{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Manipulation%2C+Spinal",
    "query": {
      "condition": "Manipulation, Spinal"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 89,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Manipulation%2C+Spinal&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T21:13:32.583Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06965920",
      "title": "Influence of Flexion Distraction Manipulation on Measures of Performance and Postural Control",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spine Condition",
        "Low Back Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Keiser University College of Chiropractic Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-05-15",
      "completion_date": "2026-05-14",
      "has_results": false,
      "last_update_posted_date": "2025-05-18",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 1,
      "location_summary": "West Palm Beach, Florida",
      "locations": [
        {
          "city": "West Palm Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06965920"
    },
    {
      "nct_id": "NCT03669354",
      "title": "Spinal Manipulation Services vs. Prescription Drug Therapy for Long-term Care",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Southern California University of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "64 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "64 Years to 84 Years"
      },
      "enrollment_count": 195,
      "start_date": "2019-05-01",
      "completion_date": "2020-06-30",
      "has_results": true,
      "last_update_posted_date": "2021-09-23",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 1,
      "location_summary": "Whittier, California",
      "locations": [
        {
          "city": "Whittier",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03669354"
    },
    {
      "nct_id": "NCT00769626",
      "title": "Standardizing Management of Patients With Low Back Pain in Primary Care and Physical Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Back Pain",
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Usual Care",
          "type": "OTHER"
        },
        {
          "name": "Early Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Intermountain Health Care, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 15,
      "start_date": "2008-09",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2011-07-18",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 3,
      "location_summary": "South Jordan, Utah • Taylorsville, Utah • West Jordan, Utah",
      "locations": [
        {
          "city": "South Jordan",
          "state": "Utah"
        },
        {
          "city": "Taylorsville",
          "state": "Utah"
        },
        {
          "city": "West Jordan",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00769626"
    },
    {
      "nct_id": "NCT00315120",
      "title": "Osteopathic Health Outcomes in Chronic Low Back Pain (OSTEOPATHIC) Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "A. Active OMT and active UST",
          "type": "PROCEDURE"
        },
        {
          "name": "B. Sham OMT and active UST",
          "type": "PROCEDURE"
        },
        {
          "name": "C. Active OMT and sham UST",
          "type": "PROCEDURE"
        },
        {
          "name": "D. Sham OMT and sham UST",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of North Texas Health Science Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "21 Years to 69 Years"
      },
      "enrollment_count": 455,
      "start_date": "2006-08",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2016-07-06",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00315120"
    },
    {
      "nct_id": "NCT02842918",
      "title": "The Effect of Thoracic Spine Manipulation on Peripheral Neurodynamic Mobility",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Musculoskeletal Manipulations"
      ],
      "interventions": [
        {
          "name": "Spinal Manual Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Spinal Range of Motion",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Shenandoah University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 43,
      "start_date": "2016-02",
      "completion_date": "2017-02",
      "has_results": false,
      "last_update_posted_date": "2017-04-25",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 1,
      "location_summary": "Winchester, Virginia",
      "locations": [
        {
          "city": "Winchester",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02842918"
    },
    {
      "nct_id": "NCT03581123",
      "title": "Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Pain",
        "Low Back Pain, Mechanical"
      ],
      "interventions": [
        {
          "name": "Supported-Self Management (SSM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Spinal Manipulation Therapy (SMT)",
          "type": "OTHER"
        },
        {
          "name": "SMT + SSM",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Standard Medical Care (SMC)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER",
        "COMBINATION_PRODUCT",
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2018-11-01",
      "completion_date": "2024-06-12",
      "has_results": true,
      "last_update_posted_date": "2025-10-16",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 3,
      "location_summary": "Minneapolis, Minnesota • Pittsburgh, Pennsylvania • Seattle, Washington",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03581123"
    },
    {
      "nct_id": "NCT00163124",
      "title": "A Randomized Controlled Trial of Best Approach to Care Compared to Diversified Chiropractic Adjustive Technique",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Headache",
        "Shoulder Pain"
      ],
      "interventions": [
        {
          "name": "spinal manipulation & patient education/nutrition",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Parker College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 155,
      "start_date": "2005-03",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2005-09-13",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00163124"
    },
    {
      "nct_id": "NCT00732394",
      "title": "A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "MSDR",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "MedAppraise, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 200,
      "start_date": "2008-08",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2008-08-12",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 1,
      "location_summary": "Clearwater, Florida",
      "locations": [
        {
          "city": "Clearwater",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00732394"
    },
    {
      "nct_id": "NCT01620905",
      "title": "Development of a Clinical Prediction Rulefor Neck Manipulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mechanical Neck Pain"
      ],
      "interventions": [
        {
          "name": "Manipulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Nevada, Las Vegas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 82,
      "start_date": "2008-11",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2016-05-12",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01620905"
    },
    {
      "nct_id": "NCT05884437",
      "title": "The Effects of Chiropractic in Adults With Metabolic Syndrome",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome"
      ],
      "interventions": [
        {
          "name": "Chiropractic adjustment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Life University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2025-01-01",
      "completion_date": "2025-12-16",
      "has_results": false,
      "last_update_posted_date": "2024-08-27",
      "last_synced_at": "2026-07-22T21:13:32.583Z",
      "location_count": 1,
      "location_summary": "Marietta, Georgia",
      "locations": [
        {
          "city": "Marietta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05884437"
    }
  ]
}