },
    {
      "nct_id": "NCT07357701",
      "title": "Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Ovarian Insufficiency",
        "Azoospermia",
        "Oligospermia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 500,
      "start_date": "2026-03-11",
      "completion_date": "2031-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Rockville, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07357701"
    },
    {
      "nct_id": "NCT06990906",
      "title": "Evaluating the Safety and Clinical Efficacy of the BAIBYS™ System in Intracytoplasmic Sperm Injection (ICSI)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Male Infertility, Azoospermia"
      ],
      "interventions": [
        {
          "name": "BAIBYS Sperm selection",
          "type": "DEVICE"
        },
        {
          "name": "Intra cytoplasmatic sperm injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Conventional manual sperm selection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "BAIBYS Fertility",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "42 Years",
        "sex": "ALL",
        "summary": "21 Years to 42 Years"
      },
      "enrollment_count": 260,
      "start_date": "2026-03-15",
      "completion_date": "2026-10-15",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-05-21T23:19:33.829Z",
      "location_count": 1,
      "location_summary": "Stamford, Connecticut",
      "locations": [
        {
          "city": "Stamford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06990906"
    }
  ]
}