{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=McCune-Albright+Syndrome", "query": { "condition": "McCune-Albright Syndrome" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 15, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=McCune-Albright+Syndrome&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-22T07:27:31.086Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03231644", "title": "Fibrous Dysplasia, McCune-Albright Syndrome Patient Registry", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Fibrous Dysplasia", "McCune Albright Syndrome", "Mazabraud Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Tovah Burstein", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 600, "start_date": "2016-10-31", "completion_date": "2028-10", "has_results": false, "last_update_posted_date": "2025-08-12", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03231644" }, { "nct_id": "NCT05509595", "title": "Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Fibrous Dysplasia Of Bone" ], "interventions": [ { "name": "Burosumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "99 Years", "sex": "ALL", "summary": "1 Year to 99 Years" }, "enrollment_count": 12, "start_date": "2022-12-07", "completion_date": "2024-11-18", "has_results": true, "last_update_posted_date": "2026-02-02", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05509595" }, { "nct_id": "NCT00001181", "title": "Testolactone for the Treatment of Girls With LHRH Resistant Precocious Puberty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Polyostotic Fibrous Dysplasia", "Precocious Puberty" ], "interventions": [ { "name": "Testolactone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": 100, "start_date": "1982-10", "completion_date": "2003-05", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001181" }, { "nct_id": "NCT00278915", "title": "Faslodex in McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Puberty, Precocious", "McCune-Albright Syndrome" ], "interventions": [ { "name": "Fulvestrant", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "10 Years", "sex": "FEMALE", "summary": "1 Year to 10 Years · Female only" }, "enrollment_count": 30, "start_date": "2006-01-31", "completion_date": "2023-07-20", "has_results": true, "last_update_posted_date": "2024-03-05", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 7, "location_summary": "Birmingham, Alabama • Miami, Florida • Lexington, Kentucky + 4 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Miami", "state": "Florida" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "Baton Rouge", "state": "Louisiana" }, { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00278915" }, { "nct_id": "NCT00318097", "title": "Histamine Responsiveness in McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "McCune-Albright Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Mercy Hospital Kansas City", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": "39 Years", "sex": "ALL", "summary": "Up to 39 Years" }, "enrollment_count": 22, "start_date": "2004-08-01", "completion_date": "2007-08-01", "has_results": false, "last_update_posted_date": "2018-02-06", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Kansas City, Missouri", "locations": [ { "city": "Kansas City", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00318097" }, { "nct_id": "NCT02743377", "title": "PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Nervous System Disease" ], "interventions": [ { "name": "Brain PET Imaging with 11C Rolipram", "type": "OTHER" }, { "name": "Whole Body PET Baseline with 11C Rolipram", "type": "DRUG" }, { "name": "Whole Body PET Blocked with Roflumilast", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 16, "start_date": "2018-04-04", "completion_date": "2020-05-19", "has_results": true, "last_update_posted_date": "2020-10-19", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02743377" }, { "nct_id": "NCT04125862", "title": "Pain in Fibrous Dysplasia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Fibrous Dysplasia/McCune-Albright Syndrome" ], "interventions": [ { "name": "MRI-based Neuroimaging", "type": "DIAGNOSTIC_TEST" }, { "name": "Non-contrast MRI", "type": "DIAGNOSTIC_TEST" }, { "name": "18F-FDG-PET/CT", "type": "DIAGNOSTIC_TEST" }, { "name": "18F-NaF-PET/CT", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Boston Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "10 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "10 Years to 45 Years" }, "enrollment_count": 37, "start_date": "2021-01-05", "completion_date": "2025-12-01", "has_results": false, "last_update_posted_date": "2025-12-11", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04125862" }, { "nct_id": "NCT00017927", "title": "A Study of the Effects of Pegvisomant on Growth Hormone Excess in McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "McCune Albright Syndrome", "Polyostotic Fibrous Dysplasia" ], "interventions": [ { "name": "Pegvisomant", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 10, "start_date": "2001-06", "completion_date": "2005-06", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00017927" }, { "nct_id": "NCT00001973", "title": "Studies on Abnormal Bone From Patients With Polyostotic Fibrous Dysplasia and McCune Albright Syndrome", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Polyostotic Fibrous Dysplasia" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": null, "start_date": "1996-12-18", "completion_date": "2008-12-12", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001973" }, { "nct_id": "NCT00001851", "title": "Bone Marrow Injection to Replace Diseased Bone in Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Polyostotic Fibrous Dysplasia" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": null, "sex": "ALL", "summary": "4 Years and older" }, "enrollment_count": 50, "start_date": "1998-12-15", "completion_date": "2002-04-30", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-07-22T07:27:31.086Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001851" } ] }