{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Malignant+Neoplasm+of+Large+Intestine&page=48",
    "query": {
      "condition": "Malignant Neoplasm of Large Intestine",
      "page": 48
    },
    "page_size": 10
  },
  "pagination": {
    "page": 48,
    "page_size": 10,
    "total_count": 1214,
    "total_pages": 122,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Malignant+Neoplasm+of+Large+Intestine&page=49&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Malignant+Neoplasm+of+Large+Intestine&page=47&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T21:25:44.000Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01322724",
      "title": "Comparing Warm Versus Cool Temperature Water During Colonoscopy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colonoscopy"
      ],
      "interventions": [
        {
          "name": "Warm vs Cool water",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "OHSU Knight Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 175,
      "start_date": "2011-06",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2012-05-25",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01322724"
    },
    {
      "nct_id": "NCT02726360",
      "title": "Physician Use of Non-English Language Skills in Cancer Care",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer",
        "Colon Cancer",
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "survey",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Audio record",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 71,
      "start_date": "2015-12-14",
      "completion_date": "2023-08-21",
      "has_results": false,
      "last_update_posted_date": "2023-08-23",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 5,
      "location_summary": "Jamaica, New York • New York, New York • Queens, New York + 1 more",
      "locations": [
        {
          "city": "Jamaica",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Queens",
          "state": "New York"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02726360"
    },
    {
      "nct_id": "NCT01339000",
      "title": "Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Colon Cancer",
        "Bladder Cancer"
      ],
      "interventions": [
        {
          "name": "Glycosylated Recombinant Human Interleukin-7",
          "type": "DRUG"
        },
        {
          "name": "Diphtheria/Tetanus Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Polio Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pneumococcal Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Hepatitis A Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Hepatitis B Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "60 Years to 100 Years"
      },
      "enrollment_count": 1,
      "start_date": "2011-04",
      "completion_date": "2016-04",
      "has_results": true,
      "last_update_posted_date": "2016-06-22",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • New York, New York",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01339000"
    },
    {
      "nct_id": "NCT01787500",
      "title": "Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "BRAF NP_004324.2:p.V600X",
        "KRAS wt Allele",
        "Metastatic Malignant Solid Neoplasm",
        "Stage IV Colorectal Cancer AJCC v7",
        "Stage IVA Colorectal Cancer AJCC v7",
        "Stage IVB Colorectal Cancer AJCC v7",
        "Unresectable Solid Neoplasm"
      ],
      "interventions": [
        {
          "name": "Cetuximab",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Irinotecan Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Pharmacological Study",
          "type": "OTHER"
        },
        {
          "name": "Vemurafenib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2013-02-15",
      "completion_date": "2022-01-19",
      "has_results": false,
      "last_update_posted_date": "2026-04-23",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01787500"
    },
    {
      "nct_id": "NCT03700593",
      "title": "Feasibility and Safety of Single Port Robot in Colorectal Procedures",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Colon Cancer",
        "Colon Polyp",
        "Rectal Cancer",
        "Diverticulitis",
        "Prolapse, Rectal",
        "Rectal Polyp",
        "Inflammatory Bowel Diseases"
      ],
      "interventions": [
        {
          "name": "Single Port Robotic Colorectal Surgery",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Marks Colorectal Surgical Associates",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 200,
      "start_date": "2018-10-15",
      "completion_date": "2020-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-02-19",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 1,
      "location_summary": "Wynnewood, Pennsylvania",
      "locations": [
        {
          "city": "Wynnewood",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03700593"
    },
    {
      "nct_id": "NCT01802320",
      "title": "Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Colon Mucinous Adenocarcinoma",
        "Colon Signet Ring Cell Adenocarcinoma",
        "Rectal Mucinous Adenocarcinoma",
        "Rectal Signet Ring Cell Adenocarcinoma",
        "Recurrent Colon Carcinoma",
        "Recurrent Rectal Carcinoma",
        "Stage IIIA Colon Cancer",
        "Stage IIIA Rectal Cancer",
        "Stage IIIB Colon Cancer",
        "Stage IIIB Rectal Cancer",
        "Stage IIIC Colon Cancer",
        "Stage IIIC Rectal Cancer",
        "Stage IVA Colon Cancer",
        "Stage IVA Rectal Cancer",
        "Stage IVB Colon Cancer",
        "Stage IVB Rectal Cancer"
      ],
      "interventions": [
        {
          "name": "Akt Inhibitor MK2206",
          "type": "DRUG"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Pharmacological Study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2013-03",
      "completion_date": "2015-08-05",
      "has_results": true,
      "last_update_posted_date": "2019-09-20",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01802320"
    },
    {
      "nct_id": "NCT04907643",
      "title": "Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer Pain",
        "Visceral Pain",
        "Gastrointestinal Neoplasms",
        "Cancer of Gastrointestinal Tract",
        "Small Intestine Cancer",
        "Pancreas Cancer",
        "Liver Cancer",
        "Colon Cancer",
        "Biliary Tract Cancer",
        "Stomach Cancer",
        "Rectum Cancer",
        "Peritoneal Cancer",
        "Gastrointestinal Cancer Metastatic",
        "Gastrointestinal Cancers - Anus",
        "Gastrointestinal Cancers - Stomach",
        "Gastrointestinal Cancers - Colorectal",
        "Gastrointestinal Cancers - Small Intestine",
        "Small Intestine Cancer Stage III",
        "Small Intestine Cancer Stage IV",
        "Small Intestine Cancer, Recurrent",
        "Pancreas Cancer, Stage III",
        "Pancreas Cancer, Stage IV",
        "Pancreas Cancer, Metastatic",
        "Pancreas Cancer, Recurrent",
        "Liver Cancer Stage IIIa",
        "Liver Cancer Stage IIIb",
        "Liver Cancer Stage IIIc",
        "Liver Cancer Stage IV",
        "Colon Cancer Stage III",
        "Colon Cancer Stage IV",
        "Stomach Cancer Stage III",
        "Stomach Cancer Stage IV",
        "Stomach Cancer Recurrent",
        "Rectum Cancer, Recurrent",
        "Gastrointestinal Cancers - Liver",
        "Anal Cancer",
        "Anal Cancer Stage III",
        "Anal Cancer Stage IV",
        "Anal Cancer Recurrent",
        "Anal Cancer Metastatic",
        "Anal Cancer, Stage IIIA",
        "Anal Cancer, Stage IIIB",
        "Appendix Cancer",
        "Ampullary Cancer",
        "Bile Duct Cancer",
        "Bile Duct Cancer Stage III",
        "Bile Duct Cancer Stage IV",
        "Bile Duct Cancer Stage IVA",
        "Bile Duct Cancer Stage IVB",
        "Bile Duct Cancer Recurrent",
        "Carcinoid Tumor",
        "Carcinoid Tumor of Pancreas",
        "Carcinoid Tumor of Large Intestine",
        "Carcinoid Tumor of GI System",
        "Carcinoid Tumor of Colon",
        "Carcinoid Tumor of Liver",
        "Carcinoid Tumor of Cecum",
        "Carcinoid Tumor of Ileum",
        "Carcinoid Tumor of Rectum",
        "Carcinoid Tumor of the Small Bowel",
        "Carcinoid Tumor of the Stomach",
        "Large Intestine Cancer",
        "Esophagus Cancer",
        "Esophagus Cancer, Stage III",
        "Esophagus Cancer, Stage IV",
        "Esophagus Cancer, Recurrent",
        "Gallbladder Cancer",
        "Gallbladder Cancer Stage III",
        "Gallbladder Cancer Stage IV",
        "Gastric (Stomach) Cancer",
        "Neuroendocrine Tumor",
        "Peritoneum Cancer",
        "Rectal Cancer",
        "Esophagus Cancer, Stage I",
        "Esophagus Cancer, Stage II",
        "Gallbladder Cancer Stage I",
        "Gallbladder Cancer Stage II",
        "Bile Duct Cancer Stage I",
        "Bile Duct Cancer Stage II"
      ],
      "interventions": [
        {
          "name": "PICO G2 4k",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 360,
      "start_date": "2021-10-05",
      "completion_date": "2027-03-16",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04907643"
    },
    {
      "nct_id": "NCT02665299",
      "title": "Plasma ctDNA in Patients Undergoing Diagnostic Colonoscopy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Colon Cancer",
        "Colon Adenomas",
        "Colon Polyps"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Pathway Genomics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 206,
      "start_date": "2016-01",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2017-08-21",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02665299"
    },
    {
      "nct_id": "NCT01211132",
      "title": "Cap Assisted Colonoscopy for the Detection of Colon Polyps",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adenoma",
        "Colon Polyps",
        "Colon Cancer"
      ],
      "interventions": [
        {
          "name": "Cap - Transparent retractable extension device.",
          "type": "DEVICE"
        },
        {
          "name": "Standard",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "American Society for Gastrointestinal Endoscopy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 462,
      "start_date": "2009-09",
      "completion_date": "2010-11",
      "has_results": false,
      "last_update_posted_date": "2010-09-29",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01211132"
    },
    {
      "nct_id": "NCT01116687",
      "title": "RO4929097 in Treating Patients With Metastatic Colorectal Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Recurrent Colon Cancer",
        "Recurrent Rectal Cancer",
        "Stage IV Colon Cancer",
        "Stage IV Rectal Cancer"
      ],
      "interventions": [
        {
          "name": "gamma-secretase/Notch signalling pathway inhibitor RO4929097",
          "type": "DRUG"
        },
        {
          "name": "laboratory biomarker analysis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2010-05",
      "completion_date": "2012-03",
      "has_results": true,
      "last_update_posted_date": "2014-05-20",
      "last_synced_at": "2026-10-23T21:25:44.000Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01116687"
    }
  ]
}