{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Medically+Unexplained+Symptoms",
    "query": {
      "condition": "Medically Unexplained Symptoms"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Medically+Unexplained+Symptoms&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T08:39:08.974Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00997451",
      "title": "Fatigue Self-Management in Primary Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Medically Unexplained Chronic Fatigue",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Cognitive-behavioral self-management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Symptom monitoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 107,
      "start_date": "2009-02",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2012-10-01",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00997451"
    },
    {
      "nct_id": "NCT04277715",
      "title": "Parent Training for Youth With Chronic Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Medically Unexplained Symptoms"
      ],
      "interventions": [
        {
          "name": "Parent training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "10 Years to 17 Years"
      },
      "enrollment_count": 16,
      "start_date": "2021-04-05",
      "completion_date": "2023-01-31",
      "has_results": false,
      "last_update_posted_date": "2023-09-14",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04277715"
    },
    {
      "nct_id": "NCT06423638",
      "title": "Feasibility of Virtual Tai Chi Easy for Registered Nurses",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transition Shock",
        "Nurses' Intention to Quit",
        "Stress",
        "Somatic Symptoms",
        "Burnout",
        "Trauma and Stressor Related Disorders"
      ],
      "interventions": [
        {
          "name": "Virtual Tai Chi Easy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-12-22",
      "completion_date": "2024-07-15",
      "has_results": false,
      "last_update_posted_date": "2024-05-21",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06423638"
    },
    {
      "nct_id": "NCT05120648",
      "title": "Effects of Biofeedback on Somatic Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Somatic Symptom"
      ],
      "interventions": [
        {
          "name": "Biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "15 Years to 60 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-09-01",
      "completion_date": "2024-09-01",
      "has_results": false,
      "last_update_posted_date": "2024-10-03",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05120648"
    },
    {
      "nct_id": "NCT03789084",
      "title": "Hybrid Trial of Brief Cognitive-Behavioral Therapy for Health Anxiety in Primary Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Illness Anxiety Disorder",
        "Somatic Symptom Disorder",
        "Health Anxiety"
      ],
      "interventions": [
        {
          "name": "Brief Cognitive-Behavioral Therapy for Health Anxiety",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Referral to mental health provider",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 68,
      "start_date": "2019-03-26",
      "completion_date": "2025-10-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-03",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "Lebanon, New Hampshire",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03789084"
    },
    {
      "nct_id": "NCT00276887",
      "title": "Cognitive Behavior Therapy for Somatization Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Somatoform Disorders"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavior Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychiatric Consultation Letter",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Medicine and Dentistry of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 84,
      "start_date": "1999-09",
      "completion_date": "2004-04",
      "has_results": false,
      "last_update_posted_date": "2014-02-20",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "Piscataway, New Jersey",
      "locations": [
        {
          "city": "Piscataway",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00276887"
    },
    {
      "nct_id": "NCT00468013",
      "title": "A Computer-Based Intervention for Medically Unexplained Physical Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fibromyalgia",
        "Irritable Bowel Syndrome",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Resilience Building Exercises",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Journaling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Medicine and Dentistry of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2007-03",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2015-02-09",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00468013"
    },
    {
      "nct_id": "NCT05573919",
      "title": "VivAer: A Correlation Between Symptom Scores and Objective Findings",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nasal Obstruction",
        "Medically Unexplained Symptoms",
        "Airway Obstruction",
        "Airway Remodeling"
      ],
      "interventions": [
        {
          "name": "VivAer Stylus",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2022-10-07",
      "completion_date": "2024-10",
      "has_results": false,
      "last_update_posted_date": "2024-02-21",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Skokie, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Skokie",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05573919"
    },
    {
      "nct_id": "NCT04899687",
      "title": "Study of Dextromethorphan in OCD and Related Disorders",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Obsessive-Compulsive Disorder",
        "Illness Anxiety Disorder",
        "Body Dysmorphic Disorders",
        "Somatic Symptom Disorder"
      ],
      "interventions": [
        {
          "name": "Fluoxetine",
          "type": "DRUG"
        },
        {
          "name": "Dextromethorphan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2022-01-20",
      "completion_date": "2028-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04899687"
    },
    {
      "nct_id": "NCT03986125",
      "title": "Student Anxiety & Stress Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Somatic Symptom Disorder"
      ],
      "interventions": [
        {
          "name": "Emotional Awareness & Expression Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness Meditation Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 53,
      "start_date": "2019-07-05",
      "completion_date": "2020-04-28",
      "has_results": false,
      "last_update_posted_date": "2020-07-16",
      "last_synced_at": "2026-07-22T08:39:08.974Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03986125"
    }
  ]
}