{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Malignant+Bile+Duct+Obstruction",
    "query": {
      "condition": "Malignant Bile Duct Obstruction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T21:01:21.029Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01590394",
      "title": "Patency of a Prototype Large Plastic Biliary Stent in the Palliation of Malignant Distal Biliary Strictures.",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stricture",
        "Obstruction",
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Large plastic biliary stent",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 3,
      "start_date": "2012-09",
      "completion_date": "2016-04",
      "has_results": true,
      "last_update_posted_date": "2017-10-17",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01590394"
    },
    {
      "nct_id": "NCT00003923",
      "title": "Photodynamic Therapy in Treating Patients With Cancer of the Bile Duct, Gallbladder, or Pancreas",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Extrahepatic Bile Duct Cancer",
        "Gallbladder Cancer",
        "Liver Cancer",
        "Pancreatic Cancer"
      ],
      "interventions": [
        {
          "name": "porfimer sodium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "1999-03",
      "completion_date": "2002-02",
      "has_results": false,
      "last_update_posted_date": "2013-03-04",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00003923"
    },
    {
      "nct_id": "NCT00433771",
      "title": "A Study of the WallFlex™ Biliary Fully-covered Stent for the Palliative Treatment of Malignant Bile Duct Obstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cholestasis, Extrahepatic"
      ],
      "interventions": [
        {
          "name": "WallFlex™ Biliary Fully Covered Metal Stent placement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2007-03",
      "completion_date": "2008-05",
      "has_results": true,
      "last_update_posted_date": "2010-06-29",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 10,
      "location_summary": "San Francisco, California • Aurora, Colorado • Minneapolis, Minnesota + 7 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00433771"
    },
    {
      "nct_id": "NCT06694038",
      "title": "Needle-Knife Fistulotomy Vs. Standard Cannulation Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Biliary Obstruction Due to Common Bile Duct Stone",
        "Malignant Bile Duct Obstruction"
      ],
      "interventions": [
        {
          "name": "Needle Knife Fistulotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "standard biliary cannulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 186,
      "start_date": "2019-01-31",
      "completion_date": "2021-07-01",
      "has_results": false,
      "last_update_posted_date": "2024-11-19",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06694038"
    },
    {
      "nct_id": "NCT01905384",
      "title": "Covered vs Uncovered Metal Stents for Palliative Biliary Decompression in Inoperable Malignant Distal Bile Duct Obstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Distal Bile Duct Obstruction"
      ],
      "interventions": [
        {
          "name": "Covered Self-expanding metal biliary stents (C-SEMS)",
          "type": "DEVICE"
        },
        {
          "name": "Uncovered Self-expanding metal biliary stents (U-SEMS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 6,
      "start_date": "2017-11-08",
      "completion_date": "2020-12-01",
      "has_results": true,
      "last_update_posted_date": "2022-03-31",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 2,
      "location_summary": "New York, New York • Nashville, Tennessee",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01905384"
    },
    {
      "nct_id": "NCT03951324",
      "title": "Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Biliary Stricture",
        "Pancreas Cancer",
        "Cholangiocarcinoma",
        "Bile Duct Cancer",
        "Bile Duct Neoplasms Malignant",
        "Bile Duct Neoplasms",
        "Bile Duct Lesions",
        "Bile Duct Obstruction",
        "Bile Duct Diseases",
        "Bile Duct Obstruction, Extrahepatic",
        "Bile Duct Stenosi",
        "Bile Duct Adenoma",
        "Pancreatic Duct Stricture",
        "Pancreatic Duct Stenosis",
        "Pancreatic Duct Obstruction",
        "Pancreatic Ductal Adenocarcinoma",
        "Primary Sclerosing Cholangitis"
      ],
      "interventions": [
        {
          "name": "Interobserver agreement or Interrater agreement",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Innovative Digestive Health Education and Research Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2019-05-10",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-08-12",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03951324"
    },
    {
      "nct_id": "NCT00579865",
      "title": "Quality Of Life in Patients With Malignant Biliary Obstruction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gallbladder Cancer",
        "Liver Cancer",
        "Bile Duct Cancer"
      ],
      "interventions": [
        {
          "name": "questionnaires",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 124,
      "start_date": "2005-05",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2010-01-14",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00579865"
    },
    {
      "nct_id": "NCT01543607",
      "title": "Endoscopic Therapy of Malignant Bile Duct Strictures",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstruction of Biliary Tree",
        "Biliary Tract Cancer",
        "Biliary Tract Neoplasms"
      ],
      "interventions": [
        {
          "name": "Radiofrequency ablation catheter (Habib EndoHBP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2012-02",
      "completion_date": "2014-02",
      "has_results": true,
      "last_update_posted_date": "2017-04-24",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01543607"
    },
    {
      "nct_id": "NCT05826639",
      "title": "A Study of Endobiliary Radiofrequency Ablation in Malignant Biliary Obstructions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Biliary Stricture"
      ],
      "interventions": [
        {
          "name": "Temperature-sensitive radiofrequency ablation",
          "type": "PROCEDURE"
        },
        {
          "name": "No intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 176,
      "start_date": "2023-04-13",
      "completion_date": "2024-11-18",
      "has_results": false,
      "last_update_posted_date": "2025-02-27",
      "last_synced_at": "2026-07-22T21:01:21.029Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05826639"
    }
  ]
}