{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Manic+State", "query": { "condition": "Manic State" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 92, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Manic+State&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-08T04:38:28.800Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03257865", "title": "A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes, Associated With Bipolar I Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar I Disorder", "Manic Episode" ], "interventions": [ { "name": "Brexpiprazole", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 333, "start_date": "2017-09-19", "completion_date": "2019-01-22", "has_results": true, "last_update_posted_date": "2020-02-11", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 27, "location_summary": "Little Rock, Arkansas • Bellflower, California • Cerritos, California + 21 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Bellflower", "state": "California" }, { "city": "Cerritos", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03257865" }, { "nct_id": "NCT00982020", "title": "Study in Adolescents With Schizophrenia or Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar I Disorder", "Schizophrenia" ], "interventions": [ { "name": "Olanzapine", "type": "DRUG" }, { "name": "Standard behavioral weight intervention", "type": "BEHAVIORAL" }, { "name": "Intense behavioral weight intervention", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "13 Years to 17 Years" }, "enrollment_count": 203, "start_date": "2009-09", "completion_date": "2013-05", "has_results": true, "last_update_posted_date": "2014-12-17", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 4, "location_summary": "Lauderhill, Florida • Bloomfield Hills, Michigan • St Louis, Missouri + 1 more", "locations": [ { "city": "Lauderhill", "state": "Florida" }, { "city": "Bloomfield Hills", "state": "Michigan" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Bellevue", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00982020" }, { "nct_id": "NCT00825539", "title": "Pharmacodynamic/Pharmacokinetic Study of AQW051 in Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Schizophrenia" ], "interventions": [ { "name": "AQW051", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 68, "start_date": "2009-01", "completion_date": "2011-11", "has_results": false, "last_update_posted_date": "2020-12-24", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 7, "location_summary": "Los Angeles, California • Chicago, Illinois • Baltimore, Maryland + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00825539" }, { "nct_id": "NCT01396291", "title": "Efficacy and Safety of Asenapine in the Prevention of Recurrence of Mood Episodes in Participants With Bipolar 1 Disorder (P06384)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar 1 Disorder" ], "interventions": [ { "name": "asenapine", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 561, "start_date": "2011-12", "completion_date": "2015-06", "has_results": false, "last_update_posted_date": "2015-12-04", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 30, "location_summary": "Anaheim, California • Chino, California • Escondido, California + 25 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Chino", "state": "California" }, { "city": "Escondido", "state": "California" }, { "city": "National City", "state": "California" }, { "city": "Oakland", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01396291" }, { "nct_id": "NCT04058249", "title": "Accelerated Theta Burst Stimulation for Inpatients With Bipolar Disorder", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder, Manic", "Bipolar Disorder I" ], "interventions": [ { "name": "Accelerated intermittent theta-burst stimulation over right DLPFC", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 1, "start_date": "2019-11-01", "completion_date": "2021-12-20", "has_results": true, "last_update_posted_date": "2023-07-17", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 1, "location_summary": "Palo Alto, California", "locations": [ { "city": "Palo Alto", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04058249" }, { "nct_id": "NCT00012558", "title": "Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "lithium", "type": "DRUG" }, { "name": "valproate", "type": "DRUG" }, { "name": "bupropion", "type": "DRUG" }, { "name": "paroxetine", "type": "DRUG" }, { "name": "lamotrigine", "type": "DRUG" }, { "name": "risperidone", "type": "DRUG" }, { "name": "inositol", "type": "DRUG" }, { "name": "tranylcypromine", "type": "DRUG" }, { "name": "Cognitive Behavioral Therapy", "type": "BEHAVIORAL" }, { "name": "Family-focused Therapy", "type": "BEHAVIORAL" }, { "name": "Interpersonal and Social Rhythms Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": null, "sex": "ALL", "summary": "15 Years and older" }, "enrollment_count": 5000, "start_date": "1998-09", "completion_date": "2005-09", "has_results": false, "last_update_posted_date": "2007-05-04", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 11, "location_summary": "Stanford, California • Denver, Colorado • Boston, Massachusetts + 8 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Worcester", "state": "Massachusetts" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00012558" }, { "nct_id": "NCT00327756", "title": "Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bipolar Affective Disorder", "Depression" ], "interventions": [ { "name": "Coenzyme Q10", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2006-05", "completion_date": null, "has_results": false, "last_update_posted_date": "2011-11-23", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00327756" }, { "nct_id": "NCT01463111", "title": "Decision-Making in Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Lithium", "type": "DRUG" }, { "name": "Valproate", "type": "DRUG" }, { "name": "Lamotrigine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 37, "start_date": "2011-05", "completion_date": "2016-04", "has_results": true, "last_update_posted_date": "2017-05-31", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01463111" }, { "nct_id": "NCT00007761", "title": "Does Bipolar Disease Program (BDP) Intervention Improve Long Term Manic and Depressive Symptoms.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Bipolar Disorder Program", "type": "BEHAVIORAL" }, { "name": "Usual (psychiatric) Care", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "US Department of Veterans Affairs", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 382, "start_date": "1997-07", "completion_date": null, "has_results": false, "last_update_posted_date": "2009-09-24", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 13, "location_summary": "Tucson, Arizona • Palo Alto, California • San Diego, California + 10 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "West Los Angeles", "state": "California" }, { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT00007761" }, { "nct_id": "NCT00257166", "title": "Safety and Efficacy of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Ziprasidone oral capsules", "type": "DRUG" }, { "name": "placebo oral capsules", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer's Upjohn has merged with Mylan to form Viatris Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 238, "start_date": "2006-01", "completion_date": "2007-07", "has_results": true, "last_update_posted_date": "2021-03-03", "last_synced_at": "2026-06-08T04:38:28.800Z", "location_count": 50, "location_summary": "Scottsdale, Arizona • Orange, California • San Diego, California + 41 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Orange", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Altamonte Springs", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00257166" } ] }