{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mechanical+Ventilation+Weaning",
    "query": {
      "condition": "Mechanical Ventilation Weaning"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 32,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Mechanical+Ventilation+Weaning&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:15:54.198Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00366197",
      "title": "Prediction of Weaning Outcomes by Using Rate of Change of Rapid Shallow Breathing Index",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rapid Shallow Breathing"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Atlantic Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2005-01",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2014-01-16",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 1,
      "location_summary": "Morristown, New Jersey",
      "locations": [
        {
          "city": "Morristown",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00366197"
    },
    {
      "nct_id": "NCT02989246",
      "title": "Effort of Breathing Guided Ventilator Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventilators, Mechanical",
        "Work of Breathing"
      ],
      "interventions": [
        {
          "name": "Ventilator protocol",
          "type": "OTHER"
        },
        {
          "name": "Esophageal Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "37 Weeks",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "37 Weeks to 18 Years"
      },
      "enrollment_count": 32,
      "start_date": "2015-02-01",
      "completion_date": "2018-12-01",
      "has_results": true,
      "last_update_posted_date": "2024-10-30",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02989246"
    },
    {
      "nct_id": "NCT02656199",
      "title": "Change In Diaphragmatic Thickness Predicts Extubation Success",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mechanical Ventilation Complication"
      ],
      "interventions": [
        {
          "name": "Diaphragm Ultrasound",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Albert Einstein Healthcare Network",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 57,
      "start_date": "2015-01",
      "completion_date": "2017-01-13",
      "has_results": true,
      "last_update_posted_date": "2020-03-09",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02656199"
    },
    {
      "nct_id": "NCT01817608",
      "title": "Weaning From Mechanical Ventilation in the ICU",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Quality of Life"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Amal Jubran",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2004-09",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2013-03-25",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 1,
      "location_summary": "Maywood, Illinois",
      "locations": [
        {
          "city": "Maywood",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01817608"
    },
    {
      "nct_id": "NCT01140750",
      "title": "Variability Analysis as a Predictor of Liberation From Mechanical Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mechanical Ventilation",
        "Autonomic Nervous System Diseases"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2007-08",
      "completion_date": "2008-03",
      "has_results": false,
      "last_update_posted_date": "2010-06-09",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01140750"
    },
    {
      "nct_id": "NCT02399267",
      "title": "Frequency of Screening and SBT Technique Trial",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critically Ill"
      ],
      "interventions": [
        {
          "name": "Once daily screening",
          "type": "PROCEDURE"
        },
        {
          "name": "Twice daily screening",
          "type": "PROCEDURE"
        },
        {
          "name": "PS SBTs",
          "type": "PROCEDURE"
        },
        {
          "name": "T-piece SBTs",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Unity Health Toronto",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2016-07",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2019-04-04",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 2,
      "location_summary": "Long Beach, California • Atlanta, Georgia",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02399267"
    },
    {
      "nct_id": "NCT01751724",
      "title": "Caffeine to Reduce Mechanical Ventilation in Preterm Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Apnea",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Caffeine citrate",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "5 Days",
        "sex": "ALL",
        "summary": "1 Day to 5 Days"
      },
      "enrollment_count": 87,
      "start_date": "2012-12",
      "completion_date": "2016-01",
      "has_results": true,
      "last_update_posted_date": "2017-06-19",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01751724"
    },
    {
      "nct_id": "NCT01541462",
      "title": "Weaning From Prolonged Mechanical Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Mechanical Ventilatory Failure"
      ],
      "interventions": [
        {
          "name": "Weaning",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RML Specialty Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2000-10",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2012-03-01",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 1,
      "location_summary": "Hinsdale, Illinois",
      "locations": [
        {
          "city": "Hinsdale",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01541462"
    },
    {
      "nct_id": "NCT00813839",
      "title": "Automated Ventilator Controlled Weaning vs Daily Spontaneous Breathing Trial in Difficult to Wean ICU Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Mechanical Ventilation",
        "Weaning"
      ],
      "interventions": [
        {
          "name": "daily weaning trails",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2008-11",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2015-05-08",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00813839"
    },
    {
      "nct_id": "NCT02969226",
      "title": "The Frequency of Screening and SBT Technique Trial: The FAST Trial",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critically Ill"
      ],
      "interventions": [
        {
          "name": "Once daily screening",
          "type": "PROCEDURE"
        },
        {
          "name": "Twice daily screening",
          "type": "PROCEDURE"
        },
        {
          "name": "PS SBTs",
          "type": "PROCEDURE"
        },
        {
          "name": "T-piece SBTs",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Unity Health Toronto",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 760,
      "start_date": "2018-01-18",
      "completion_date": "2021-03",
      "has_results": false,
      "last_update_posted_date": "2018-12-05",
      "last_synced_at": "2026-06-11T04:15:54.198Z",
      "location_count": 5,
      "location_summary": "Long Beach, California • Los Angeles, California • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02969226"
    }
  ]
}